Protein targeting to subnuclear higher order structures: A new level of regulation and coordination of nuclear processes

Journal of Cellular Biochemistry

Volumn 70, Issue 2, 1998, Pages 222-230

  Cardoso, M Cristina ^a   Leonhardt, Heinrich ^a,b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b FRANZ VOLHARD CLINIC   (Germany)

Author keywords

Cell cycle; DNA ligase I; DNA methyltransferase; DNA replication; Functional organization of the nucleus; Nuclear matrix; Nucleolus; RNA splicing; Speckled compartment; Targeting sequence

Indexed keywords

DNA METHYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

CELL CYCLE; CELL METABOLISM; CELL NUCLEUS MATRIX; DNA METHYLATION; DNA REPLICATION; ENZYME ACTIVITY; JELLYFISH; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN TARGETING; REVIEW; RNA SPLICING;

ANIMALS; BIOLOGICAL TRANSPORT; CELL NUCLEUS; HUMANS; NUCLEAR PROTEINS;

MAMMALIA;

EID: 0031804026     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19980801)70:2<222::AID-JCB8>3.0.CO;2-Q     Document Type: Review

References (33)

1. Berezney R, Coffey DS (1974): Identification of a nuclear protein matrix. Biochem Biophys Res Commun 60:1410-1417.
2. Berezney R, Coffey DS (1975): Nuclear protein matrix: Association with newly synthesized DNA. Science 189: 291-293.
3. Berezney R, Mortillaro MJ, Ma H, Wei X, Samarabandu J (1995): The nuclear matrix: A structural milieu for genomic function. Int Rev Cytol 162A:1-65.
4. Calza RE, Eckhardt LA, DelGiudice T, Schildkraut CL (1984): Changes in gene position are accompanied by a change in time of replication. Cell 36:689-696.
5. Capco DG, Wan KM, Penman S (1982): The nuclear matrix: Three-dimensional architecture and protein composition. Cell 29:847-858.
6. Cardoso MC, Joseph C, Rahn H-P, Reusch R, Nadal-Ginard B, Leonhardt H (1997): Mapping and utilization of a sequence that targets DNA ligase I to sites of DNA replication in vivo. J Cell Biol. 139:579-587.
7. Cardoso MC, Leonhardt H (1998): Differentiation, development and programmed cell death. In Stein G, Baserga R, Denhardt D, Giordano A (eds): "The Molecular Basis of Cell Cycle and Growth Control." New York: John Wiley & Sons (in press).
8. Cardoso MC, Leonhardt H, Nadal-Ginard B (1993): Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication. Cell 74:979-992.
9. Cook PR (1988): The nucleoskeleton: Artefact, passive framework or active site? J Cell Sci 90:1-6.
10. Fey EG, Krochmalnic G, Penman S (1986): The nonchromatin substructures of the nucleus: The ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy. J Cell Biol 102:1654-1665.
11. Granboulan N, Granboulan P (1965): Cytochimie ultrastructurale du nucleole. Exp Cell Res 38:604-619.
12. Hatanaka M (1990): Discovery of the nucleolar targeting signal. Bioessays 12:143-148.
13. Hatton KS, Dhar V, Brown EH, Iqbal MA, Stuart S, Didamo VT, Schildkraut CL (1988): Replication program of active and inactive multigene families in mammalian cells. Mol Cell Biol 8:2149-2158.
14. He DC, Nickerson JA, Penman S (1990): Core filaments of the nuclear matrix. J Cell Biol 110:569-580.
15. Hozak P, Cook PR (1994): Replication Factories. Trends in Cell Biology 4:48-52.
16. Jackson DA, Cook PR (1985): A general method for preparing chromatin containing intact DNA. Embo J 4:913-918.
17. Jackson DA, Cook PR (1988): Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat. Embo J 7:3667-3677.
18. Jackson DA, Cook PR (1995): The structural basis of nuclear function. Int Rev Cytol 162A:125-149.
19. Kalderon D, Roberts BL, Richardson WD, Smith AE (1984): A short amino acid sequence able to specify nuclear location. Cell 39:499-509.
20. Lamond AI, Carmo-Fonseca M (1993): The coiled body. Trends Cell Biol 3:198-204.
21. Leonhardt H, Bestor TH (1993): Structure, function and regulation of mammalian DNA methyltransferase. In Jost JP, Saluz HP (eds): "DNA Methylation: Molecular Biology and Biological Significance." Basel: Switzerland: Birkäuser Verlag, pp 109-119.
22. Leonhardt H, Cardoso MC (1995): Targeting and association of proteins with functional domains in the nucleus: The insoluble solution. Intl Rev Cytol 162B:303-335.
23. Leonhardt H, Page AW, Weier HU, Bestor TH (1992): A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71: 865-873.
24. Li E, Bestor TH, Jaenisch R (1992): Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
25. Li H, Bingham PM (1991): Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing. Cell 67:335-342.
26. Misteli T, Caceres JF, Spector DL (1997): The dynamics of a pre-mRNA splicing factor in living cells. Nature 387:523-527.
27. Nickerson JA, Blencowe BJ, Penman S (1995): The architectural organization of nuclear metabolism. Int Rev Cytol 162A:67-123.
28. Scheer U, Weisenberger D (1994): The nucleolus. Curr Opin Cell Biol 6:354-359.
29. Sobczak-Thepot J, Harper F, Florentin Y, Zindy F, Brechot C, Puvion E (1993): Localization of cyclin A at the sites of cellular DNA replication. Exp Cell Res 206:43-48.
30. Spector DL (1993): Macromolecular domains within the cell nucleus. Annu Rev Cell Biol 9:265-315.
31. Wu Z, Murphy C, Gall JG (1994): Human p80-coilin is targeted to sphere organelles in the amphibian germinal vesicle. Mol Biol Cell 5:1119-1127.
32. Xing Y, Johnson CV, Moen PT, Jr., McNeil JA, Lawrence J (1995): Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains. J Cell Biol 131:1635-1647.
33. Xing Y, Lawrence JB (1993): Nuclear RNA tracks: Structural basis for transcription and splicing? Trends Cell Biol 3:346-353.