Synthesis of novel unnatural amino acid as a building block and its incorporation into an antimicrobial peptide

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 12, 1999, Pages 2985-2990

  Oh, Jong Eun ^a   Lee, Keun Hyeung ^a  

^a Mogam Biotechnology Research Institute   (South Korea)

Author keywords

Amino acids and derivatives; Antimicrobial compounds; Depsipeptides; Solid phase synthesis

Indexed keywords

AMINO ACID; ANTIINFECTIVE AGENT; LYSINE; PEPTIDE; PROTEINASE;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG DESIGN; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HALF LIFE TIME; MINIMUM INHIBITORY CONCENTRATION; PEPTIDE SYNTHESIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SERUM; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; CIRCULAR DICHROISM; COMBINATORIAL CHEMISTRY TECHNIQUES; HALF-LIFE; MAGNETIC RESONANCE SPECTROSCOPY; MICE; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033370537     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00247-3     Document Type: Article

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