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Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 23, 2000, Pages 12493-12497

2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: Formation of a lung carcinogen precursor

(4) Hecht, Stephen S a Hochalter, Bradley J a Villalta, Peter W a Murphy, Sharon E a

a UNIVERSITY OF MINNESOTA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 4 HYDROXY 4 (3 PYRIDYL)BUTANOIC ACID; 4 OXO 4 (3 PYRIDYL)BUTANOIC ACID; AMINOKETONE; BUTYRIC ACID DERIVATIVE; CARCINOGEN; COTININE; CYTOCHROME P450 2A6; CYTOCHROME P450 ISOENZYME; HYDROXYACID; NICOTINE; OXOACID; UNCLASSIFIED DRUG;

CHEMICAL REACTION; CHEMICAL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG HYDROXYLATION; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; MASS SPECTROMETRY; PRIORITY JOURNAL; REACTION ANALYSIS;

MAMMALIA; NICOTIANA TABACUM;

EID: 0033749374 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.220207697 Document Type: Article

Times cited : (136)

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