Coordinate induction of collagenase-1, stromelysin-1 and urokinase plasminogen activator (uPA) by the 120-kDa cell-binding fibronectin fragment in fibrocartilaginous cells: uPA contributes to activation of procollagenase-1

Matrix Biology

Volumn 19, Issue 7, 2000, Pages 657-669

  Hu, Bo ^a   Kapila, Yvonne L ^a   Buddhikot, Madhavee ^a   Shiga, Momotoshi ^a   Kapila, Sunil ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fibrocartilaginous cells; Fibronectin; Matrix metalloproteinases; Plasminogen activator; Tissue inhibitors of metalloproteinases

Indexed keywords

ANTIBODY; ARGINYLGLYCYLASPARTIC ACID; COLLAGENASE; FIBRONECTIN; FIBRONECTIN FRAGMENT; INTEGRIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PLASMINOGEN ACTIVATOR; PROCOLLAGENASE; PROTEOGLYCAN; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; UROKINASE;

ANIMAL CELL; ARTHRITIS; ARTICLE; CARTILAGE CELL; CONCENTRATION RESPONSE; CONNECTIVE TISSUE CELL; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME INHIBITION; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST; JOINT DEGENERATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INDUCTION; RABBIT; SYNOVIAL FLUID; WESTERN BLOTTING;

ANIMALS; CARTILAGE; CELLS, CULTURED; COLLAGENASES; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PRECURSORS; FEMALE; FIBRONECTINS; MATRIX METALLOPROTEINASE 3; PEPTIDE FRAGMENTS; RABBITS; RECEPTORS, FIBRONECTIN; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; URINARY PLASMINOGEN ACTIVATOR;

EID: 0033732004     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(00)00114-1     Document Type: Article

References (47)

1. Extracellular matrix degradation
2. Urokinase-type plasminogen activator gene regulation by polyomavirus middle-T antigen
3. Matrix metalloproteinases: a review
4. Transcriptional control of matrix metalloproteinases and the tissue inhibitors of matrix metalloproteinases
5. The immunoreactivity, ligand and cell binding characteristics of rheumatoid synovial fluid fibronectin
6. Fibronectin, cartilage and osteoarthritis
7. Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates
8. Endothelial cell surface actin serves as a binding site for plasminogen, tissue plasminogen activator and lipoprotein(a)
9. The role of proteinases in cartilage destruction
10. Cloning of cDNA for rabbit proactivator; a metalloproteinase that activates synovial cell collagenase, that shares homology with stromelysin and transin, and that is coordinately regulated with collagenase
11. The catabolism of extracellular matrix components
12. Fragmented fibronectin and other synovial fluid proteins in chronic arthritis: their relation to immune complexes
13. Tissue cooperation in a proteolytic cascade activating human interstitial collagenase
14. Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture
15. Intrarticular injection of fibronectin fragments causes severe depletion of cartilage proteoglycans in vivo
16. Cooperative signaling by α5β1 and α4β1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin
17. Molecular biology of fibronectin
18. Integrins: a family of cell surface receptors
19. Characterization and identification of proteinases and proteinase inhibitors synthesized by temporomandibular joint disc cells
20. Fibronectin and fibronectin fragments modulate the expression of proteinases and proteinase inhibitors in human periodontal ligament cells
21. Biology of TMJ degeneration: the role of matrix-degrading enzymes
22. Targeted induction of collagenase and stromelysin by relaxin in unprimed and β-estradiol-primed diarthrodial joint fibrocartilaginous cells but not in synoviocytes
23. Mechanisms of matrix degradation in rheumatoid arthritis
24. Stimulation of urokinase expression by TNF-alpha requires the activation of binding sites for the AP-1 and PEA-3 transcription factors
25. The amino-terminal 29- and 72-kDa fragments of fibronectin mediate selective monocyte recruitment
26. Production and characterization of recombinant active mouse gelatinase B from eukaryotic cells and in vivo effects after intravenous administration
27. Metalloproteinases and their inhibitors in matrix remodeling
28. Leukoregulin, a T-cell derived cytokine, upregulates stromelysin-1 gene expression in human dermal fibroblasts: evidence for the role of AP-1 transcriptional activation
29. Loss of cell viability dramatically elevates cell surface plasminogen binding and activation
30. Relating matrix metalloproteinase structure to function: why the 'hemopexin' domain?
31. Matrix metalloproteinases 1, 2 and 3: substrate specificities and activation mechanisms
32. Activation mechanisms of the precursors of matrix metalloproteinases 1, 2 and 3
33. Fibronectin fragment(s) are chemotactic for human peripheral blood monocytes
34. Collagen and collagen peptide-induced chemotaxis of human blood monocytes
35. Chemotactic attraction of human fibroblasts to type I, II and III collagens and collagen-derived peptides
36. Fibronectin and its receptors
37. Activation of the 92-kDa gelatinase by stromelysin and 4-aminophenylmercuric acetate. Differential processing and stabilization of the carboxyl-terminal domain by tissue inhibitor of metalloproteinases (TIMP)
38. Immobilisation of monocytes to a solid support: a model for the study of ligand-binding interactions and plasminogen activation at the cell surface
39. Cyclosporin A inhibits collagenase gene expression via AP-1 and JNK suppression in human gingival fibroblasts
40. SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway
41. Components of the nuclear signaling cascade that regulate collagenase gene expression in response to integrin-derived signals
42. Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): mechanisms that control enzyme activity, transcription, and mRNA stability
43. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
44. Primary structure and function of stromelysin/transin in cartilage matrix turnover
45. Fibronectin fragments in osteoarthritic synovial fluid
46. Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysi