Cyclosporin A inhibits collagenase gene expression via AP-1 and JNK suppression in human gingival fibroblasts

Journal of Periodontal Research

Volumn 33, Issue 8, 1998, Pages 448-452

  Sugano, Naoyuki ^a   Ito, Koichi ^a   Murai, Seidai ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

Collagenase; Cyclosporin A; Fibroblast; Signal transduction

Indexed keywords

COLLAGENASE; CYCLOSPORIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; GINGIVA; GINGIVA OVERGROWTH; HUMAN; METABOLISM; SIGNAL TRANSDUCTION;

CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; COLLAGENASES; CYCLOSPORINE; DOWN-REGULATION; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GINGIVA; GINGIVAL OVERGROWTH; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEASE INHIBITORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 0032200714     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.1998.tb02343.x     Document Type: Article

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