The interaction of Na+ and K+ in the pore of cyclic nucleotide-gated channels

Biophysical Journal

Volumn 79, Issue 5, 2000, Pages 2475-2493

  Gamel, Katia ^a   Torre, Vincent ^a  

^a SISSA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CESIUM ION; CYCLIC NUCLEOTIDE; CYSTEINE; POTASSIUM ION; PROLINE; RUBIDIUM ION; SODIUM ION; THREONINE;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATTLE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CONFORMATIONAL TRANSITION; ION CONDUCTANCE; ION PERMEABILITY; NONHUMAN; OOCYTE; POTASSIUM CELL LEVEL; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; SODIUM CELL LEVEL; SODIUM CONDUCTANCE; SODIUM CURRENT; XENOPUS LAEVIS;

EID: 0033729116     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76490-3     Document Type: Article

References (40)

1. Adzhubei, A. A., and M. J. E. Sternberg. 1993. Left-handed polyproline II helices commonly occur in globular protein. J. Mol. Biol. 229:472-493.
2. Becchetti, A., K. Gamel, and V. Torre. 1999. Cyclic nucleotide-gated channels: pore topology studied through the accessibility of reporter cysteines. J. Gen. Physiol. 114:377-392.
3. Biel, M., X. Zong, and F. Hofmann. 1995. Molecular diversity of cyclic nucleotide-gated cation channels. Naunyn Schmiedebergs Arch. Pharmacol. 353(1):1-10.
4. Catterall, W. A. 1994. Molecular properties of a superfamily of plasma-membrane cation channels. Curr. Opin. Cell Biol. 6:607-615.
5. Creighton, T. E. 1993. Proteins: Structures and Molecular Properties. New York, Freeman Company, Inc.
6. + conduction and selectivity. Science. 280:69-77.
7. 2+ blockage and ionic selectivity. Proc. Natl. Acad. Sci. U.S.A. 91:1109-1113.
8. Finn, J. T., M. E. Grunwald, and K-W. Yau. 1996. Cyclic nucleotide-gated ion channels: an extended family with diverse functions. Anna. Rev. Physiol. 58:395-426.
9. Gordon, S. E., and W. N. Zagotta. 1995a. Localization of regions affecting an allosteric transition in cyclic nucleotide-activated channels. Neuron. 14:857-864.
10. 2+ in cyclic nucleotide-gated channels. Proc. Natl. Acad. Sci. USA. 92:10222-10226.
11. Goulding, E. H., G. R. Tibbs, D. Liu, and S. A. Siegelbaum. 1993. Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels. Nature. 364:61-64.
12. + channels. In Ion Channels and Genetic Diseases. New York, Rockfeller University Press. 1-16.
13. Hamill, O. P., A. Many, E. Neher, B. Sakmann, and F. J. Sigworth. 1981. Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391:85-100.
14. + channels. Science. 258:1152-1155.
15. Hille, B. 1992. Ionic Channels of Excitable Membranes. Sunderlands, MA, Sinauer Associates.
16. Jan, L. Y., and Y. N. Jan. 1990. A superfamily of ion channels. Nature. 345: 672-675.
17. Jan, L. Y., and Y. N. Jan. 1992. Tracing the roots of ion channels. Cell. 69:715-718.
18. Karpen, J. W., A. L. Zimmerman, L. Stryer, and D. A. Baylor. 1988. Gating kinetics of the cyclic GMP-activated channel of retinal rods: flash photolysis and voltage-jump studies. Proc. Natl. Acad. Sci. USA. 85:1287-1291.
19. Kaupp, U. B., T. Niidome, T. Tanabe, S. Terada, W. Bönigk, W. Stühmer, N. Cook, K. Kangawa, H. Matsuo, T. Hirose, and S. Numa. 1989. Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature. 342: 762-766.
20. Kaupp, U. B. 1995. Family of cyclic nucleotide-gated channels. Curr. Opin. Neurobiol. 14:434-442.
21. Laio, A., and V. Torre. 1999. Physical origin of selectivity in ionic channels of biological membranes. Biophys. J. 76:129-148.
22. Li, J., W. N. Zagotta, and H. A. Lester. 1997. Cyclic nucleotide-gated channels structural basis of ligand efficacy and allosteric modulation. Q. Rev. Biophys. 30:177-193.
23. Liu, D. T., G. R. Tibbs, and S. A. Siegelbaum. 1996. Subunit stoichiometry of cyclic nucleotide-gated channels and effects of subunit order on channel function. Neuron. 16:983-990.
24. Liu, D. T., G. R. Tibbs, P. Paoletti, and S. A. Siegelbaum. 1998. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers. Neuron. 21:235-248.
25. Menini, A. 1990. Currents carried by monovalent cations through cyclic GMP-activated channels in excised patches from salamander rods. J. Physiol. 424:167-185.
26. Menini, A. 1995. Cyclic nucleotide-gated channels in visual and olfactory transduction. Biophys. Chem. 55:185-196.
27. Nizzari, M., F. Sesti, M. T. Giraudo, C. Virginio, A. Cattaneo, and V. Torre. 1993. Single channel properties of a cloned channel activated by cGMP. Proc. R. Soc. Lond. 254:69-74.
28. Park, C. S., and R. MacKinnon. 1995. Divalent cation selectivity of an ion binding site in the pore of a cyclic nucleotide-gated channel. Biochemistry. 34:13328-13333.
29. Picco, C., and A. Menini. 1993. The permeability of the cGMP-activated channel to organic cations in retinal rods of the tiger salamander. J. Physiol. 460:741-758.
30. Root, M. J., and R. MacKinnon. 1993. Identification of an external divalent binding site in the pore of a cGMP-activated channel. Neuron. 11: 459-466.
31. Ruiz, M. L., and J. W. Karpen. 1999. Opening mechanism of a cyclic nucleotide-gated channel based on analysis of single channels locked in each liganded state. J. Gen. Physiol. 113:873-895.
32. Sesti, F., E. Eismann, U. B. Kaupp, M. Nizzari, and V. Torre. 1995. The multi-ion nature of the cGMP-gated channel from vertebrate rods. J. Physiol. 487:17-36.
33. Sesti, F., M. Nizzari, and V. Torre. 1996. Effect of changing temperature on the ionic permeation through the cyclic CMG-activated channel from vertebrate photoreceptors. Biophys. J. 70:2616-2639.
34. Sunderman, E. R., and W. N. Zagotta. 1999. Mechanisms of allosteric modulation of rod cyclic nucleotide-gated channels. J. Gen. Physiol. 113:601-619.
35. Tibbs, G. R., E. H. Goulding, and S. A. Siegelbaum. 1997. Allosteric activation and tuning of ligand efficacy in cyclic-nucleotide-gated channels. Nature. 386:612-615.
36. Varnum, M. D., and W. N. Zagotta. 1996. Subunit interaction in the activation of cyclic nucleotide-gated ion channels. Biophys. J. 70:2667-2679.
37. Varnum, M. D., and W. N. Zagotta. 1997. Interdomain interactions underlying activation of cyclic nucleotide-gated channels. Science. 278:110-113.
38. Zagotta, W. N. 1996. Molecular mechanisms of cyclic nucleotide-gated channels. J. Bioenerg. Biomembr. 28:269-278.
39. Zagotta, W. N., and S. A. Siegelbaum. 1996. Structure and function of cyclic nucleotide-gated channels. Annu. Rev. Neurosci. 19:235-263.
40. Zimmerman, A. L. 1995. Cyclic nucleotide-gated channels. Curr. Opin. Neurobiol. 5:296-303.