DNA methylation: Normal development, inherited diseases, and cancer

Journal of Clinical Ligand Assay

Volumn 23, Issue 2, 2000, Pages 144-146

  Ehrlich, M ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE;

BIRTH DEFECT; CONFERENCE PAPER; DEVELOPMENTAL GENETICS; DNA METHYLATION; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE MUTATION; GENETIC DISORDER; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; RETT SYNDROME;

EID: 0033711007     PISSN: 10811672     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (33)

1. Tissue-specific differences in DNA methylation in various mammals
2. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells
3. The RNA moiety of chick embryo 5-methylcytosine- DNA glycosylase targets DNA demethylation
4. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells: The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
5. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
6. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
7. Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression
8. Tissue-specific methylation occurs in the essential promoter element of the tyrosine hydroxylase gene
9. Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells
10. Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice
11. Tissue-specific transcriptional regulation of human leukosialin (CD43) gene is achieved by DNA methylation
12. Arole for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus
13. Regulation of Pdha-2 expression is mediated by proximal promoter sequences and CpG rnethylation
14. DNA methylation represses FMR-1 transcription in fragile X syndrome
15. In vitro reactivation of the FMR 1 gene involved in fragile X syndrome
16. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl- CpG-binding protein 2
17. An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome
18. ICF syndrome: A new case and review of the literature
19. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
20. The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
21. Preferential induction of chromosome I multibranched figures and wholeann deletions in a human pro-B cell line treated with 5-azacytidine or 5-azadeoxycytidine
22. DNA demethylation and pericentromeric rearrangements of chromosome 1
23. Chromosomal imbalance maps of malignant solid tumors: A cytogenetic survey of 3185 neoplasms
24. Satellite DNA hypomethylation vs overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential
25. Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16
26. Hypomethylation of pericentromeric DNA in breast adenocarcinomas
27. Cloning, expression and chromosome locations of the human DNMT3 gene family
28. The 5-methylcytosine content of DNA from human tumors
29. Reduced genomic 5-methylcytosine content in human colonic neoplasia
30. Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation
31. Human breast and colon cancers .exhibit alterations of DNA methylation patterns at several DNA segments on chromosomes 11p and 17p
32. Establishment of methylation-sensitiverepresentational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors
33. A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer