Effect of endothelin antagonists, including the novel ET(A) receptor antagonist LBL 031, on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways

British Journal of Pharmacology

Volumn 131, Issue 6, 2000, Pages 1129-1134

  Hele, Dave J ^a   Birrell, Mark A ^a   Webber, Stephen E ^b   Foster, Martyn L ^b   Belvisi, Maria G ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b Aventis Pharma Ltd   (United Kingdom)

Author keywords

Adult respiratory distress syndrome; Airways; Endothelin; Endothelin antagonists; Lipopolysaccharide; Microvascular leakage

Indexed keywords

4 (4 METHOXYPHENYL) 2 (3,4 METHYLENEDIOXYPHENYL) 4 OXO 3 (3,4,5 TRIMETHOXYBENZYL) 2 BUTENOIC ACID; BOSENTAN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; ENDOTHELIN RECEPTOR ANTAGONIST; LBL 031; LIPOPOLYSACCHARIDE; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; UNCLASSIFIED DRUG;

ADULT RESPIRATORY DISTRESS SYNDROME; AIRWAY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXUDATE; INFLAMMATORY DISEASE; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK;

EID: 0033696308     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703691     Document Type: Article

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