Activation of ETA receptors is partially responsible for the rapid increase in haematocrit induced by bacterial lipopolysaccharide in the rat

Life Sciences

Volumn 60, Issue 19, 1997, Pages PL271-PL276

  Allcock, Graham H ^a   Warner, Timothy D ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

endothelin; endothelin ETA receptors; haematocrit; lipopolysaccharide

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; LIPOPOLYSACCHARIDE; N ACETYL 10,11 DIHYDRO 5H DIBENZO[A,D]CYCLOHEPTEN 5 YLGLYCYLLEUCYLASPARTYLISOLEUCYLISOLEUCYLTRYPTOPHAN; AZEPINE DERIVATIVE; ENDOTHELIN RECEPTOR; INDOLE DERIVATIVE; OLIGOPEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ANTAGONISM; DRUG POTENTIATION; HEMATOCRIT; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; RAT; ANIMAL; BLOOD PRESSURE; DRUG EFFECT; METABOLISM; WISTAR RAT;

ANIMALS; AZEPINES; BLOOD PRESSURE; ENDOTHELIN-1; HEMATOCRIT; INDOLES; LIPOPOLYSACCHARIDES; MALE; OLIGOPEPTIDES; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN;

EID: 0030623940     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0024-3205(97)00116-1     Document Type: Article

References (20)

1. T. MASAKI, S. KIMURA, M. YANAGISAWA and K. GOTO, Circulation 84 1457-1468 (1991).
2. P. KLEMM, T.D. WARNER, T. HOHLFELD, R. CORDER and J.R VANE, Proc. Natl. Acad. Sci. (USA) 92 2691-2695 (1995).
3. E.F. SMITH III, M.J. SLIVJAK, J.O. BARTUS AND K.M. ESSER J. Cardiovasc. Pharmacol. 18 721-728 (1991).
4. R.S. ZIMMERMAN, A.J. MARTINEZ, M. MAYMIND and R.W. BARBEE, Circ. Res. 70 1027-1034 (1992).
5. D.M. POLLOCK, B.J. DIVISH and T.J. OPGENORTH J. Cardiovasc. Pharmacol. 22 (Suppl. 8) S295-S298 (1993).
6. P. NAMBI, M. PULLEN, M.J. SLIVJAK, E.H. OHLSTEIN, B. STORER and E.F. SMITH III, Pharmacology 48 147-156 (1994).
7. K. SOGABE, H. NIREI, M. SHOUBO, A. NOMOTO S. AO, Y. NOTSU and T. ONO, J. Pharmacol. Exp. Ther. 264 1040-1046 (1993).
8. W.L. CODY, A.M. DOHERTY, J.X. HE, P.L. DEPUE, S.T. RAPUNDALO, G.A. HINGORANI, T.C. MAJOR, R.L. PANEK, D.T. DUDLEY, S.J. HALEEN, D. LADOUCEUR, K.E. HILL, M.A. FLYNN and E. REYNOLDS, J. Med. Chem. 35 3301-3303 (1992).
9. S. NAKAMURA, M. NARUSE, K. NARUSE, H. DEMURA and H. UEMURA, Histochemistry 94 475-477 (1990).
10. H. MACARTHUR, T.D. WARNER, E.G. WOOD, R. CORDER and J.R. VANE, Biochem. Biophys. Res. Commun. 200 395-400 (1994).
11. S. VEMULAPALLI, P.J.S. CHUI, K. GRISCTI, A. BROWN, S. KUROWSKI, and E.J. SYBERTZ, Eur. J. Pharmacol. 257 95-102 (1994).
12. M.W. MACCUMBER, C.A. ROSS, B.M. GLASER and S.H. SNYDER Proc. Natl. Acad. Sci. (USA) 86 7285-7289 (1990).
13. S. NAKAMURA, M. NARUSE, K. NARUSE, S. SHIODA, Y. NAKAI, and H. UEMURA Endocrinology 132 530-533 (1993).
14. H. KAUFMANN, E. ORIBE and J.A. OLIVER, Lancet 338 1542-1545 (1991).
15. H. OKUMURA, N. ASHIZAWA, F. KOBAYASHI, K. ARAI, R. ASAKURA, N. ASHIKAWA, and M. MATSUURA, Br. J. Pharmacol. 110 1395-1400 (1993).
16. M.G. SIROIS, J.G. FILEP, A. ROUSSEAU, A. FOURNIER, G.E. PLANTE and P. SIROIS Eur. J. Pharmacol. 214 119-125 (1992).
17. J.G. FILEP, M.G. SIROIS, A. ROUSSEAU, A. FOURNIER and P. SIROIS, Br. J. Pharmacol. 104 797-804 (1991).
18. L. BARANYI, W. CAMPBELL, K. OHSHIMA, S. FUJIMOTO, M. BOROS and H. OKADA, Nature Med. 1 894-901 (1995).
19. T.W. DOEBBER, M.S. WU, J.C. ROBBINS, B.M. CHOY, M.N. CHANG, and T.Y. SHEN, Biochem. Biophys. Res. Commun. 129 799-808 (1995).
20. D.A. HANDLEY, R.G. VAN VALEN, M.K. MELDEN and R.N. SAUNDERS Thromb. Haemostasis 52 34-36 (1984).