Increased levels of interleukin-18 in patients with pulmonary sarcoidosis

American Journal of Respiratory and Critical Care Medicine

Volumn 162, Issue 5, 2000, Pages 1979-1982

  Shigehara, K ^a   Shijubo, N ^a   Ohmichi, M ^a   Yamada, G ^a   Takahashi, R ^a   Okamura, H ^a   Kurimoto, M ^a   Hiraga, Y ^a   Tatsuno, T ^a   Abe, S ^a   Sato, N ^a  

^a Hokkaido Br of the Anti TB Assoc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18; LYSOZYME;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIAGNOSTIC VALUE; DISEASE ACTIVITY; ENZYME ACTIVITY; FEMALE; HUMAN; LUNG LAVAGE; LYMPHOCYTE; MALE; PRIORITY JOURNAL; SARCOIDOSIS;

EID: 0033679553     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.162.5.9911113     Document Type: Article

References (20)

1. Statement on sarcoidosis
2. Sarcoidosis: Immunopathogenetic concepts and their clinical application
3. The expanding universe of T-cell subsets: Th1, Th2 and more
4. Cloning of a new cytokine that induces IFN-γ production by T cells
5. IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family
6. Interferon-γ inducing factor, novel cytokine, enhances Fas ligand-mediated cytotoxicity of murine T helper cells
7. Progastrin-releasing peptide (31-98) in idiopathic pulmonary fibrosis and sarcoidosis
8. Characterization of antihuman interleukin-18 (IL-18)/interferon-γ-inducing factor (IGIF) monoclonal antibodies and their application in the measurement of human IL-18 by ELISA
9. Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type I and cytotoxic lymphocytes
10. Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis
11. Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia
12. Detection of endogenous cytokines in sera or in lymph nodes obtained from patients with sarcoidosis
13. Serum interleukin 12 concentration in juvenile chronic arthritis
14. IL-12 and IL-18 enhance interferon-γ production in bronchoalveolar lavage cells of patients with sarcoidosis
15. Amounts of angiotensin-converting enzyme mRNA reflect the burden of granulomas in granulomatous lung disease
16. Deletion polymorphism in the angiotensin I converting enzyme (ACE) gene as a genetic risk factor for sarcoidosis
17. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
18. A proinflammatory role for IL-18 in rheumatoid arthritis
19. Interleukin-18, interferon-gamma, IP-10 and Mig expression in Epstein-Barr virus-induced infectious mononucleosis and posttransplant lymphoproliferative disease
20. Overesecretion of IL-18 in haemophagocytic lymphohistiocytosis: A novel marker of disease activity