Deletion polymorphism in the angiotensin I converting enzyme (ACE) gene as a genetic risk factor for sarcoidosis

Thorax

Volumn 51, Issue 8, 1996, Pages 777-780

  Furuya, Ken ^a   Yamaguchi, Etsuro ^a   Itoh, Akihide ^a   Hizawa, Nobuyuki ^a   Ohnuma, Noritomo ^a   Kojima, Junichiro ^a   Kodama, Natsuko ^a   Kawakami, Yoshikazu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

ACE gene polymorphism; angiotensin I converting enzyme (ACE); sarcoidosis

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DNA;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SARCOIDOSIS;

EID: 0029810906     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.51.8.777     Document Type: Article

References (25)

1. Lieberman J. Elevation of serum angiotensin-converting-enzyme (ACE) level in sarcoidosis. Am J Med 1975; 59:365-72.
2. Fraser RG, Paré JAP, Paré PD, Fraser RS, Genereux GP. Pulmonary disease of unknown origin. In: Bralow L, ed. Diagnosis of diseases of the chest. 3rd ed. Philadelphia: WB Saunders, 1991:2604-711.
3. Lieberman J, Nosal A, Schlessner L A, Sastre-Foken A. Serum angiotensin-converting enzyme for diagnosis and therapeutic evaluation of sarcoidosis. Am Rev Respir Dis 1979;120:329-35.
4. Neels HM, Scharpe SL, Van Sande ME, Vervek RM, Van Acker KJ. Improved micromethod for assay of serum angiotensin converting enzyme. Clin Chem 1982;28:1352-5.
5. Silberstein LE, Berkman LE, Fanburg BL. Angiotensin-I-converting enzyme (ACE) activity in serum following plasma exchange. Proc Soc Exp Biol Med 1983;173:222-6.
6. Fogarty Y, Fraser CG, Browning MCK. Intra- and inter-individual variation of serum angiotensin converting enzyme. Clinical implications. Ann Clin Biochem 1989; 26:201-2.
7. Cambien F, Alhenc-Gelas F, Herbeth B, Andre JL, Rakotovao R, Gonzales MF, et al. Familial resemblance of plasma angiotensin-converting enzyme level. The Nancy study. Am J Hum Genet 1988;43:774-80.
8. Soubrier F, Alhenc-Gelas F, Hubert C, Allegrini J, John M, Tregear G, et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci U S A 1988;85:9386-90.
9. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990;86:1343-6.
10. Kasahara Y, Ashihira Y. Colorimetry of angiotensin-I converting enzyme activity in serum. Clin Chem 1981; 27:1922-5.
11. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase I). Nucleic Acids Res 1992;20:1433.
12. Furuya K, Yamaguchi E, Hirabayashi T, Itoh A, Hizawa N, Ohnuma N, et al. Angiotensin-I-converting enzyme gene polymorphism and susceptibility to cough. Lancet 1994; 343:354.
13. Cambien F, Poirier O, Lecerf I, Evans A, Cambou JP, Arveiler D, et al. Deletion polymorphism in the the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992;359:641-4.
14. Mayock RI., Bertrand P, Morrison CE, Scott JH. Manifestations of sarcoidosis. Analysis of 145 patients, with a review of nine series selected from the literature. Am J Med 1996;35:67-89.
15. Bloem LJ, Manatunga AK, Boatright E, Pratt JH. Relation of race and a polymorphism in the angiotensin I-converting enzyme gene to enzyme levels (abstract). Hypertension 1993;22:407.
16. Lee EJ. Population genetics of the angiotensin-converting enzyme in Chinese. Br J Clin Pharmacol 1994;37;212-4.
17. Da Costa JL. Geographic epidemiology of sarcoidosis in southeast Asia. Am Rev Respir Dis 1973;108:1269-72.
18. Pertschuk LP, Silverstein E, Friedland J. Immunohistologic diagnosis of sarcoidosis: detection of angiotensin-converting enzyme in sarcoid granulomas, Am J Clin Pathol 1981;75:350-4.
19. Okabe T, Yamagata K, Fujisawa M, Watanabe J, Takaku F. Increased angiotensin-converting enzyme in peripheral blood monocytes from patients with sarcoidosis. J Clin Invest 1985;75:911-4.
20. Costerousse O, Allegrini J, Lopez M, Alhenc-Gelas F. Angiotensin I-converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes. Biochem J 1993;290:33-40.
21. Weinstock JV, Kassab J. Chemotactic response of splenic mononuclear cells to angiotensin II in murine schistosomiasis. J Immunol 1986;137:2020-4.
22. Weinstock JV, Blum AM, Kassab J T. Angiotensin II is chemotactic for a T-cell subset which can express migration inhibition factor activity in murine schistosomiasis mansoni. Cell Immunol 1987;107:180-7.
23. Kozlowski S, Corr M, Takeshita T, Boyd LF, Pendleton CD, Germain RN, et al. Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules. J Exp Med 1992; 175:1417-22.
24. Kozlowski S, Corr M, Shirai M, Boyd LF, Pendleton CD, Berzofsky JA, et al. Multiple pathways are involved in the extracellular processing of MHC class I-restricted peptides. J Immunol 1993;151:4033-44.
25. Sherman LA, Burke TA, Biggs J. A. Extracellular processing of peptide antigens that bind class I major histocompatibility molecules. J Exp Med 1992;175:1221-6.