Serum interleukin 12 concentration in juvenile chronic arthritis

Annals of the Rheumatic Diseases

Volumn 57, Issue 7, 1998, Pages 425-428

  Gattorno, M ^a   Picco, P ^a   Vignola, S ^a   Stalla, F ^a   Buoncompagni, A ^a   Pistoia, V ^a  

^a G GASLINI INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12;

ARTICLE; CHILD; DIAGNOSTIC VALUE; DISEASE SEVERITY; FEMALE; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; SERODIAGNOSIS;

EID: 0031824303     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.57.7.425     Document Type: Article

References (22)

1. Panayi GS, Lanchbury JS, Kingsley GH. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992;35:729-35.
2. Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996;383:787-94.
3. Del Prete GF, De Carli M, Mastromauro C, Biagiotti R, Macchia S, Falagiani P, et al. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposing (type I T helper and type II T helper) profiles of cytokine production. J Clin Invest 1991; 8:346-50.
4. Haanen JBAG, deWaal Malefijt R, Res PCM, Kraakman EM, Ottenhoff THM, deVries RRP, et al. Selection of human T helper type I-like T cell subset in mycobacteria. J Exp Med 1991;174:583-92.
5. Salgame P, Abrams JS, Clayberger C, Goldstein H, Convi J, Modlin RL, et al. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 1991;254:274-81.
6. Del Prete GF, Maggi E, Parronchi P, Chretien I, Tiri A, Macchia D, et al. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988;140:4193-203.
7. Trincheri G. Interleukin 12: a cytokine produced by antigen presenting cells with immunoregolatory functions in the generation of T-helper cells type I and cytotoxic lymphocytes. Blood 1994;84:4008-27.
8. Manetti R, Gerosa F, Giudizi MG, Biagiotti R, Paronchi P, Piccinni M, et al. Interleukin-12 induces stable priming for interferon-γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 cell clones. J Exp Med 1994;179:1273-83.
9. Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trincheri G, et al. Natural killer cell stimulatory factor (interleukin 12, IL-12) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing Th cells. J Exp Med 1993;177:1199-204.
10. Simon AK, Seipelt E, Sieper J. Divergent T cell cytokine pattern in inflammatory arthritis. Proc Natl Acad Sci USA 1994;91:8562-6.
11. Dolhain RJEM, van der Heiden AN, ter Haar NT, Breedveld FC, Miltenburg AMM. Shift toward T lymphocytes with a T helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis. Arthritis Rheum 1996; 39;12:1961-9.
12. Gattorno M, Facchetti P, Ghiotto F, Vignola S, Buoncompagni A, Prigione I, et al. Synovial fluid T cell clones from oligoarticular juvenile arthritis patients display a prevalent Th1/Th0 patterns of cytokine secretion irrespective to immunophenotype. Clin Exp Immunol 1997;109:4-14.
13. European League Against Rheumatism (EULAR): Bulletin 4. Nomenclature and classification of arthritis in children. Basel: National Zeitung AG, 1977.
14. Ravelli A, Viola S, Ruperto N, Corsi B, Ballardini G, Martini A. Correlation between conventional disease activity measures in juvenile chronic arthritis. Ann Rheum Dis 1997;56:197-200.
15. Southwood TR, Malleson PN. The clinical history and physical examination. In: Southwood TR, Malleson PN, eds. Arthritis in children and adolescents. Clinical paediatrics. London: Bailliere Tindall, 1993:637-64.
16. Fantini F, Corvaglia G, Bergomi P, Gattinara M, Gerloni V, Lomater C, et al. Validation of the italian version of the Stanford Chilhood health assessment questionnaire for measuring functional status in children with chronic arthritis. Clin Exp Rheum 1995;13:785-91.
17. Trembleau S, Penna G, Bosi E, Mortara A, Gately MK, Adorini L. IL-12 administration induces Th1 and accelerate autoimmune diabetes in NOD mice. J Exp Med 1995; 181:817-21.
18. McIntyre KW, Shuster DJ, Gillooly KM, Warrier RR, Connaughton SE, Hall LB, et al. Reduced incidence and severity of collagen-induced arthritis in interelukin-12-deficent mice. Eur J Immunol 1996;26:2933-8.
19. Bucht A, Larsson P, Weisbrot L, Thorne C, Pisa P, Smedegard G, Keystone EC, et al. Expression of interferon-gamma (IFN-γ), IL-10, IL-12 and transforming growth factor-beta (TGF-β) mRNA in synovial fluid cells from patients in the early and late phases of rheumatoid arthritis (RA). Clin Exp Immunol 1996;103:357-67.
20. Cope AP, Aderka D, Doherty M, Engelmann H, Gibbons DL, Jones AC, et al. Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases. Arthritis Rheum 1992; 35:1160-9.
21. Gattorno M, Picco P, Buoncompagni A, Stalla F, Facchetti P, Sormani MP, et al. Serum p55 and p75 tumour necrosis factor receptors as markers of disease activity in juvenile chronic arthritis. Ann Rheum Dis 1996;55:243-7.
22. Manetti R, Gerosa F, Giudizi MG, Biagiotti R, Paronchi P, Piccinni P, et al. Interleukin 12 induces stable priming for interferon-γ (IFN-γ) production during differentiation of human T helper (Th) cells and transient IFN-γ production in established Th2 cell clones. J Exp Med 1994;179:1273-83.