4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor

Journal of Medicinal Chemistry

Volumn 40, Issue 15, 1997, Pages 2374-2385

  Rowley, Michael ^a   Collins, Ian ^a   Broughton, Howard B ^a   Davey, William B ^a   Baker, Raymond ^a   Emms, Frances ^a   Marwood, Rosemarie ^a   Patel, Shil ^a   Patel, Smita ^a   Ragan, C Ian ^a   Freedman, Stephen B ^a   Ball, Richard ^b   Leeson, Paul D ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 CHLOROPHENYL) 3 [1 (4 CHLOROBENZYL)PIPERIDIN 4 YL]PYRAZOLE; 5 (4 CHLOROPHENYL) 4 METHYL 3 [1 (2 PHENYLETHYL)PIPERIDIN 4 YL]ISOXAZOLE; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; HETEROCYCLIC COMPOUND; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DRUG BIOAVAILABILITY; DRUG BRAIN LEVEL; DRUG HALF LIFE; DRUG PENETRATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HUMAN; HUMAN CELL; NONHUMAN; RECEPTOR AFFINITY; SCHIZOPHRENIA; STRUCTURE ACTIVITY RELATION;

CELL LINE; HUMANS; LIGANDS; PIPERIDINES; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4;

EID: 15144357943     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970111h     Document Type: Article

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