2-Phenyl-4(5)-[[4-(pyrimidin-2-yl)piperazin-1-yl]methyl]imidazole. A highly selective antagonist at cloned human D4 receptors

Journal of Medicinal Chemistry

Volumn 40, Issue 1, 1997, Pages 1-3

  Thurkauf, A ^a   Yuan, J ^a   Chen, X ^a   Xiao Shu He, ^a   Wasley, J W F ^a   Hutchison, A ^a   Woodruff, K H ^a   Meade, R ^a   Hoffman, D C ^a   Donovan, H ^a   Jones Hertzog, D K ^a  

^a NEUROGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYL 4 [[4 (2 PYRIMIDINYL)PIPERAZIN 1 YL]METHYL]IMIDAZOLE; CLOZAPINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; RECEPTOR AFFINITY; RECEPTOR DENSITY; SCHIZOPHRENIA;

ANTIPSYCHOTIC AGENTS; CLOZAPINE; HUMANS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4;

EID: 17344375725     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960637m     Document Type: Article

References (13)