A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils

Nature Structural Biology

Volumn 7, Issue 12, 2000, Pages 1095-1099

  Fezoui, Youcef ^a   Hartley, Dean M ^a   Walsh, Dominic M ^a   Selkoe, Dennis J ^a   Osterhout, John J ^b   Teplow, David B ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; CONGO RED; HELIX LOOP HELIX PROTEIN; MONOMER; PROTEINASE;

AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BRAIN CELL; CYTOTOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN SECONDARY STRUCTURE; PROTEIN SYNTHESIS; RAT;

AMINO ACID SEQUENCE; ANIMALS; BIOPOLYMERS; CELL DEATH; CELLS, CULTURED; CIRCULAR DICHROISM; CONGO RED; ELECTROSTATICS; ENDOPEPTIDASE K; FORMAZANS; HELIX-TURN-HELIX MOTIFS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURONS; PC12 CELLS; PEPTIDES; PROTEIN CONFORMATION; RATS; SENILE PLAQUES; TETRAZOLIUM SALTS;

ANIMALIA;

EID: 0033669788     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/81937     Document Type: Article

References (31)