Subcellular post-transcriptional targeting: Delivery of an intracellular protein to the extracellular leaflet of the plasma membrane using a glycosyl-phosphatidyl inositol (GPI) membrane anchor in neurons and polarised epithelial cells

Gene Therapy

Volumn 7, Issue 22, 2000, Pages 1947-1953

  Brown, O ^a   Cowen, R L ^a   Preston, C M ^b   Castro, M G ^a   Lowenstein, P R ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INSTITUTE OF VIROLOGY   (United Kingdom)

Author keywords

Herpes simplex vectors; Neuronal polarity; Targeting; Viral vectors

Indexed keywords

CELL MEMBRANE PROTEIN; CELL PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL; PRODRUG; RECOMBINANT PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CELL KILLING; CELL MEMBRANE; CELL POLARITY; CONTROLLED STUDY; DRUG TARGETING; ENDOPLASMIC RETICULUM; EPITHELIUM CELL; GENE CONSTRUCT; GENE TRANSFER; GENETIC CODE; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS 1; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TARGET CELL; TEMPERATURE SENSITIVE MUTANT; TRANSGENE;

ANIMALIA; DNA VIRUSES; HERPES; HUMAN HERPESVIRUS 1;

EID: 0033665673     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301325     Document Type: Article

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