Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: Reduced cytotoxicity of a truncated HSV1-TK

Gene Therapy

Volumn 7, Issue 8, 2000, Pages 679-685

  Cowsill, C ^a   Southgate, T D ^a   Morrissey, G ^a   Dewey, R A ^a   Morelli, A E ^a   Maleniak, T C ^a   Forrest, Z ^a   Klatzmann, D ^b   Wilkinson, G W G ^c   Lowenstein P R ^a   Castro, M G ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b Unit of Dermatology   (France)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Brain tumours; Cytotoxicity; Flow cytometry; Neurological; Thymidine kinase

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; VIRUS VECTOR;

ADENOVIRUS; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CELL GROWTH; CONTROLLED STUDY; CORPUS STRIATUM; CYTOTOXICITY; EDEMA; ENCEPHALITIS; GENE DOSAGE; GENE THERAPY; GLIA; GLIOMA; HERPES SIMPLEX VIRUS 1; MYELINATED NERVE; NERVE CELL; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR CELL; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

EID: 0034018533     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301147     Document Type: Article

References (17)