Patterning the early sea urchin embryo

Current Topics in Developmental Biology

Volumn 50, Issue , 2000, Pages 1-44

  Ettensohn, Charles A ^a   Sweet, Hyla C ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; AXIS; BIOLOGICAL MODEL; GENE EXPRESSION; MORPHOGENESIS; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; SEA URCHIN;

ANIMALS; AXIS; BODY PATTERNING; GENE EXPRESSION; MODELS, BIOLOGICAL; SEA URCHINS;

EID: 0033649018     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0070-2153(00)50002-7     Document Type: Review

References (198)

1. Aberle H. Bauer A. Stappert J. Kispert A. Kemler R. β-Catenin is a target for the ubiquitin-proteasome pathway EMBO J. 16 1997 3797 3804
2. Angerer L.M. Angerer R.C. Regulative development of the sea urchin embryo: Signaling cascades and morphogen gradients Semin. Cell Dev. Biol. 10 1999 327 334
3. Angerer L.M. Angerer R.C. Animal-vegetal patterning mechanisms in the early sea urchin embryo Dev. Biol. 218 2000 1 12
4. Angerer L.M. Dolecki G.J. Gagnon M.L. Lum R. Wang G. Yang Q. Humphreys T. Angerer R.C. Progressively restricted expression of a homeo☐ gene within the aboral ectoderm of developing sea urchin embryos Genes Dev. 3 1989 370 383
5. Angerer L.M. Oleksyn D. Logan C.Y. McClay D.R. Dale L. Angerer R.C. A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis Development 127 2000 1105 1114
6. Angerer R.C. Angerer L.M. Fate specification along the sea urchin embryo animal-vegetal axis Biol. Bull. 192 1997 175 177
7. Angerer R.C. Reynolds S.D. Grimwade J. Hurley D.L. Yang Q. Kingsley P.D. Gagnon M.L. Palis J. Angerer L.M. Contributions of the spatial analysis of gene expression to the study of sea urchin development Harris N. Williams D.G. In Situ Hybridisation: Application to Developmental Biology 1990 Cambridge Univ. Press Cambridge, UK 69 95
8. Artavanis-Tsakonas S. Rand M.D. Lake R.J. Notch signaling: Cell fate control and signal integration in development Science 284 1999 770 776
9. Benink H. Wray G. Hardin J. Archenteron precursor cells can organize secondary axial structures in the sea urchin embryo Development 124 1997 3461 3470
10. Benson S.C. Sucov H.M. Stephens L. Davidson E.H. Wilt F.H. A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule. I. Authentication of the cloned gene and its developmental expression Dev. Biol. 120 1987 499 506
11. Burke R.D. Echinoderm metamorphosis: comparative aspects of the change in form Jangoux M. Lawrence J. Echinoderm Studies 1989 A. A. Balkema Pub. Rotterdam 81 108
12. Calzone F.J. Hoog C. Teplow D.B. Cutting A.E. Zeller R.W. Britten R.J. Davidson E.H. Gene regulatory factors of the sea urchin embryo. I. Purification by affinity chromatography and cloning of P3A2, a novel DNA binding protein Development 112 1991 335 350
13. Calzone F.J. Thézé N. Thiebaud P. Hill R.L. Britten R.J. Davidson E.H. Developmental appearance of factors that bind specifically to cis-regulatory sequences of a gene expressed in the sea urchin embryo Genes Dev. 2 1988 1074 1088
14. Cameron R.A. Fraser S.E. Britten R.J. Davidson E.H. The oral-aboral axis of a sea urchin embryo is specified by first cleavage Development 106 1989 641 647
15. Cameron R.A. Britten R.J. Davidson E.H. The embryonic ciliated band of the sea urchin, Strongylocentrotus purpuratus , derives from both oral and aboral ectoderm territories Dev. Biol. 160 1993 369 376
16. Cameron R.A. Leahy P.S. Davidson E.H. Twins raised from separated blastomeres develop into sexually mature Strongylocentrotus purpuratus Dev. Biol. 178 1996 514 519
17. Chan S.-M. Xu N. Niemeyer C.C. Bone J.R. Flytzanis C.N. SpCOUP-TF: A sea urchin member of the steroid/thyroid hormone receptor family Proc. Natl. Acad. Sci. USA 89 1992 10568 10572
18. Chen S.W. Wessel G.M. Endoderm differentiation in vitro identifies a transitional period for endoderm ontogeny in the sea urchin embryo Dev. Biol. 175 1996 57 65
19. Coffman J.A. Kirchhamer C.V. Harrington M.G. Davidson E.H. SpRunt-1, a new member of the runt-domain family of transcription factors, is a positive regulator of the aboral ectoderm-specific CyIIIa gene in sea urchin embryos Dev. Biol. 174 1996 43 54
20. Coffman J.A. Kirchhamer C.V. Harrington M.G. Davidson E.H. SpMyb functions as an intramodular repressor to regulate spatial expression of CyIIIa in sea urchin embryos Development 124 1997 4717 4727
21. Coffman J.A. McClay D.R. A hyaline layer protein that becomes localized to the oral ectoderm and foregut of sea urchin embryos Dev. Biol. 140 1990 93 104
22. Cox K.H. Angerer L.M. Lee J.J. Davidson E.H. Angerer R.C. Cell lineage-specific programs of expression of multiple actin genes during sea urchin embryogenesis J. Mol. Biol. 188 1986 159 172
23. Czihak G. Echinoids Reverberi G. Experimental Embryology of Marine and Freshwater Invertebrates 1971 North-Holland Amsterdam 363 506
24. Dale L. Slack J.M.W. Regional specificity within the mesoderm of early embryos of Xenopus laevis Development 100 1987 279 295
25. Dan K. Tanaka Y. Attachment of one spindle pole to the cortex in unequal cleavage Ann. N.Y. Acad. Sci. 582 1990 108 119
26. Davidson E.H. Gene Activity in Early Development 3rd ed. 1986 Academic Press New York
27. Davidson E.H. Lineage-specific gene expression and the regulative capacities of the sea urchin embryo Development 105 1989 421 445
28. Davidson E.H. Cameron R.A. Ransick A. Specification of cell fate in the sea urchin embryo: Summary and some proposed mechanisms Development 125 1998 3269 3290
29. DeRobertis E.M. Sasai Y. A common plan for dorsoventral patterning in Bilateria Nature 380 1996 27 40
30. DiBernardo M. Castagnetti S. Bellomonte D. Oliveri P. Melfi R. Palla F. Spinelli G. Spatially restricted expression of P10tp, a Paracentrotus lividus orthopedia-related homeo☐ gene, is correlated with oral ectodermal patterning and skeletal morphogenesis in late-cleavage stage embryos Development 126 1999 2171 2179
31. DiBernardo M. Russo R. Oliveri P. Melfi R. Spinelli G. Homeo☐-containing gene transiently expressed in a spatially restricted pattern in the early sea urchin embryo Proc. Natl. Acad. Sci. USA 92 1995 8180 8184
32. DiCarlo M. Romancino D.P. Montana G. Ghersi G. Spatial distribution of two maternal messengers in Paracentrotus lividus during oognesis and embryogenesis Proc. Natl. Acad. Sci. USA 91 1994 5622 5626
33. Duncan L. Alper S. Arigoni F. Losick R. Stragier P. Activation of cell-specific transcription by a serine phosphatase at the site of asymmetric division Science 270 1995 641 644
34. Emily-Fenouil F. Ghiglione C. Lhomond G. Lepage T. Gache C. GSKβ/shaggy mediates patterning along the animal-vegetal axis of the sea urchin embryo Development 125 1998 2489 2498
35. Ettensohn C.A. Cell interactions and mesodermal cell fates in the sea urchin embryo Development 1992 43 51 (Suppl.)
36. Ettensohn C.A. Cell movements in the sea urchin embryo Curr. Opin. Gen. Dev. 9 1999 461 465
37. Ettensohn C.A. Guss K.A. Hodor P.G. Malinda K.M. The morphogenesis of the skeletal system of the sea urchin embryo Collier J.R. Reproductive Biology of Invertebrates 1997 Oxford and IBM Publishing Co. New Delhi
38. Ettensohn C.A. McClay D.R. Cell lineage conversion in the sea urchin embryo Dev. Biol. 125 1988 396 409
39. Eyal-Giladi H. Establishment of the axis in chordates: Facts and speculations Development 124 1997 2285 2296
40. Flytzanis C.N. Bogosian E.A. Niemeyer C.C. Expression and structure of the CyIIIb actin gene of the sea urchin Strongylocentrotus purpuratus Mol. Reprod. Dev. 1 1989 208 218
41. Franks R.R. Anderson R. Moore F.G. Hough-Evans B.R. Britten R.J. Davidson E.H. Competitive titration in living sea urchin embryos of regulatory factors required for expression of the CyIIIa actin gene Development 110 1990 31 40
42. Gagnon M.L. Angerer L.M. Angerer R.C. Posttranscriptional regulation of ectoderm-specific gene expression in early sea urchin embryos Development 114 1992 457 467
43. Gambino R. Romancino D.P. Cervello M. Vizzini A. Isola M.G. Virruso L. Di Carlo M. Spatial distribution of collagen type I mRNA in Paracentrotus lividus eggs and embryos Biochem. Biophys. Res. Commun. 238 1997 334 337
44. Gan L. Klein W.H. A positive cis-regulatory element with a bicoid target site lies within the sea urchin Spec2a enhancer Dev. Biol. 157 1993 119 132
45. Gan L. Mao C.-A. Wikramanayake A. Angerer L.M. Angerer R.C. Klein W.H. An orthodenticle-related protein from Srongylocentrotus purpuratus Dev. Biol. 167 1995 517 528
46. Gan L. Wessel G.M. Klein W. Regulatory elements from the related Spec genes of Strongylocentrotus purpuratus yield different spatial patterns with a lacZ reporter gene Dev. Biol. 142 1990 346 359
47. Gan L. Zhang W. Klein W. Repetitive DNA sequences linked to the sea urchin Spec genes contain transcriptional enhancer-like elements Dev. Biol. 139 1990 166 196
48. Ghiglione C. Emily-Fenouil F. Chang P. Gache C. Early gene expression along the animal-vegetal axis in sea urchin embryoids and grafted embryos Development 122 1996 3067 3074
49. Ghiglione C. Emily-Fenouil F. Lhomond G. Gache C. Organization of the proximal promoter of the hatching-enzyme gene, the earliest zygotic gene expressed in the sea urchin embryo Eur. J. Biochem. 250 1997 502 513
50. + of two zygotic genes during sea urchin early development EMBO J. 12 1993 87 96
51. Gibson A.W. Burke R.D. The origin of pigment cells in embryos of the sea urchin Strongylocentrotus purpuratus Dev. Biol. 107 1985 414 419
52. Goldstein B. Freeman G. Axis specification in animal development BioEssays 19 1997 105 116
53. Grimwade J.E. Gagnon M.L. Yang Q. Angerer R.C. Angerer L.M. Expression of two mRNAs encoding EGF-related proteins identifies subregions of sea urchin embryonic ectoderm Dev. Biol. 143 1991 44 57
54. Guss K.A. Ettensohn C.A. Skeletal morphogenesis in the sea urchin embryo: Regulation of primary mesenchyme gene expression and skeletal rod growth by ectoderm-derived cues Development 124 1997 1899 1908
55. Han M. Gut reaction to Wnt signaling in worms Cell 90 1997 581 584
56. Harada Y. Akasaka K. Shimada H. Peterson K.J. Davidson E.H. Satoh N. Spatial expression of a forkhead homologue in the sea urchin embryo Mech. Dev. 60 1996 163 173
57. Harada Y. Yasuo H. Satoh N. A sea urchin homologue of the chordate Brachyury (T) gene is expressed in the secondary mesenchyme founder cells Development 121 1995 2747 2754
58. Hardin J. Armstrong N. Short-range cell-cell signals control ectodermal patterning in the oral region of the sea urchin embryo Dev. Biol. 182 1997 134 149
59. Hardin J. Coffman J.A. Black S.D. McClay D.R. Commitment along the dorsoventral axis of the sea urchin embryo is altered in response to NiCl2 Development 116 1992 671 685
60. Hardin P.E. Angerer L.M. Hardin S.H. Angerer R.C. Klein W.H. The Spec2 genes of Strongylocentrotus purpuratus : Structure and differential expression in embryonic aboral ectoderm cells J. Mol. Biol. 202 1988 417 431
61. Harkey M.A. Klueg K. Sheppard P. Raff R.A. Structure, expression, and extracellular targetting of PM27, a skeletal protein associated specifically with growth of the sea urchin larval spicule Dev. Biol. 168 1995 549 566
62. Harkey M.A. Whiteley H.R. Whiteley A.H. Coordinate accumulation of five transcripts in the primary mesenchyme during skeletogenesis in the sea urchin embryo Dev. Biol. 125 1988 381 395
63. Harkey M.A. Whiteley H.R. Whiteley A.H. Differential expression of the msp130 gene among skeletal lineage cells in the sea urchin embryo: A three dimensional in situ hybridization analysis Mech. Dev. 37 1992 173 184
64. Harland R. Gerhart J. Formation and function of Spemann's organizer Annu. Rev. Cell Dev. Biol. 13 1997 611 667
65. Harrington M.G. Coffman J.A. Calzone F.J. Hood L.E. Britten R.J. Davidson E.H. Complexity of sea urchin nuclear proteins that contain basic domains Proc. Natl. Acad. Sci. USA 89 1992 6252 6256
66. Hart M.J. de los Santos R. Albert I.N. Rubinfeld B. Polakis P. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSKβ Curr. Biol. 8 1998 573 581
67. Heasman J. Patterning the Xenopus blastula Development 124 1997 4179 4191
68. Henry J.J. The development of dorsoventral and bilateral axial properties in sea urchin embryos Semin. Cell Dev. Biol. 9 1998 43 52
69. Henry J.J. Amemiya S. Wray G.A. Raff R.A. Early inductive interactions are involved in restricting cell fates of mesomeres in sea urchin embryos Dev. Biol. 136 1989 140 153
70. Henry J.J. Klueg K.M. Raff R.A. Evolutionary dissociation between cleavage, cell lineage and embryonic axes in sea urchin embryos Development 114 1992 931 938
71. Henry J.J. Raff R.A. Evolutionary change in the process of dorsoventral axis determination in the direct developing sea urchin, Heliocidaris erythrogramma Dev. Biol. 141 1990 55 69
72. Henry J.J. Raff R.A. Progressive determination of cell fate along the dorsoventral axis in the sea urchin Heliocidaris erythrogramma Roux's Arch. Dev. Biol. 204 1994 62 69
73. Holy J. Schatten G. Differential behavior of centrosomes in unequally dividing blastomeres during fourth cleavage of sea urchin embryos J. Cell Sci. 98 1991 423 431
74. Hoppler S. Brown J.D. Moon R.T. Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos Genes Dev. 10 1996 2805 2817
75. Hörstadius S. Experimental Embryology of Echinoderms 1973 Clarendon Press Oxford
76. Hough-Evans B.R. Franks R.R. Cameron R.A. Britten R.J. Davidson E.H. Correct cell type-specific expression of a fusion gene injected into sea urchin eggs Dev. Biol. 121 1987 576 579
77. Hough-Evans B.R. Franks R.R. Zeller R.W. Britten R.J. Davidson E.H. Negative spatial regulation of the lineage-specific CyIIIa actin gene in the sea urchin embryo Development 110 1990 41 50
78. Ikeda S. Kishida S. Yamamoto H. Murai H. Koyama S. Kikuchi A. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin EMBO J. 17 1998 1371 1384
79. Iuchi Y. Morokuma J. Akasaka K. Shimada H. Detection and characterization of the cis-element in the first intron of the Ars gene in the sea urchin Dev. Growth Differ. 37 1995 373 378
80. Jan Y.N. Jan L.Y. Asymmetric cell division Nature 392 1998 775 778
81. Jeffery W.R. Axis determination in sea urchin embryos: From confusion to evolution Trends Genet. 8 1992 223 225
82. Kenny A.P. Kozlowski D.J. Oleksyn D.W. Angerer L.M. Angerer R.C. SpSoxB1, a maternally encoded transcription factor asymmetrically distributed among early sea urchin blastomeres Development 126 1999 5473 5483
83. Khaner O. Wilt F. Interactions of different vegetal cells with mesomeres during early stages of sea urchin development Development 112 1991 881 890
84. Killian C.E. Wilt F.H. The accumulation and translation of a spicule matrix protein mRNA during sea urchin development Dev. Biol. 133 1989 148 156
85. Kingsley P.D. Angerer L.M. Angerer R.C. Major temporal and spatial patterns of gene expression during differentiation of the sea urchin embryo Dev. Biol. 155 1993 216 234
86. Kirchhamer C.V. Davidson E.H. Spatial and temporal information processing in the sea urchin embryo: Modular and intramodular organization of the CyIIIa gene cis-regulatory system Development 122 1996 333 348
87. Kirchhamer C.V. Yuh C.-H. Davidson E.H. Modular cis-regulatory organization of developmentally expressed genes: Two genes transcribed territorially in the sea urchin embryo, and additional examples Proc. Natl. Acad. Sci. USA 93 1996 9322 9328
88. Kissinger J.C. Raff R.A. Evolutionary changes in sites and timing of actin gene expression in embryos of the direct- and indirect-developing sea urchins, Heliocidaris erythrogramma and H. tuberculata Dev. Genes Evol. 208 1998 82 93
89. Kitajima T. Okazaki K. Spicule formation in vitro by the descendants of precocious micromeres formed at the 8-cell stage of sea urchin embryos Dev. Growth Differ. 22 1980 265 279
90. Kiyama T. Akasaka K. Takata K. Mitsunaga-Nakatsubo K. Sakamoto N. Shimada H. Structure and function of a sea urchin orthodenticle-related gene (Hpotx) Dev. Biol. 193 1998 139 145
91. Kiyomoto M. Shirai H. The determinant for archenteron formation in starfish: Co-culture of an animal egg fragment-derived cell cluster and a selected blastomere Dev. Growth Differ. 35 1993 99 105
92. Klein P.S. Melton D.A. A molecular mechanism for the effect of lithium on development Proc. Natl. Acad. Sci. USA 93 1996 8455 8459
93. Klueg K.M. Harkey M.A. Raff R.A. Mechanisms of evolutionary changes in timing, spatial expression, and mRNA processing in the msp130 gene in a direct-developing sea urchin, Heliocidaris erythrogramma Dev. Biol. 182 1997 121 133
94. Kominami T. Determination of the dorsoventral axis in early embryos of the sea urchin, Hemicentrotus pulcherrimus Dev. Biol. 127 1988 187 196
95. Kontrogianni-Konstantopoulos A. Vlahou A. Vu D. Flytzanis C.N. A novel sea urchin nuclear receptor encoded by alternatively spliced maternal RNAs Dev. Biol. 177 1996 371 382
96. Kozlowski D.J. Gagnon M.L. Marchant J.K. Reynolds S.D. Angerer L.M. Angerer R.C. Characterization of a SpAN promoter sufficient to mediate correct spatial regulation along the animal-vegetal axis of the sea urchin embryo Dev. Biol. 176 1996 95 107
97. Krufka A. Johnson R.G. Wylie C.C. Heasman J. Evidence that dorsal-ventral differences in gap junctional communication in the early Xenopus embryo are generated by β-catenin independent of cell adhesion effects Dev. Biol. 200 1998 92 102
98. Kuraishi R. Osanai K. Contribution of maternal factors and cellular interaction to determination of archenteron in the starfish embryo Development 120 1994 2619 2628
99. Kurokawa D. Kitajima T. Mitsunaga-Nakatsubo K. Amemiya S. Shimada H. Akasaka K. Hp-ets , an ets-related transcription factor implicated in primary mesenchyme cell differentiation in the sea urchin embryo Mech. Dev. 80 1999 41 52
100. Laney J.D. Hochstrasser M. Substrate targeting in the ubiquitin system Cell 97 1999 427 430
101. Langelan R.E. Whiteley A.H. Unequal cleavage and the differentiation of echinoid primary mesenchyme Dev. Biol. 109 1985 464 475
102. Larabell C.A. Torres M. Rowning B.A. Yost C. Miller J.R. Wu M. Kimelman D. Moon R.T. Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in β-catenin that are modulated by the Wnt signaling pathway J. Cell. Biol. 136 1997 1123 1136
103. Lee J.J. Calzone F.J. Britten R.J. Davidson E.H. Activation of sea urchin actin genes during embryogenesis: Measurement of transcript accumulation from five different genes in Strongylocentrotus purpuratus J. Mol. Biol. 188 1986 173 183
104. Lepage T. Ghiglione C. Gache C. Spatial and temporal expression pattern during sea urchin embryogenesis of a gene coding for a protease homologous to the human protein BMP-1 and to the product of the Drosophila dorsal-ventral patterning gene tolloid Development 114 1992 147 164
105. Lepage T. Sardet C. Gache C. Spatial expression of the hatching enzyme gene in the sea urchin embryo Dev. Biol. 150 1992 23 32
106. Leyns L. Bouwmeister T. Kin S.-H. Piccolo S. DeRobertis E.M. Frz-b is a secreted antagonist of Wnt signaling expressed in the Spemann organizer Cell 88 1997 747 756
107. Li N. Chuang C.-K. Mao C.-A. Angerer L.M. Klein W.H. Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus Dev. Biol. 187 1997 253 266
108. Livant D.L. Cutting A. Britten R.J. Davidson E.H. An in vivo titration of regulatory factors required for expression of a fusion gene in transgenic sea urchin embryos Proc. Natl. Acad. Sci. USA 85 1988 7607 7611
109. Livingston B.T. Wilt F.H. Lithium evokes expression of vegetal-specific molecules in the animal blastomeres of sea urchin embryos Proc. Natl. Acad. Sci. USA 86 1989 3669 3673
110. Livingston B.T. Wilt F.H. Range and stability of cell fate determination in isolated sea urchin blastomeres Development 108 1990 403 410
111. Logan C.Y. McClay D.R. The allocation of early blastomeres to the ectoderm and endoderm is variable in the sea urchin embryo Development 124 1997 2213 2223
112. Logan C.Y. McClay D.R. The lineages that give rise to the endoderm and mesoderm in the sea urchin embryo Moody S. Cell Fate and Lineage Determination 1998 Academic Press New York 41 58
113. Logan C.Y. Miller J.R. Ferkowicz M.J. McClay D.R. Nuclear-catenin is required to specify vegetal cell fates in the sea urchin embryo Development 126 1999 345 357
114. Luke N.H. Killian C.E. Livingston B.T. Spfkh1 encodes a transcription factor implicated in gut formation during sea urchin development Dev. Growth Differ. 39 1997 285 294
115. Malinda K.M. Ettensohn C.A. Primary mesenchyme cell migration in the sea urchin embryo: Distribution of directional cues Dev. Biol. 164 1994 562 578
116. Mao C.-A. Gan L. Klein W.H. Multiple Otx binding sites required for expression of the Strongylocentrotus purpuratus Spec2a gene Dev. Biol. 165 1994 229 242
117. Mao C.-A. Wikramanayake A.H. Gan L. Chaung C.-K. Summers R.G. Klein W.H. Altering cell fates in sea urchin embryos by overexpressing SpOtx, an orthodenticle-related protein Development 122 1996 1489 1498
118. Maruyama Y.K. Nakaseko Y. Yagi S. Localization of cytoplasmic determinants responsible for primary mesenchyme formation and gastrulation in the unfertilized egg of the sea urchin Hemicentrotus pulcherrimus J. Exp. Zool. 236 1985 155 163
119. McCain E.R. McClay D.R. The establishment of bilateral asymmetry in sea urchin embryos Development 120 1994 395 404
120. McClay D.R. Logan C.Y. Regulative capacity of the archenteron during gastrulation in the sea urchin Development 122 1996 607 616
121. Miller J.R. McClay D.R. Changes in the pattern of adherens junction-associated β-catenin accompany morphogenesis in the sea urchin embryo Dev. Biol. 192 1997 310 322
122. Miller J.R. Moon R.T. Signal transduction through β-catenin and specification of cell fate during embryogenesis Genes Dev. 10 1996 2527 2539
123. Miller R.N. Dalamagas D.G. Kingsley P.D. Ettensohn C.A. Expression of S9 and actin CyIIa mRNAs reveals dorso-ventral polarity and mesodermal sublineages in the vegetal plate of the sea urchin embryo Mech. Dev. 60 1996 3 12
124. Minokawa T. Amemiya S. Timing of the potential of micromere-descendants in echinoid embryos to induce endoderm differentiation of mesomere descendants Develop. Growth Differ. 41 1999 535 547
125. Minokawa T. Hamaguchi Y. Amemiya S. Skeletogenic potential of induced secondary mesenchyme cells derived from the presumptive ectoderm in echinoid embryos Dev. Genes Evol. 206 1997 472 476
126. Molenaar M. van de Wetering M. Oosterwegel M. Peterson-Maduro J. Godsave S. Korinek V. Roose J. Destree O. Clevers H. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos Cell 86 1996 391 399
127. Montana G. Romancino D.P. diCarlo M.D. Cloning, expression, and localization of a new member of a Paracentrotus lividus cell surface multigene family Mol. Reprod. Dev. 44 1996 36 43
128. Moon R.T. Brown J.D. Torres M. WNTs modulate cell fate and behavior during vertebrate development Trends Genet. 13 1997 157 162
129. Morisato D. Anderson K.V. Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo Annu. Rev. Genet. 29 1895 371 399
130. Morris V.B. Apluteal development of the sea urchin Holopneustes purpurescens Agassiz (Echinodermata: Echinoidea: Euechinoidea) Zool. J. Linn. Soc. 114 1995 349 364
131. Niemeyer C.C. Flytzanis C.N. Upstream elements involved in the embryonic regulation of the sea urchin CyIIIb actin gene: Temporal and spatial specific interactions at a single cis-acting element Dev. Biol. 156 1993 293 302
132. Okazaki K. Spicule formation by isolated micromeres of the sea urchin embryo Am. Zool. 15 1975 567 581
133. Okazaki K. Fukushi T. Dan D. Cyto-embryological studies of sea urchins. IV. Correlation between the shape of the ectodermal cells and the arrangement of the primary mesenchyme cells in sea urchin larvae Acta Embryol. Morphol. Exp. 5 1962 17 31
134. Olson D.J. Christian J.L. Moon R.T. Effect of Wnt-1 and related proteins on gap junctional communication in Xenopus embryos Science 252 1991 1173 1176
135. Orford K. Crockett C. Jensen J.P. Weissman A.M. Byers S.W. Serine phosphorylation-regulated ubiquitination and degradation of β-catenin J. Biol. Chem. 272 1997 24735 24738
136. Pehrson J.R. Cohen L.H. The fate of the small micromeres in sea urchin development Dev. Biol. 113 1986 522 526
137. Qi H. Rand M.D. Wu X. Sestan N. Wang W. Rakic P. Xu T. Artavanis-Tsakonas S. Processing of the Notch ligand Delta by the metalloprotease Kuzbanian Science 283 1999 91 94
138. Raff E.C. Popodi E.M. Sly B.J. Turner F.R. Villinski J.T. Raff R.A. A novel ontogenetic pathway in hybrid embryos between species with different modes of development Development 126 1999 1937 1945
139. Raff R.A. Direct-developing sea urchins and the evolutionary reorganization of early development Bioessays 14 1992 211 218
140. Ransick A. Davidson E.H. A complete second gut induced by transplanted micromeres in the sea urchin embryo Science 259 1993 1134 1138
141. Ransick A. Davidson E.H. Micromeres are required for normal vegetal plate specification in sea urchin embryos Development 121 1995 3215 3222
142. Ransick A. Davidson E.H. Late specification of veg1 lineages to endodermal fate in the sea urchin embryo Dev. Biol. 195 1998 38 48
143. Ransick A. Ernst S. Britten R.J. Davidson E.H. Whole mount in situ hybridization shows Endo 16 to be a marker for the vegetal plate territory in sea urchin embryos Mech. Dev. 42 1993 117 124
144. Reynolds S.D. Angerer L.M. Palis J. Nasir A. Angerer R.C. Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1 Development 114 1992 769 786
145. Roberson M. Neri A. Oppenheimer S.B. Distribution of concanavalin A receptor sites on specific populations of embryonic cells Science 189 1975 639 640
146. Roose J. Molenaar M. Peterson J. Hurnkamp J. Brantjes H. Moerer P. van de Wetering M. Destree O. Clevers H. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors Nature 8 1998 608 612
147. Ruffins S.W. Ettensohn C.A. A fate map of the vegetal plate of the sea urchin ( Lytechinus variegatus ) mesenchyme blastula Development 122 1996 253 263
148. Ruiz i Altaba A. Jessell T.M. Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis Development 116 1992 81 93
149. Sakamoto N. Akasaka K. Nitsunaga-Nakatsubo K. Takata K. Nishitani T. Shimada H. Two isoforms of orthodenticle-related proteins (Hpotx) bind to the enhancer element of sea urchin arylsulfatase gene Dev. Biol. 181 1997 284 295
150. Schatten G. Sperm incorporation, the pronuclear migrations, and their relation to the establishment of the first embryonic axis: Time lapse video microscopy of the movements during fertilization of the sea urchin Lytechinus variegatus Dev. Biol. 86 1981 426 437
151. Schnabel R. Priess J.R. C. elegans II 1997 CSHL Press New York 361 382
152. Schroeder T.E. Expression of the prefertilization polar axis in sea urchin eggs Dev. Biol. 79 1980 428 443
153. Schroeder T.E. The jelly canal: Marker of polarity for sea urchin oocytes, eggs, and embryos Exp. Cell Res. 128 1980 490 494
154. Schroeder T.E. Development of a “primitive” sea urchin ( Eucidaris tribuloides ): Irregularities in the hyaline layer, micromeres, and primary mesenchyme Biol. Bull. 161 1981 141 151
155. Seeling J.M. Miller J.R. Gil R. Moon R.T. White R. Virshup D.M. Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A Science 283 1999 2089 2091
156. Senger D.R. Gross P.R. Macromolecule synthesis and determination in sea urchin blastomeres at the sixteen-cell stage Dev. Biol. 65 1978 404 415
157. Sherrocks A.D. Brown A.L. Ling Y. Yates P.R. The ETS-domain transcription factor family Int. J. Biochem. Cell Biol. 29 1997 1371 1387
158. Sherwood D.R. McClay D.R. Identification and localization of a sea urchin Notch homologue: Insights into vegetal plate regionalization and Notch receptor regulation Development 124 1997 3363 3374
159. Sherwood D.R. McClay D.R. LvNotch signaling mediates secondary mesenchyme specification in the sea urchin embryo Development 126 1999 1703 1713
160. Slack J.M. From Egg to Embryo: Regional Specification in Early Development 1991 Cambridge Univ. Press Cambridge
161. Smith J.C. Price B.M. Green J.B.A. Weigel D. Merrmann B.G. Expression of a Xenopus homolog of Brachyury (T) is an immediate—early response to mesoderm induction Cell 67 1991 79 87
162. Sokol S.Y. Analysis of dishevelled signalling pathways during Xenopus development Curr. Biol. 6 1996 1456 1467
163. Stambolic V. Ruel L. Woodgett J.R. Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells Curr. Biol. 6 1996 1664 1668
164. Summers R. Morrill J. Leith A. Marko M. Piston D. Stonebrakes A. A stereometric analysis of karyokinesis, cytokinesis and cell arrangements during and following fourth cleavage period in the sea urchin, Lytechinus variegatus Dev. Growth Diff. 35 1903 41 57
165. Summers R.G. Piston D.W. Harris K.M. Morrill J.B. The orientation of first cleavage in the sea urchin embryo, Lytechinus variegatus , does not specify the axes of bilateral symmetry Dev. Biol. 175 1996 177 183
166. Sweet H. Hodor P.G. Ettensohn C.A. The role of micromere signaling in Notch activation and mesoderm specification during sea urchin embryogenesis Development 126 1999 5255 5265
167. Tanaka Y. Effects of surfactants on the cleavage and further development of sea urchin embryos. 1. The inhibition of micromere formation at the fourth cleavage Dev. Growth and Differ. 18 1976 113 122
168. Tanaka Y. Distribution and redistribution of pigment granules in the development of sea urchin embryos Wilh. Roux Arch. 190 1981 267 273
169. Thézé N. Calzone F.J. Thiebaud P. Hill R.L. Britten R.J. Davidson E.H. Sequences of the CyIIIa actin gene regulatory domain bound specifically by sea urchin embryo nuclear proteins Mol. Reprod. Dev. 25 1990 110 122
170. van Weeren P.C. de Bruyn K.M. de Vries-Smits A.M. van Lint J. Burgering B.M. Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation J. Biol. Chem. 273 1998 13150 13156
171. Vlahou A. Gonzalez-Rimbau M. Flytzanis C.N. Maternal mRNA encoding the orphan steroid receptor SpCOUP is localized in sea urchin eggs Development 122 1996 521 526
172. Vonica A. Weng W. Gumbiner B.M. Venuti J.M. TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis Dev. Biol. 217 2000 230 243
173. Waltzer L. Bienz M. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling Nature 395 1998 521 525
174. Wang D.G.-W. Kirchhamer C.V. Britten F.J. Davidson E.H. SpZ12-1, a negative regulator required for spatial control of the territory-specific CyIIIa gene in the sea urchin embryo Development 121 1995 1111 1122
175. Wang S. Krinks M. Lin K. Luyten F.P. Moos M. Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits wnt-8 Cell 88 1997 757 766
176. Wang W. Wikramanayake A.H. Gonzalez-Rimbau M. Vlahou A. Flytzanis C.N. Klein W.H. Very early and transient vegetal plate expression of SpKrox1 , a Krüppel/Krox gene from Strongylocentrotus purpuratus Mech. Dev. 60 1996 185 195
177. Wardle F. Angerer L.M. Angerer R.C. Dale L. Regulation of BMP signaling by the MP1/TLD-related metalloprotease, SpAN Dev. Biol. 206 1999 63 72
178. Wasylyk B. Hagman J. Gutierrez-Hartmann A. Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway Trends Biochem. Sci. 23 1998 213 216
179. Wei Z. Angerer L.M. Angerer R.C. Multiple positive cis-elements regulate the asymmetric expression of the SpHE gene along the sea urchin embryo animal-vegetal axis Dev. Biol. 187 1997 71 78
180. Wei Z. Angerer L.M. Angerer R.C. Spatially regulated SpEts4 transcription factor activity along the sea urchin embryo animal-vegetal axis Development 126 1999 1729 1737
181. Wei Z. Angerer R.C. Angerer L.M. Identification of a new sea urchin Ets protein, SpEts4, by yeast one-hybrid screening with the hatching enzyme promoter Mol. Cell. Biol. 19 1999 1271 1278
182. Wei Z. Angerer L.M. Gagnon M.L. Angerer R.C. Characterization of the SpHE promoter that is spatially regulated along the animal-vegetal axis of the sea urchin embryo Dev. Biol. 171 1995 195 211
183. Wei Z. Kenny A.P. Angerer L.M. Angerer R.C. The SpHE gene is downregulated in sea urchin late blastulae despite persistance of multiple positive factors sufficient to activate its promoter Mech. Dev. 67 1997 171 178
184. Wessel G.M. Goldberg L. Lennarz W.J. Klein W.H. Gastrulation in the sea urchin is accompanied by the accumulation of an endoderm-specific mRNA Dev. Biol. 136 1989 526 536
185. Wessel G.M. McClay D.R. Sequential expression of germ layer specific molecules in the sea urchin embryo Dev. Biol. 111 1985 451 463
186. Wikramanayake A.H. Brandhorst B.P. Klein W.H. Autonomous and non-autonomous differentiation of ectoderm in different sea urchin species Development 121 1995 1497 1505
187. Wikramanayake A.H. Huang L. Dayal S. Klein W.H. Wnt signaling is required for gastrulation and aboral ectoderm formation in the sea urchin embryo Dev. Biol. 198 1998 182 [Abstract]
188. Wikramanayake A.H. Huang L. Klein W.H. β-catenin is essential for patterning the maternally specified animal-vegetal axis in the sea urchin embryo Proc. Natl. Acad. Sci. USA 95 1998 9343 9348
189. Wikramanayake A.H. Klein W.H. Multiple signaling events specify ectoderm and pattern the oral-aboral axis in the sea urchin embryo Development 124 1997 13 20
190. Wray G.A. McClay D.R. Molecular heterochronies and heterotopies in early echinoid development Evolution 43 1989 803 813
191. Wray G.A. Raff R.A. Novel origins of lineage founder cells in the direct-developing sea urchin Heliocidaris erythrogramma Dev. Biol. 141 1990 41 54
192. Xu N. Niemeyer C.C. Gonzalez-Rimbau M. Bogosian E.A. Flytzanis C.N. Distal cis-acting elements restrict expression of the CyIIIb actin gene in the aboral ectoderm of the sea urchin embryo Mech. Dev. 60 1996 151 162
193. Yang Q. Angerer L.M. Angerer R.C. Structure and tissue-specific developmental expression of a sea urchin arylsulfatase gene Dev. Biol. 135 1989 53 65
194. Yoshikawa S. Oral/aboral ectoderm differentiation of the sea urchin embryo depends on a planar or secretory signal from the vegetal hemisphere Dev. Growth Differ. 39 1997 319 327
195. Yost C. Farr G.H. III Pierce S.B. Ferkey D.M. Chen M.M. Kimelman D. GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis Cell 93 1998 1031 1041
196. Zeller R.W. Griffith J.D. Moore J.G. Kirchhamer C.V. Britten R.J. Davidson E.H. A multimerizing transcription factor of sea urchin embryos capable of looping DNA Proc. Natl. Acad. Sci. USA 92 1995 2989 2993
197. Zeng L. Fagotto F. Zhang T. Hsu W. Vasicek T.J. Perry W.L. III Lee J.J. Tilghman S.M. Gumbiner B.M. Costantini F. The mouse fused locus encodes axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation Cell 90 1997 181 192
198. Zhang J. Houston D.W. King M.L. Payne C. Wylie C. Heasman J. The role of maternal VegT in establishing the primary germ layers in Xenopus embryos Cell 94 1998 515 524