SpMyb functions as an intramodular repressor to regulate spatial expression of CyIIIa in sea urchin embryos

Development

Volumn 124, Issue 23, 1997, Pages 4717-4727

  Coffman, James A ^a   Kirchhamer, Carmen V ^a,b   Harrington, Michael G ^a   Davidson, Eric H ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

CyIIIa; Embryogenesis; Myb; Strongylocentrotus purpuratus; Transcriptional regulation

Indexed keywords

ACTIN; ANTIBODY; COMPLEMENTARY DNA; DNA; ONCOPROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; EMBRYO; GENE; GENE REPRESSION; GENE TRANSFER; IMMUNOPRECIPITATION; MOLECULAR CLONING; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE C MYB; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PURIFICATION; REPORTER GENE; SEA URCHIN; STRUCTURE ACTIVITY RELATION;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CHROMATOGRAPHY, AFFINITY; DNA-BINDING PROTEINS; EMBRYO, NONMAMMALIAN; GENE DOSAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; REPRESSOR PROTEINS; SEA URCHINS; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS;

ANIMALIA; ECHINOIDEA; INVERTEBRATA; STRONGYLOCENTROTUS PURPURATUS;

EID: 0031468319     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Arnone, M. I. and Davidson, E. H. (1997). The hardwiring of development: organization and function of genomic regulatory systems. Development 124, 1851-1864.
2. Aziz, N., Miglarese, M. R., Hendrickson, R. C., Shabanowitz, J., Sturgill, T. W., Hunt, D. F. and Bender, T. P. (1995). Modulation of c-Myb-induced transcription activation by a phosphorylation site near the negative regulatory domain. Proc. Natl. Acad. Sci. USA 92, 6429-6433.
3. Boyle, W. J., Lipsick, J. S. and Baluda, M. A. (1986). Antibodies to the evolutionary conserved amino-terminal region of the v-myb-cncoded protein detect the c-myb protein in widely divergent metazoan species. Proc. Natl. Acad. Sci. USA 83.4685-4689.
4. Britten, R. J., Cetta, A. and Davidson, E. H. (1978) The single-copy DNA sequence polymorphism of the sea urchin Strongylocentrotus purpuratus. Cell 15, 175-1186.
5. Calzone, F. J., Thézé, N., Thiebaud, P., Hill, R. L., Britten, R. J. and Davidson, E. H. (1988). Developmental appearance of factors that bind specifically to cis-regulatory sequences of a gene expressed in the sea urchin embryo. Genes Dev. 2, 1074-1088.
6. Calzone, F. J., Höög, C., Teplow, D. B., Cutting, A. F., Zeller, R. W., Britten, R. J. and Davidson, E. H. (1991). Gene regulatory factors of the sea urchin embryo. I. Purification by affinity chromatography and cloning of P3A2, a novel DNA binding protein. Development 112, 335-350.
7. Char, B. R., Bell, J. R., Dovola, J., Coffman, J. A., Harrington, M. G., Becerra, J. C., Davidson, E. H., Calzone, F. J. and Maxson, R. (1993) SpOct, a gene encoding the major octamer-binding protein in sea urchin embryos. Expression profile, evolutionary relationships, and DNA binding of the expressed protein. Dev. Biol. 158, 350-363.
8. Chen, Z.-Q., Kan, N. C., Pribyl, L., Kautenberger, J. A., Moudrianakis, E. and Papas, T. S. (1988). Molecular cloning of the Ets proto-oncogene of the sea urchin and analysis of its developmental expression. Dev: Biol. 125, 432-440.
9. Coffman, J. A., Moore, J. G., Calzone, F. J., Britten, R. J., Hood, L. E. and Davidson, E. H. (1992). Automated sequential affinity chromatography of sea urchin embryo DNA binding proteins. Mal. Mar. Biol. Biotech 1, 136-146.
10. Coffman, J. A., Kirchhamer, C. V., Harrington, M. G. and Davidson, E. H. (1996). SpRunt-1, a new member of the runt-domain family of transcription factors, is a positive regulator of the aboral ectoderm-specific CyIIIa gene in sea urchin embryos. Dev. Biol. 174, 43-54.
11. Dubendorff, J. W., Whittaker, L. J., Eltman, J. T. and Lipsick, J. S. (1992) Carboxy-terminal elements of c-Myb negatively regulate transcriptional activation in cis and in trans. Genes Dev. 6, 2524-2535.
12. Dudek, H., Tantravahi, R. V., Rao, V. N., Reddy, E. S. and Reddy, E. P. (1992). Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoter. Proc. Natl. Acad. Sci. USA 89, 1291-1295.
13. Franks, R. R., Anderson, R., Moore, J. G., Hough-Evans, B. R., Britten, R. J. and Davidson, E. H. (1990). Competitive titration in living sea urchin embryos of regulatory factors required for expression of the CyIIIa actin gene. Development 110, 31 -40.
14. Foos, G., Grimm, S. and Klempnauer, K.-H. (1992). Functional antagonism between members of the myb family: B-myb inhibits v-myb-induced gene activation. EMBO J. 11, 4619-4629.
15. Golay, J., Loffarelli, L., Luppi, M., Castellano, M. and Introna, M. (1994) The human A-myb protein is a strong activator of transcription. Oncogene 9, 2469-2479.
16. Graf, T. (1992). Myb: A transcriptional activator linking proliferation and differentiation in hematopoietic cells. Curr. Opinion Genet. Dev. 2, 249-255.
17. Gray, S. and Levine, M. (1996). Transcriptional repression in development. Curr. Opin. Cell Biol. 8, 358-364.
18. Hernandez-Munain, C. and Krangel, M. S. (1994). Regulation of the T-cell receptor δ enhancer by functional cooperation between c-Myb and core-binding factors. Mol. Cell. Biol. 14, 473-483.
19. Hernandez-Munain, C. and Krangel, M. S. (1995). c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor 5 enhancer. Mol. Cell. Biol. 15, 3090-3099.
20. Higgins, D. G., Bleasby, A J. and Fuchs, R. (1992). Clustal V: Improved software for multiple sequence alignment. Computer Applications in the Biosciences (CABIOS) 8, 189-191.
21. Hough-Evans, B. R., Franks, R. R., Zeller, R. W., Britten, R. J. and Davidson, E. H. (1990). Negative spatial regulation of the lineage-specific CyIIIa actin gene in the sea urchin embryo Development 110, 41 -50.
22. Hsiang, H. H., Goldman. J. P. and Raulet, D. H. (1995). The role of c-Myb or a related factor in regulating the T-cell receptor γ gene enhancer. J. Immunol. 154, 5195-5204.
23. Kirchhamer, C. V. and Davidson, E. H. (1996). Spatial and temporal information processing in the sea urchin embryo: Modular and intramodular organization of the CyIIIa gene cis-regulatory system. Development 122, 333-348.
24. Kirchhamer, C. V., Yuh, C. -H. and Davidson, E. H. (1996). Modular cis-regulatory organization of developmentally expressed genes: Two genes transcribed territorially in the sea urchin embryo, and additional examples. Proc. Natl. Acad. Sci. USA 93, 9.322-9328.
25. Lipsick, J. S. (1996). One billion years of Myb. Oncogene 13, 223-235.
26. Luscher, B. and Eisenman, R. N. (1990) New light on Myc and Myb. Part II. Myb. Genes Dev. 4, 2235-2241.
27. McMahon, A. P., Flytzanis, C. N., Hough-Evans, B. R., Katula, K. S., Britten, R. J. and Davidson, E. H. (1985). Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Dev. Biol. 108, 420-430.
28. Miglarese, M. R., Richardson, A. F., Aziz, N. and Bender, T. P. (1996). Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain. J. Biol. Chem. 271, 22697-22705.
29. Ransick, R., Ernst, S. G., Britten, R. J. and Davidson, E. H. (1993). Whole mount in situ hybridization shows Endo 16 to be a marker for the vegetal plate territory in sea urchin embryos. Mech. Dev. 42, 117-124.
30. Reddy, M. A., Yang, B. -S., Yue, X., Barnett, C. J. K., Ross, I. L., Sweet, M. J., Hume, D. A. and Ostrowski, M. C. (1994). Opposing actions of c-ets/PU. 1 and c-myb protooncogene products in regulating the macrophage - specific promotors of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J. Exp. Med. 180, 2309-2319.
31. Stober-Grässer, U., Brydolf, B., Bin, X., Crasser, F., Firtel, R. A. and Lipsick, J. S. (1992). The Myb DNA-bindmg domain is highly conserved in Dictyostelium discoideum. Oncogene 7, 589-596.
32. Takahashi, T., Nakagoshi, H., Sarai, A., Nomura, N., Yamamoto, T. and Ishii, S. (1995). Human A-myb gene encodes a transcriptional activator containing the negative regulatory domains. FEBS letters 358, 89-96.
33. Tashiro, S., Takemoto, Y., Handa, H. and Ishii, S. (1995). Cell type-spccific trans-activation by the B-myb gene product: requirement of the putative cofactor binding to the C-terminal conserved domain. Oncogene 10, 1699-1707.
34. Thézé, N., Calzone, F. J., Thiebaud, P., Hill, R. L., Britten, R. J. and Davidson, E. H. (1990). Sequences of the CyIIIa actin gene regulatory domain bound specifically by sea urchin embryo nuclear proteins. Mol. Reprod. Dev. 25, 110-122.
35. Vandenbark, G. R., Chen, Y., Friday, E., Pavlik, K., Anthony, B., deCastro, C. and Kaufman, R. E. (1996). Complex regulation of human c-kit transcription by promoter repressors. activators, and specific myb elements. Cell Growth Differ. 7, 1383-1392.
36. Wang, D. G. -W., Kirchhamer, C. V., Britten, R. J. and Davidson, E. H. (1995). SpZ12-1, a negative regulator required for spatial control of the territory-specific CyIIIa gene in the sea urchin embryo. Development 121, 1111-1122.
37. Wotton, D., Ghysdael, J., Wang, S., Speck, N. A. and Owen, M. J. (1994). Cooperative binding of Ets-1 and core binding factor to DNA. Mol. Cell Biol. 14, 840-850.
38. Zaiman, A. L. and Lenz, J. (1996). Transcriptional activation of a retrovirus enchancer by CBF (AML1) requires a second factor. Evidence for cooperatively with c-Myb. J. Virol. 70, 5618-5629.
39. Zeller, R. W., Coffman, J. A., Harrington, M. G., Britten, R. J. and Davidson, E. H. (1995a). SpGCF1, a sea urchin embryo DNA binding protein, exists as five nested variants encoded by a single mRNA. Dev. Biol. 169, 713-727.
40. Zeller, R. W., Griffith, J. D., Moore, J. G., Kirchhamer, C. V., Britten, R. J. and Davidson, E. H. (1995b). A multimerizing transcription factor of sea urchin embryos capable of looping DNA. Proc. Natl. Acad. Sci. USA 92, 2989-2993.