The Saccharomyces cerevisiae Msh2 mismatch repair protein localizes to recombination intermediates in vivo

Molecular Cell

Volumn 5, Issue 5, 2000, Pages 789-799

  Evans, Elizabeth ^a   Sugawara, Neal ^b   Haber, James E ^b   Alani, Eric ^a  

^a Department of Obstetrics Gynecology   (United States)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA MISMATCH REPAIR PROTEIN; FUNGAL DNA; FUNGAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0033636242     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80319-6     Document Type: Article

References (63)

1. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6
2. The Saccharomyces cerevisiae Msh2p and Msh6p form a complex that specifically binds to duplex oligonucleotides containing mismatched DNA base pairs
3. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae
4. Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA
5. MutS mediates heteroduplex loop formation by a translocation mechanism
6. Components and dynamics of DNA replication complexes in S. cerevisiae: Redistribution of MCM proteins and Cdc45p during S phase
7. Mismatch repair, G(2)/M cell cycle arrest and lethality after DNA damage
8. Physical interaction between components of DNA mismatch repair and nucleotide excision repair
9. Synapsis and the formation of paranemic joints by E. coli RecA protein
10. The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae
11. Nucleotide-promoted release of hMutSα from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism
12. Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
13. The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss
14. The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast
15. Removal of one nonhomologous DNA end during gene conversion by a RAD1- and MSH2-independent pathway
16. Mismatch repair systems in Saccharomyces cerevisiae
17. Crossovers between diverged sequences are regulated by mismatch repair proteins in yeast
18. Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast
19. Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation
20. hMutsα and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
21. Application of high efficiency lithium acetate transformation of intact yeast cells using single-stranded nucleic acids as carrier
22. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
23. The many interfaces of Mre11
24. Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3
25. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
26. The mismatch repair system contributes to meiotic sterility in an interspecific yeast hybrid
27. Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae
28. Directionality and regulation of cassette substitution in yeast
29. Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins
30. Eukaryotic DNA mismatch repair
31. Saccharomyces Ku70, mre11/rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage
32. Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes
33. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
34. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
35. Budding yeast centromere composition and assembly as revealed by in vivo cross-linking
36. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
37. Mismatch repair in replication fidelity, genetic recombination, and cancer biology
38. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
39. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
40. In situ visualization of DNA double-strand break repair in human fibroblasts
41. Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes
42. Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae
43. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisae
44. Mismatch repair and the fidelity of genetic recombination
45. Heteroduplex formation and mismatch repair of the 'stuck' mutation during mating-type switching in Saccharomyces cerevisiae
46. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants
47. The formation of paranemic and plectonemic joints between DNA molecules by the recA and single-stranded DNA-binding proteins of Escherichia coli
48. The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization
49. Isolation and characterization of yeast DNA repair genes. I. The cloning of the RAD52 gene
50. Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae
51. Effect of base pair mismatches on recombination via the RecBCD pathway
52. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
53. Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair
54. Separation of function mutations in S. cerevisiae MSH2 that confer mismatch repair defects but do not affect nonhomologous tail removal during recombination
55. Characterization of double-strand break-induced recombination: Homology requirements and single-stranded DNA formation
56. Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break repair-induced recombination
57. The double-strand-break repair model for recombination
58. A novel mre11 mutation impairs processing of double-strand breaks of DNA during both mitosis and meiosis
59. Chromosome pairing via multiple interstitial interactions before and during meiosis in yeast
60. Intermediates of recombination during mating type switching in Saccharomyces cerevisiae
61. Dissociation of mismatch recognition and ATPase activity by hMSH2-hMSH3
62. Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs
63. Apoptosis induced by overexpression of hMSH2 or hMLH1