Conformational restriction of the Tyr53 side-chain in the decapeptide HEL[52-61]: Effects on binding to MHC-II I-A(k) molecule and TCR recognition

Journal of Peptide Research

Volumn 56, Issue 6, 2000, Pages 398-408

  Casimir, J R ^a,b,c   Iterbeke, K ^b   Van Den Nest, W ^b   Tourwe D ^b   Trescol Biemont M C ^d   Rabourdin Combe, C ^d   Dumortier, H ^c   Muller, S ^c   Gerlier, D ^a   Paris, J ^a,c  

^a UNIVERSITÉ LYON 1   (France)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d INSERM   (France)

Author keywords

4 amino 1,2,4,5 tetrahydro 8 hydroxy 2 benzazepine 3 one; Conformational restriction; Constrained amino acids; Hen egg lysozyme; MHC II I A(k); T cell recognition

Indexed keywords

1,2,3,4 TETRAHYDRO 7 HYDROXYISOQUINOLINE 3 CARBOXYLIC ACID; 1,2,3,4 TETRAHYDROISOQUINOLINE 3 CARBOXYLIC ACID; 2 AMINO 5 HYDROXYINDAN 2 CARBOXYLIC ACID; 2 AMINO 6 HYDROXYTETRALIN 2 CARBOXYLIC ACID; 4 AMINO 1,2,4,5 TETRAHYDRO 2 BENZAZEPIN 3 ONE; 4 AMINO 1,2,4,5 TETRAHYDRO 8 HYDROXY 2 BENZAZEPIN 3 ONE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PHENYLALANINE DERIVATIVE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; LYSOZYME; PEPTIDE; PHENYLALANINE; TYROSINE;

ARTICLE; CYCLIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOLECULAR RECOGNITION; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; RESIDUE ANALYSIS; STRUCTURE ANALYSIS; SYNTHESIS; T LYMPHOCYTE RECEPTOR GENE; AMINO ACID SEQUENCE; ANIMAL; ANTIGEN PRESENTING CELL; B LYMPHOCYTE; CHEMICAL MODEL; CHEMISTRY; CHICKEN; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR GENETICS; MOUSE; PEPTIDE SYNTHESIS; PROTEIN BINDING; TEMPERATURE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN-PRESENTING CELLS; B-LYMPHOCYTES; CHICKENS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MURAMIDASE; PEPTIDE BIOSYNTHESIS; PEPTIDES; PHENYLALANINE; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ANTIGEN, T-CELL; TEMPERATURE; TYROSINE;

EID: 0033635126     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2000.00777.x     Document Type: Article

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