Somatic gene tranfer: Implications for cardiovascular control

Experimental Physiology

Volumn 85, Issue 6, 2000, Pages 747-755

  Kasparov, S ^a   Paton, J F R ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; BETA GALACTOSIDASE; CYCLOSPORIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MANNITOL; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN ANTIBODY; VIRUS DNA; VIRUS RNA; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN FUNCTION; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR SYSTEM; CELL FUNCTION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INHIBITION; GENE TARGETING; GENE TRANSFER; GENETIC MANIPULATION; IN VIVO STUDY; MEDICAL RESEARCH; METHODOLOGY; MOLECULAR BIOLOGY; NERVE CELL; NONHUMAN; PHYSIOLOGY; RAT; REVIEW; SOLITARY TRACT NUCLEUS; SOMATIC CELL GENETICS; VIRUS REPLICATION; ANIMAL; GENE VECTOR; GENETICS;

ADENOVIRIDAE; ANIMALS; CARDIOVASCULAR PHYSIOLOGY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; SOLITARY NUCLEUS;

EID: 0033625966     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-445X.2000.02144.x     Document Type: Review

References (44)

1. Temporal profile of adenovirus-mediated E. Coli lacZ gene expression in normal and postischemic gerbil hippocampus and ventricle
2. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos
3. Herpesvirus-mediated gene delivery into the rat brain: Specificity and efficiency of the neuron-specific enolase promoter
4. Adenovirus in the brain: Recent advances of gene therapy for neurodegenerative diseases
5. Selective and rapid uptake of adeno-associated virus type 2 in brain
6. Nitric oxide systems in the medulla oblongata and their involvement in autonomic control
7. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
8. Anatomy of the lower brainstem
9. Adenovirus-mediated transgene expression in nonhuman primate brain
10. Adenoviral nerve growth factor and beta-galactosidase transfer to spinal cord: A behavioral and histological analysis
11. Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarius
12. Recombinant adeno-associated virus vector: Use for transgene expression and anterograde tract tracing in the CNS
13. Gene therapy with recombinant adenovirus vectors: Evaluation of the host immune response
14. Cardiovascular responses to microinjections of glutamate into the nucleus tractus solitarili of unanesthetized supracollicular decerebrate rats
15. Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovirus: Suppression of the immune response with cyclosporin
16. Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system
17. Rapid gene transfer into cultured hippocampal neurons and acute hippocampal slices using adenoviral vectors
18. Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system
19. Tetracycline-regulated transgene expression in hippocampal neurones following transfection with adenoviral vectors
20. A neural cell-type-specific expression system using recombinant adenovirus vectors
21. Adenoviral vector mediated gene expression in the nervous system of immunocompetent Wistar and T cell-deficient nude rats: Preferential survival of transduced astroglial cells in nude rats
22. Immune responses to adenoviral vectors during gene transfer in the brain
23. Transduction of hippocampal CA1 by adenovirus in vivo
24. A role for endothelial NO synthase in LTP revealed by adenovirus mediated inhibition and rescue
25. Angiotensin II receptors within the nucleus of the solitary tract mediate the developmental attenuation of the baroreceptor vagal reflex in preweaned rats
26. Oligomerization of endothelial nitric oxide synthase. Evidence for a dominant negative effect of truncation mutants
27. Central autonomic pathways
28. Participation of AT1 and AT2 receptor subtypes in the tonic inhibitory modulation of baroreceptor reflex response by endogenous angiotensins at the nucleus tractus solitarii in the rat
29. Adenovirus-mediated gene transfer to cultured nodose sensory neurons
30. Synaptic mechanisms regulating cardiovascular afferent inputs to solitary tract nucleus
31. Effect of an anti-hypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats
32. Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus mediated gene transfer
33. Working mouse heart-brainstem preparation for studying cardiorespiratory regulation in an in-vitro milieu
34. The Sharpey-Schafer prize lecture. Nucleus tractus solitarii: Integrating structures
35. Differential effects of angiotensin II on cardiovascular reflexes mediated by nucleus tractus solitarii-I. A microinjection study
36. Sensory channel specific modulation in the nucleus of the solitary tract
37. Nitric oxide (NO) mediates baroreflex depression induced by Angiotensin II (AngII) in the solitary tract nucleus (NTS) of rat
38. A role for endothelial nitric oxide synthase (eNOS) in the nucleus of the solitary tract (NTS) in modulating baroreceptor reflex function
39. Adeno-associated virus vectors: Activity and applications in the CNS
40. Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen
41. Central nervous mechanisms contributing to cardiovascular control
42. Replication-deficient adenovirus vector transfer of gfp reporter gene into supraoptic nucleus and subfornical organ neurons
43. Gene transfer strategies for the physiologist
44. Recent advances in technology for measuring and manipulating cell signals