Synthesis and 5-HT3 receptor affinity of new quinolinecarboxylic acid derivatives

Drug Design and Discovery

Volumn 16, Issue 4, 2000, Pages 271-279

  Orjales, Aurelio ^a   Alonso Cires, Luisa ^a   López Tudanca, Pedro L ^a   Tapia, Inés ^a   Labeaga, Luis ^a   Mosquera, Ramon ^a  

^a FAES   (Spain)

Author keywords

5 HT3 affinity; 5 HT3 antagonism; Acyl; Quinolinecarboxamide; Quinolinecarboxylate

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; DOPAMINE 2 RECEPTOR; NITROGEN; QUINOLINE DERIVATIVE; QUINUCLIDINE; SEROTONIN 3 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; QUINOLINE 4 CARBOXYLIC ACID; QUINOLINE-4-CARBOXYLIC ACID; SEROTONIN 4 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; DRUG ANTAGONISM; DRUG INHIBITION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ELECTRON; LIGAND BINDING; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; STRUCTURE ANALYSIS; ANIMAL; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; GUINEA PIG; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; WISTAR RAT;

ANIMALS; DOPAMINE ANTAGONISTS; DRUG DESIGN; GUINEA PIGS; MALE; QUINOLINES; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033625295     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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