Comparative receptor mapping of serotoninergic 5-HT3 and 5-HT4 binding sites

Journal of Computer-Aided Molecular Design

Volumn 11, Issue 6, 1997, Pages 589-599

  López Rodríguez, María L ^a   Morcillo, María José ^b   Benhamú, Bellinda ^a   Rosado, María Luisa ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD NACIONAL DE EDUCACIÓN A DISTANCIA   (Spain)

Author keywords

Drug design; Molecular modeling; Pharmacophore; Selectivity

Indexed keywords

BINDING SITES; COMPUTER AIDED ANALYSIS; CONFORMATIONS; MAPPING; NITROGEN; VAN DER WAALS FORCES;

BASIC NITROGEN; BINDING-SITES; CLINICAL USE; DRUG DESIGN; EXCLUDED VOLUME; PHARMACOPHORES; RECEPTOR BINDING SITE; RECEPTOR MAPPING; SELECTIVE LIGANDS; SELECTIVITY;

LIGANDS;

LIGAND; SEROTONIN 3 RECEPTOR; SEROTONIN 4 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ARTICLE; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; METABOLISM; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

BINDING, COMPETITIVE; COMPUTER SIMULATION; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN CONFORMATION; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0031263918     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007908707650     Document Type: Review

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