Mobilisation of intracellular Ca2+ by mGluR5 metabotropic glutamate receptor activation in neonatal rat cultured dorsal root ganglia neurones

Neuropharmacology

Volumn 39, Issue 4, 2000, Pages 621-630

  Crawford, Jane H ^a   Wainwright, Anna ^a   Heavens, Robert ^a   Pollock, Jamie ^b   Martin, Duncan J ^b   Scott, Roderick H ^b   Seabrook, Guy R ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b Institute of Medical Science   (United Kingdom)

Author keywords

Intracellular calcium; Metabotropic glutamate receptors; Sensory neurones

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 1 AMINO 1,5 INDANDICARBOXYLIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CALCIUM; DANTROLENE; DIZOCILPINE; FURA 2; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; GLYCINE DERIVATIVE; IONOTROPIC RECEPTOR; METABOTROPIC RECEPTOR; RYANODINE; 1-AMINO-1,3-DICARBOXYCYCLOPENTANE; 1-AMINOINDAN-1,5-DICARBOXYLIC ACID; 2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 CHLORO 5 HYDROXYPHENYLGLYCINE; 2-(2,3-DICARBOXYCYCLOPROPYL)GLYCINE; 2-CHLORO-5-HYDROXYPHENYLGLYCINE; CALCIUM CHANNEL BLOCKING AGENT; CYCLOLEUCINE; CYCLOPROPANE DERIVATIVE; DRUG DERIVATIVE; GLYCINE; INDAN DERIVATIVE; MESSENGER RNA; METABOTROPIC RECEPTOR 5; PHENYLACETIC ACID DERIVATIVE; RYANODINE RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM MOBILIZATION; CELL SUBPOPULATION; CONTROLLED STUDY; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE CELL; SPINAL GANGLION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; FLUORESCENCE; METABOLISM; NEWBORN; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STEREOISOMERISM; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; CYCLOLEUCINE; CYCLOPROPANES; DANTROLENE; FLUORESCENCE; GANGLIA, SPINAL; GLUTAMIC ACID; GLYCINE; INDANS; PHENYLACETATES; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; STEREOISOMERISM;

EID: 0033625082     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00167-7     Document Type: Article

References (33)

1. Ascher P., Nowak L. Quisqualate- and kainate-activated channels in mouse cortical neurones in culture. Journal of Physiology. 399:1988;227-245.
2. 2+ release. Naunyn-Schmiedebergs Archiv für Pharmakologie. 359:1999;81-91.
3. Battaglia G., Rustioni A., Altschuler R.A., Petrusz P. Glutamic acid coexists with substance P in some primary sensory neurones. Schmidt R.F., Scaible H-G., Vahle-Hinz C. Fine Afferent Nerve Fibers and Pain. 1987;Verlagsgesellschaft, Germany. 479 pp.
4. 2+-dependent currents in dorsal root ganglion neurons by metabotropic glutamate receptors and cyclic ADP-ribose precursors. Journal of Neurophysiology. 77:1997;2573-2584.
5. - currents in cultured rat sensory neurones by flash photolysis of DM-nitrophen. Journal of Physiology. 482(2):1995;291-307.
6. Doherty A.J., Palmer M.J., Henley J.M., Collingridge G.L., Jane D.E. (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology. 36:1997;265-267.
7. 3H]-glutamate into neurons and satellite cells of dorsal root ganglia in vitro. Neuroscience. 8:1983;861-866.
8. Ferreira S.H., Lorenzetti B.B. Glutamate spinal retrograde sensitization of primary sensory neurons associated with nociception. Neuropharmacology. 33(11):1994;1479-1485.
9. Gereau R.W., Heinemann S.F. Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5. Neuron. 20:1998;143-151.
10. Grynkiewicz G., Poenie M., Tsien R.Y. A new generation of Ca indicators with greatly improved fluorescence properties. Journal of Biological Chemistry. 260:1985;3440-3450.
11. Ishida M., Saitoh T., Shimamoto K., Ohfune Y., Shinozaki H. A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord. British Journal of Pharmacology. 109:1993;1169-1177.
12. Johnson J.L., Aprison M.H. The distribution of glutamic acid, a transmitter candidate, and other amino acids in the dorsal sensory neurons of the cat. Brain Research. 24:1970;285-292.
13. Kawabata S., Tsutsumi R., Kohara A., Yamaguchi T., Nakanishi S., Okada M. Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature. 383:1996;89-92.
14. Meller S.T., Dykstra C.L., Gebhart G.F. Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors. Neuroreport. 4(7):1993;879-882.
15. Minakami R., Jinnai N., Sugiyama H. Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro. Journal of Biological Chemistry. 272:1997;20291-20298.
16. Nakahara K., Okada M., Nakanishi S. The metabotropic glutamate receptor mGluR5 induces calcium oscillations in cultured astrocytes via protein kinase C phosphorylation. Journal of Neurochemistry. 69:1997;1467-1475.
17. Nakanishi S. Molecular diversity of glutamate receptos and implications for brain functions. Science. 258:1992;597-603.
18. Nicoletti F., Casabona G., Genazzani A.A., L'Episcopo M.R., Shinozaki H. (2s,1′R,2′R,3′R)-2-(2,3-Dicarboxycyclopropyl) glycine enhances quisqualate-stimulated inositol phospholipid hydrolysis in hippocampal slices. European Journal of Pharmacology. 245:1993;297-308.
19. Nolan M.F., Logan S.D. Metabotropic glutamate receptor-mediated excitation and inhibition of sympathetic preganglionic neurones. Neuropharmacology. 37:1998;13-24.
20. Okamoto T., Sekiyama N., Otsu M., Shimada Y., Sato A., Nakanishi S., Jingami H. Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1. Journal of Biological Chemistry. 273:1998;13089-13096.
21. Palecek J., Paleckova V., Dougherty P.M., Willis W.D. The effect of trans-ACPD, a metabotropic excitatory amino acid receptor agonist, on the responses of primate spinothalamic tract neurons. Pain. 56(3):1994;261-269.
22. Pellicciari R., Luneia R., Constantino G., Marinozzi M., Natalini B., Jakobsen P., Kanstrup A., Lombardi G., Moroni F., Thomsen C. 1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. Journal of Medical Chemistry. 38:1995;3717-3719.
23. Pin J-P., Duvoisin R. The metabotropic glutamate receptors: Structure and functions. Neuropharmacology. 34:1995;1-26.
24. Pin J-P., Fagni L., Bockaert J. Metabotropic glutamate receptors: targets for new neuropharmacologically active drugs. Current Drugs: Neurodegenerative Disorders. 1:1993;111-137.
25. 2+ from the same store in cultured DRG neurones. Cell Calcium. 26:1999;139-148.
26. Salt T.E., Hill R.G. Neurotransmitter candidates of somatosensory primary afferent fibers. Neuroscience. 10:1983;1083-1103.
27. Schoepp D.D., Conn P.J. Metabotropic glutamate receptors in brain function and pathology. Trends in Pharmacological Sciences. 14:1993;13-20.
28. Schoepp D.D., Salhoff C.R., Wright R.A., Johnson B.G., Burnett J.P., Mayne N.G., Belagaje R., Wu S., Monn J.A. The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors. Neuropharmacology. 35:1996;1661-1672.
29. Seeburg P.H. The TIPS/TINS lecture: the molecular biology of mammalian glutamate receptor channels. Trends in Pharmacological Sciences. 14:1993;297-303.
30. Spanswick D., Pickering A.E., Gibson I.C., Logan S.D. Excitation of sympathetic preganglionic neurones via metabotropic excitatory amino acid receptor agonists. Neuroscience. 68:1995;1247-1261.
31. Thayer S.A., Perney T.M., Miller R.J. Regulation of calcium homeostasis in sensory neurons by bradykinin. Journal of Neuroscience. 8:1988;4089-4097.
32. Valerio A., Rizzonelli P., Paterlini M., Mretto G., Knopfel T., Memo M., Spano P. mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. Neuroscience Research. 28:1997;49-57.
33. Young M.R., Fleetwood-Walker S.M., Mitchell R., Dickinson T. The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons. Neuropharmacology. 34(8):1995;1033-1041.