Metabotropic glutamate receptor-mediated excitation and inhibition of sympathetic preganglionic neurones

Neuropharmacology

Volumn 37, Issue 1, 1998, Pages 13-24

  Nolan, M F ^a   Logan, S D ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Metabotropic glutamate receptors; Oscillations; Phenylglycines; Preganglionic neurone; Sympathetic control

Indexed keywords

2 (CARBOXYCYCLOPROPYL)GLYCINE; 4 CARBOXY 3 HYDROXYPHENYLGLYCINE; CYCLOLEUCINE; GLUTAMATE RECEPTOR AGONIST;

ANIMAL TISSUE; ARTICLE; DEPOLARIZATION; DOSE RESPONSE; DRUG EFFECT; DRUG RECEPTOR BINDING; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SYMPATHETIC NERVE;

AMINO ACIDS, DICARBOXYLIC; ANIMALS; AUTONOMIC FIBERS, PREGANGLIONIC; CYCLOLEUCINE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SPINAL CORD;

EID: 0031808557     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(97)00192-5     Document Type: Article

References (41)

1. Arnolda L.F., Pilowsky P.M., Minson J.B., Llewellyn-Smith I.J., Chalmers J.P. Tachycardia after glutamate injection in rat spinal cord is not mimicked by metabotropic agonists. Clin. Exp. Pharmacol. Physiol. 23:1996;813-818.
2. Baskys A. Metabotropic receptors and 'slow' excitatory actions of glutamate agonists in the hippocampus. Trends Neurosci. 15:1992;92-95.
3. Batchelor A.M., Madge D.J., Garthwaite J. Synaptic activation of metabotropic glutamate receptors in the parallel fiber-Purkinje cell pathway in rat cerebellar slices. Neuroscience. 63:1994;911-915.
4. Brabet I., Mary S., Bockaert J., Pin J.-P. Phenglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses. Neuropharmacology. 34:1995;895-903.
5. Cabot, J.B., 1990. Sympathetic preganglionic neurones: cytoarchitecture, ultrastructure and biophysical properties. In: Loewy, A.D., Spyer, K.M. (Eds.), Central Regulation of Autonomic Functions. Press at Oxford University Press, Oxford, pp. 44-67.
6. Coote J.H. The organisation of cardiovascular neurons in the spinal cord. Rev. Physiol. Biochem. Pharmacol. 110:1988;147-285.
7. Davies C.H., Clarke V.J., Jane D.E., Collingridge G.L. Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones. Br. J. Pharmacol. 116:1995;1859-1869.
8. Deuchars S.A., Morrison S.F., Gilbey M.P. Medullary-evoked EPSPs in neonatal rat sympathetic preganglionic neurones in vitro. J. Physiol. 487:1995;453-463.
9. Doherty A.J., Palmer M.J., Henley J.M., Collingridge G.L., Jane D.E. (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu(5), but not mGlu(1), receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology. 36:1997;265-267.
10. Forehand C.J. Morphology of sympathetic preganglionic neurones in the spinal cord: an intracellular horseradish peroxidase study. J. Comp. Neurol. 298:1990;334-342.
11. Gereau R.W., Conn P.J. Roles of specific metabotropic glutamate receptor subtypes in regulation of CA1 pyramidal cell excitability. J. Neurophysiol. 74:1995;122-129.
12. Glaum S.R., Miller R.J. Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract. J. Neurosci. 12:1992;2251-2258.
13. Hayashi Y., Sekiyama N., Nakanishi S., Jane D.E., Sunter D.C., Birse E.F., Udvarhelyi P.M., Watkins J.C. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J. Neurosci. 14:1994;3370-3377.
14. Hayashi Y., Tanabe Y., Aramori I., Masu M., Shimamoto K., Ohfune Y., Nakanishi S. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in chinese hamster ovary cells. Br. J. Pharmacol. 107:1992;539-543.
15. Holmes K.H., Keele N.B., Arvanov V.L., Shinnick-Gallagher P. Metabotropic glutamate receptor agonist-induced hyperpolarizations in rat basolateral amygdala neurons: receptor characterization and ion channels. J. Neurophysiol. 76:1996;3059-3069.
16. Inokuchi H., Yoshimura M., Yamada S., Polosa C., Nishi S. Fast excitatory postsynaptic potentials and the responses to excitant amino-acids of sympathetic preganglionic neurons in the slice of the cat spinal cord. Neuroscience. 46:1992;657-667.
17. Ito I., Kohda A., Tanabe S., Hirose E., Hayashi M., Mitsunaga S., Sugiyama H. 3,5-dihydroxyphenylglycine: a potent agonist of metabotropic glutamate receptors. NeuroReport. 3:1992;1013-1016.
18. Joly C., Gomeza J., Brabet I., Curry K., Bockaert J., Pin J.-P. Molecular, functional and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J. Neurosci. 15:1995;3970-3981.
19. Kingston A.E., Burnett J.P., Mayne N.G., Lodge D. Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1α and mGluR5a subtypes. Neuropharmacology. 34:1995;887-894.
20. Krupp J., Feltz P. Excitatory postsynaptic currents and glutamate receptors in neonatal rat sympathetic preganglionic neurons in vitro. J. Neurophysiol. 73:1995;1503-1512.
21. Llewellyn-Smith I.J., Minson J.B., Pilowsky P.M., Arnolda L.F., Chalmers J.P. The 100-percent hypothesis-glutamate or GABA in synapses on sympathetic preganglionic neurons. Clin. Exp. Hypertension. 17:1995;323-333.
22. Llewellyn-Smith I.J., Phend K.D., Minson J.B., Pilowsky P.M., Chalmers J.P. Glutamate-immunoreactive synapses on retrogradelly-labelled sympathetic preganglionic neurons in rat thoracic spinal cord. Brain Res. 581:1992;67-80.
23. Logan S.D., Pickering A.E., Gibson I.C., Nolan M.F., Spanswick D. Electrotonic coupling between rat sympathetic preganglionic neurones in vitro. J. Physiol. 495:1996;491-502.
24. Minson J., Pilowsky P., Llewellyn-Smith I., Kaneko T., Kapoor V., Chalmers J. Glutamate in spinally projecting neurons of the rostral ventral medulla. Brain Res. 555:1991;326-331.
25. Morrison S.F., Callaway J., Milner T.A., Reis D.J. Rostral ventrolateral medulla: a source of the glutamatergic innervation of the sympathetic intermediolateral nucleus. Brain Res. 562:1991;126-135.
26. Nakajima Y., Iwakabe H., Akazawa C., Nawa H., Shigemoto R., Mizuno N., Nakanishi S. Molecular charachterisation of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem. 268:1993;11868-11873.
27. Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science. 258:1992;597-603.
28. Nolan M.F., Logan S.D. Glutamate induced membrane potential oscillations in sympathetic preganglionic neurones from rat spinal cord in vitro. J. Physiol. 481:1994;8P.
29. Nolan M.F., Logan S.D. Actions of metabotropic glutamate receptor agonists and antagonists on sympathetic preganglionic neurones. Brain Res. Assoc. Abstr. 13:1996;77.
30. Pickering A.E., Spanswick D., Logan S.D. Whole-cell recordings from sympathetic preganglionic neurons in rat spinal cord slices. Neurosci. Letts. 130:1991;237-242.
31. Pin J.-P., Duvoisin R. The metabotropic glutamate receptors: structure and function. Neuropharmacology. 34:1995;1-26.
32. Pin J.-P., Joly C., Heinemann S.F., Bockaert J. Domains involved in the specificty of G protein activation in phospholipase C coupled metabotropic glutamate receptors. EMBO J. 13:1994;342-348.
33. Pook P.C.-K., Sunter D.C., Udvarhelyi P.M., Watkins J.C. Evidence for preynaptic depression of monosynaptic excitation in neonatal rat motoneurones by (1S,3S)- and (1S,3R)-ACPD. Exp. Physiol. 77:1992;529-532.
34. Pozzo Miller L.D., Petrozzino J.J., Connor J.A. G protein-coupled receptors mediate a fast excitatory postsynaptic current in CA3 pyramidal neurones in hippocampal slices. J. Neurosci. 15:1995;8320-8330.
35. Saugstad J.A., Kinzie J.M., Shinohara M.M., Segerson T.P., Westbrook G.L. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Mol. Pharmacol. 51:1997;119-125.
36. Schoepp D.D., Goldsworthy J., Johnson B.G., Salhoff C.R., Baker S.R. 3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. J. Neurochem. 63:1994;769-772.
37. Sekiyama N., Hayashi Y., Nakanishi S., Jane D.E., Tse H.-W., Birse E.F., Watkins J.C. Structure activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br. J. Pharmacol. 117:1996;1493-1503.
38. Spanswick D., Logan S.D. Sympathetic preganglionic neurones in neonatal rat spinal cord in vitro: electrophysiological charachteristics and the effects of selective excitatory amino acid receptor agonists. Brain Res. 525:1990;181-188.
39. Spanswick D., Pickering A.E., Gibson I.C., Logan S.D. Excitation of sympathetic preganglionic neurones via metabotropic excitatory amino acid receptors. Neuroscience. 68:1995;1247-1261.
40. Watkins J., Collingridge G. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends Pharmacol. 15:1994;333-342.
41. Wu S.Y., Dun N.J. Excitatory amino-acids depress synaptic currents in neonate rat sympathetic preganglionic neurons. J. Neurophysiol. 69:1993;2030-2038.