The stable pyrimidines UDPβS and UTPγS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery

British Journal of Pharmacology

Volumn 131, Issue 1, 2000, Pages 51-56

  Malmsjö, Malin ^a   Adner, Mikael ^a   Harden, T Kendall ^b   Pendergast, William ^c   Edvinsson, Lars ^a   Erlinge, David ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

P2 receptors; Purine; Pyrimidine; UDP S; UTP S; Vascular reactivity; Vasocontraction; Vasorelaxation

Indexed keywords

ACETYLCHOLINE; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; ADENOSINE 5' O 3 THIOTRIPHOSPHATE; ADENOSINE 5' O THIODIPHOSPHATE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE DIPHOSPHATE; LINSIDOMINE; NORADRENALIN; NUCLEOTIDASE; PURINE P2 RECEPTOR; PURINE P2X RECEPTOR; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; PYRIMIDINE DERIVATIVE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; URIDINE 5' O 3 THIOTRIPHOSPHATE; URIDINE 5' O THIODIPHOSPHATE; DRUG DERIVATIVE; NUCLEOTIDE; URIDINE 5' O (3 THIOTRIPHOSPHATE); URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE; URIDINE-5'-O-(3-THIOTRIPHOSPHATE);

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; ENZYME ACTIVITY; FEMALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION; ANIMAL; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MESENTERIC ARTERIES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2; THIONUCLEOTIDES; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE; VASOCONSTRICTION; VASODILATION;

EID: 0033624452     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703536     Document Type: Article

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