Enzymatic synthesis of UTPγS, a potent hydrolysis resistant agonist of P2U-purinoceptors

British Journal of Pharmacology

Volumn 117, Issue 1, 1996, Pages 203-209

  Lazarowski, Eduardo R ^a   Watt, William C ^a   Stutts, M Jackson ^a   Brown, H Alex ^b   Boucher, Richard C ^a   Harden, T Kendall ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cystic fibrosis; Nucleoside diphosphate kinase; P2U purinoceptors; UTP S

Indexed keywords

ACID PHOSPHATASE; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); ALKALINE PHOSPHATASE; APYRASE; CHLORIDE ION; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INOSITOL PHOSPHATE; NUCLEOSIDE DIPHOSPHATE KINASE; PHOSPHOROTHIOIC ACID; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; SULFUR 35; TRITIUM; UNCLASSIFIED DRUG; URIDINE 5' O (3 THIOTRIPHOSPHATE); URIDINE DERIVATIVE; URIDINE TRIPHOSPHATE;

ARTICLE; ASTROCYTOMA CELL; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG ACTIVITY; DRUG STABILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; ISOTOPE LABELING; NOSE MUCOSA; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE METABOLISM; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL;

ASTROCYTOMA; CHLORIDES; CYSTIC FIBROSIS; EPITHELIUM; HUMANS; INOSITOL PHOSPHATES; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANE POTENTIALS; NASAL CAVITY; RECEPTORS, PURINERGIC; THIONUCLEOTIDES; TUMOR CELLS, CULTURED; URIDINE TRIPHOSPHATE;

EID: 0029671012     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15175.x     Document Type: Article

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