The 5-HT3 agent N-(3-chlorophenyl)guanidine (MD-354) serves as a discriminative stimulus in rats and displays partial agonist character in a shrew emesis assay

Psychopharmacology

Volumn 150, Issue 2, 2000, Pages 200-207

  Dukat, Malgorzata ^a   Young, Richard ^a   Darmani, Nissar N ^b   Ahmed, Basnir ^b   Glennon, Richard A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b A T STILL UNIVERSITY   (United States)

Author keywords

2 Methyl 5 HT; Arylbiguanides; Arylguanidines; Emesis; mCPBG; Partial agonist; Quipazine

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; 2 METHYLSEROTONIN; GUANIDINE DERIVATIVE; MD 354; N (3 CHLOROPHENYL)GUANIDINE; QUIPAZINE; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; TROPISETRON; UNCLASSIFIED DRUG; ZACOPRIDE; SEROTONIN 3 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; DRUG EFFECT; DRUG SCREENING; FEMALE; INSECTIVORE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VOMITING; ANIMAL; CHEMICALLY INDUCED DISORDER; DISCRIMINATION LEARNING; PHYSIOLOGY; SHREW; SPRAGUE DAWLEY RAT;

ANIMALS; DISCRIMINATION LEARNING; FEMALE; GUANIDINES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SHREWS; VOMITING;

EID: 0033623951     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130000410     Document Type: Article

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