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Volumn 55, Issue 2, 2000, Pages 192-198

Defective regulation of IFNγ and IL-12 by endogenous IL-10 in progressive MS

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 12;

EID: 0033623923     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.55.2.192     Document Type: Article
Times cited : (65)

References (34)
  • 1
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-173.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 2
  • 3
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete G, De Carli M, Almerigogna F, et al. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 1993;150:353-360.
    • (1993) J Immunol , vol.150 , pp. 353-360
    • Del Prete, G.1    De Carli, M.2    Almerigogna, F.3
  • 4
    • 0029984051 scopus 로고    scopus 로고
    • Interleukin-12 primes human CD4 and CD8 T-cell clones for high production of both interferon-γ and interleukin-10
    • Gerosa F, Paganin C, Peritt D, et al. Interleukin-12 primes human CD4 and CD8 T-cell clones for high production of both interferon-γ and interleukin-10. J Exp Med 1996;183:2559-2569.
    • (1996) J Exp Med , vol.183 , pp. 2559-2569
    • Gerosa, F.1    Paganin, C.2    Peritt, D.3
  • 5
    • 0030002449 scopus 로고    scopus 로고
    • IL-12 synergizes with IL-2 and other stimuli in inducing IL-10 production by human T cells
    • Jeannin P, Delneste Y, Seveso M, et al. IL-12 synergizes with IL-2 and other stimuli in inducing IL-10 production by human T cells. J Immunol 1996;156:3159-3165.
    • (1996) J Immunol , vol.156 , pp. 3159-3165
    • Jeannin, P.1    Delneste, Y.2    Seveso, M.3
  • 6
    • 0030210830 scopus 로고    scopus 로고
    • IL-12 induces human T-cells secreting IL-10 with IFN-γ
    • Windhagen A, Anderson D, Carrizosa A, et al. IL-12 induces human T-cells secreting IL-10 with IFN-γ. J Immunol 1996; 157:1127-1131.
    • (1996) J Immunol , vol.157 , pp. 1127-1131
    • Windhagen, A.1    Anderson, D.2    Carrizosa, A.3
  • 8
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu Rev Immunol 1995; 13:251-276.
    • (1995) Annu Rev Immunol , vol.13 , pp. 251-276
    • Trinchieri, G.1
  • 10
    • 0023794099 scopus 로고
    • Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?
    • Beck J, Rondot P, Catinot L, et al. Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations? Acta Neurol Scand 1988;78:318-323.
    • (1988) Acta Neurol Scand , vol.78 , pp. 318-323
    • Beck, J.1    Rondot, P.2    Catinot, L.3
  • 11
    • 0023126661 scopus 로고
    • Exacerbations of multiple sclerosis in patients treated with gamma interferon
    • Panitch HS, Hirsch RL, Haley AS, et al. Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1987;1:893.
    • (1987) Lancet , vol.1 , pp. 893
    • Panitch, H.S.1    Hirsch, R.L.2    Haley, A.S.3
  • 12
    • 0027845224 scopus 로고
    • Cytokine mRNA expression in inflammatory multiple sclerosis lesions: Detection by non-radioactive in situ hybridization
    • Woodroofe MN, Cuzner ML. Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization. Cytokine 1993;5:583-588.
    • (1993) Cytokine , vol.5 , pp. 583-588
    • Woodroofe, M.N.1    Cuzner, M.L.2
  • 13
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
    • Windhagen A, Newcombe J, Dangond F, et al. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J Exp Med 1995;182:1985-1996.
    • (1995) J Exp Med , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3
  • 14
    • 0027366326 scopus 로고
    • Interferon b decreases T-cell activation and interferon γ production in multiple sclerosis
    • Noronha A, Toscas A, Jensen MA. Interferon b decreases T-cell activation and interferon γ production in multiple sclerosis. J Neuroimmunol 1993;46:145-153.
    • (1993) J Neuroimmunol , vol.46 , pp. 145-153
    • Noronha, A.1    Toscas, A.2    Jensen, M.A.3
  • 16
    • 0028913137 scopus 로고
    • Increased mRNA expression of IL-10 in mononuclear cells in multiple sclerosis and optic neuritis
    • Navikas V, Link J, Palasik W, et al. Increased mRNA expression of IL-10 in mononuclear cells in multiple sclerosis and optic neuritis. Scand J Immunol 1995;41:171-178.
    • (1995) Scand J Immunol , vol.41 , pp. 171-178
    • Navikas, V.1    Link, J.2    Palasik, W.3
  • 17
    • 0031453594 scopus 로고    scopus 로고
    • Cytokine mRNA expression in CSF and peripheral blood mononuclear cells in multiple sclerosis: Detection by RT-PCR without in vitro stimulation
    • Monteyne P, Van Laere V, Marichal R, et al. Cytokine mRNA expression in CSF and peripheral blood mononuclear cells in multiple sclerosis: detection by RT-PCR without in vitro stimulation. J Neuroimmunol 1997;80:137-142.
    • (1997) J Neuroimmunol , vol.80 , pp. 137-142
    • Monteyne, P.1    Van Laere, V.2    Marichal, R.3
  • 18
    • 0028807583 scopus 로고
    • Alterations in peripheral blood mononuclear cell cytokine production in response to phytohemagglutinin in multiple sclerosis patients
    • Crucian B, Dunne P, Friedman H, et al. Alterations in peripheral blood mononuclear cell cytokine production in response to phytohemagglutinin in multiple sclerosis patients. Clin Diagn Lab Immunol 1995;2:766-769.
    • (1995) Clin Diagn Lab Immunol , vol.2 , pp. 766-769
    • Crucian, B.1    Dunne, P.2    Friedman, H.3
  • 19
    • 0031214297 scopus 로고    scopus 로고
    • + T cell IL-10 production in stable relapsing multiple sclerosis
    • + T cell IL-10 production in stable relapsing multiple sclerosis. Int J Neurosci 1997;90:187-202.
    • (1997) Int J Neurosci , vol.90 , pp. 187-202
    • Brod, S.A.1    Nelson, L.D.2    Khan, M.3
  • 20
    • 0028985320 scopus 로고
    • Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
    • Rieckmann P, Albrecht M, Kitze B, et al. Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 1995;37:82-88.
    • (1995) Ann Neurol , vol.37 , pp. 82-88
    • Rieckmann, P.1    Albrecht, M.2    Kitze, B.3
  • 21
    • 0030112474 scopus 로고    scopus 로고
    • Interferon beta-1b effects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis
    • Byskosh PV, Reder AT. Interferon beta-1b effects on cytokine mRNA in peripheral mononuclear cells in multiple sclerosis. Mult Scler 1996;1:262-269.
    • (1996) Mult Scler , vol.1 , pp. 262-269
    • Byskosh, P.V.1    Reder, A.T.2
  • 22
    • 0032402229 scopus 로고    scopus 로고
    • IL-10 is required for development of protective Th1 responses in IL-12-deficient mice upon Candida albicans infection
    • Mencacci A, Cenci E, Del Sero G, et al. IL-10 is required for development of protective Th1 responses in IL-12-deficient mice upon Candida albicans infection. J Immunol 1998;161: 6228-6237.
    • (1998) J Immunol , vol.161 , pp. 6228-6237
    • Mencacci, A.1    Cenci, E.2    Del Sero, G.3
  • 25
    • 0027422997 scopus 로고
    • Interferon gamma and IL-4 secreting cells in multiple sclerosis
    • Lu C-Z, Jensen M, Arnason B. Interferon gamma and IL-4 secreting cells in multiple sclerosis. J Neuroimmunol 1993;46: 123-128.
    • (1993) J Neuroimmunol , vol.46 , pp. 123-128
    • Lu, C.-Z.1    Jensen, M.2    Arnason, B.3
  • 26
    • 0028095562 scopus 로고
    • Increased TGF beta, IL-4, and interferon gamma in multiple sclerosis
    • Link J, Soderstrom M, Olsson T, et al. Increased TGF beta, IL-4, and interferon gamma in multiple sclerosis. Ann Neurol 1994;36:379-386.
    • (1994) Ann Neurol , vol.36 , pp. 379-386
    • Link, J.1    Soderstrom, M.2    Olsson, T.3
  • 27
    • 0004882072 scopus 로고    scopus 로고
    • Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis
    • Nicoletti F, Patti F, Cocuzza C, et al. Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis. J Neuroimmunol 1996;70:87-90.
    • (1996) J Neuroimmunol , vol.70 , pp. 87-90
    • Nicoletti, F.1    Patti, F.2    Cocuzza, C.3
  • 29
    • 0028797606 scopus 로고
    • IL-12 reverses cytokine and immune abnormalities in Sezary syndrome
    • Rook AH, Kubin M, Cassin M, et al. IL-12 reverses cytokine and immune abnormalities in Sezary syndrome. J Immunol 1995;154:1491-1498.
    • (1995) J Immunol , vol.154 , pp. 1491-1498
    • Rook, A.H.1    Kubin, M.2    Cassin, M.3
  • 30
    • 0030639620 scopus 로고    scopus 로고
    • Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40
    • DeKruyff RH, Gieni RS, Umetsu DT. Antigen-driven but not lipopolysaccharide-driven IL-12 production in macrophages requires triggering of CD40. J Immunol 1997;158:359-366.
    • (1997) J Immunol , vol.158 , pp. 359-366
    • DeKruyff, R.H.1    Gieni, R.S.2    Umetsu, D.T.3
  • 31
    • 0029025420 scopus 로고
    • Down-regulating effects of IL-4 and IL-10 on the IFN-γ response in atopic dermatitis
    • Lester MR, Hofer MF, Gately M, et al. Down-regulating effects of IL-4 and IL-10 on the IFN-γ response in atopic dermatitis. J Immunol 1995;154:6174-6181.
    • (1995) J Immunol , vol.154 , pp. 6174-6181
    • Lester, M.R.1    Hofer, M.F.2    Gately, M.3
  • 32
    • 0028963377 scopus 로고
    • Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production
    • Leung DY, Gately M, Trumble A, et al. Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J Exp Med 1995;181: 747-753.
    • (1995) J Exp Med , vol.181 , pp. 747-753
    • Leung, D.Y.1    Gately, M.2    Trumble, A.3
  • 33
    • 0032528896 scopus 로고    scopus 로고
    • Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy
    • Comabella M, Balashov K, Issazadeh S, Smith D, Weiner HL, Khory SJ. Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy. J Clin Invest 1998;102:671-678.
    • (1998) J Clin Invest , vol.102 , pp. 671-678
    • Comabella, M.1    Balashov, K.2    Issazadeh, S.3    Smith, D.4    Weiner, H.L.5    Khory, S.J.6
  • 34
    • 0032975730 scopus 로고    scopus 로고
    • Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
    • van Boxel-Dezaire AHH, Hoff SCJ, van Oosten BW, et al. Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann Neurol 1999;45:695-703.
    • (1999) Ann Neurol , vol.45 , pp. 695-703
    • Van Boxel-Dezaire, A.H.H.1    Hoff, S.C.J.2    Van Oosten, B.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.