Serum vascular endothelial growth factor (VEGF), a prognostic indicator in sarcoma and carcinoma patients

International Journal of Oncology

Volumn 10, Issue 2, 1997, Pages 333-337

  Heits, Frank ^a   Katschinski, Dörthe M ^a   Wiedemann, Günter J ^a   Weiss, Christoph ^a   Jelkmann, Wolfgang ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

carcinoma; chemotherapy; sarcoma; vascular endothelial growth factor; VEGF

Indexed keywords

CARBOPLATIN; ENDOTHELIAL CELL GROWTH FACTOR; ETOPOSIDE; IFOSFAMIDE; TUMOR MARKER;

ADULT; ANGIOGENESIS; ARTICLE; CANCER CHEMOTHERAPY; CARCINOMA; CLINICAL ARTICLE; ENDOTHELIUM; FEMALE; HUMAN; MALE; METASTASIS; PRIORITY JOURNAL; SARCOMA; TUMOR GROWTH;

EID: 0031051066     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.2.333     Document Type: Article

References (27)

1. Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82:4-6, 1990.
2. Liotta L, Kleinerman J and Saidel G: Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res 34: 997-1004, 1974.
3. Folkman J and Shing Y: Angiogenesis. J Biol Chem 267: 10931-10934, 1992.
4. Senger DR, van de Water L, Brown LF, et al: Vascular perme-ability factor (VPF, VEGF) in tumor biology. Cancer Metastasis Rev 12: 303-324, 1993.
5. Kolch W, Martiny-Baron G, Kieser A and Marmé D: Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis. Breast Cancer Res Treat 36: 139-155, 1995.
6. Dvorak HF, Brown LF, Detmer M and Dvorak AM: Vascular permeability factor vascular endothelial growth factor, microvascular hyperpermeability and angiogenesis. Am J Pathol 146: 1029-1039, 1995.
7. Connolly DT, Heuvelmann DM, Nelson R, et al: Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 84: 1470-1478, 1984.
8. Leung DW, Cachianes G, Kuang W-J, Goeddel DV and Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309, 1989.
9. Shweiki D, Itin A, Soffer D and Keshet E: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845, 1992.
10. Toi M, Kondo S, Suzuki H, et al: Quantitative analysis of vascular endothelial growth factor in primary breast cancer. Cancer 77: 1101-1106, 1996.
11. 121. Cancer Res 55: 5296-5301, 1995.
12. Melnyk O, Shuman MA and Kim KJ: Vascular endothelial growth factor promotes tumor disseminition by a mechanism distinct from its effect on primary tumor growth. Cancer Res 56: 921-924, 1996.
13. Fields K, Zorsky P, Hiemenz J, Kronish L and Elfenbein G: Ifosfamide, carboplatin and etopside: a new regimen with a broad spectrum of activity. J Clin Oncol 12: 544-552, 1994.
14. Wiedemann GJ, Robins HI, Gutsche S, et al: Ifosfamide, carboplatin and etoposide (ICE) combined with 41.8°C wholebody hyperthermia in patients with refractory sarcoma. Eur J Cancer 32A: 888-892, 1996.
15. Wiedemann GJ, Katschinski DM, Mcntzcl M, et al: Ifosfamide (IFO), carboplatin (CBDCA) and etoposide (VP 16) combined with Aquathcrm induced 41.8°C whole body hyperthermia (WBH) for refractory sarcoma. J Clin Oncol 14: 1751, 1996.
16. Pötgens AJG, Westphal HR, De Waal RMW and Ruiter DJ: The role of vascular permeability factor and basic fibroblast growth factor in tumor angiogenesis. Biol Chem Hoppe-Seyler 376: 57-70, 1995.
17. Kondo S, Asano M, Matsuo K, Ohmori I and Suzuki H: Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients. Biochem Biophys Acta 1221: 211-214, 1994.
18. Watanabe O, Arimura K, Kitajima I, Osame M and Maruyama I: Greatly raised vascular endothelial growth factor (VEGF) in POEMS syndrome. Lancet 347: 702, 1996.
19. Srivasta A, Laidler P, Hughes LE, Woodcock J and Shedden EJ: Neovascularization in human cutaneous melanoma: a quantitative morphological and Doppler ultrasound study. Eur J Cancer Clin Oncol 22: 1205-1209, 1986.
20. Weidner N, Semple JP, Welch WR and Folkman J: Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8, 1991.
21. Weidner N, Carroll PR, Flax J, Blumenfeld W and Folkman J: Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 143: 401-409, 1993.
22. Macchiarini P, Fontanini G, Hardin MJ, Squartini F and Angeletti CA: Relation of neovascularisation to metastasis of non-small cell lung cancer. Lancet 340: 145-146, 1992.
23. Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, Dvorak HF and Senger DR: Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am J Pathol 143: 1255-1262, 1993.
24. Takahashi Y, Kitadai Y, Bucana CD, Cleary KR and Ellis LM: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 55: 3964-3968, 1995.
25. O'Brien T, Cranston D, Fuggle S, Bicknell R and Harris AL: Different angiogenic pathways characterize superficial and invasive bladder cancer. Cancer Res 55: 510-513, 1995.
26. Brown LF, Berse B, Jackman RW, et al: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 26: 86-91, 1995.
27. Maeda K, Chung Y, Ogawa Y, et al: Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer 77: 858-863, 1996.