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Volumn 161, Issue 2, 2000, Pages 527-534

Aβ42-carboxy-terminal-like immunoreactivity is associated with intracellular neurofibrillary tangles and pick bodies

Author keywords

Alzheimer's disease; Elderly controls; Hippocampus; Immunostaining; Parkinsonism dementia complex of Guam; Pick disease; Progressive supranuclear palsy; Substantia nigra; 42 amyloid

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NEUROFIBRILLARY TANGLE; PARKINSONISM; PICK PRESENILE DEMENTIA; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; BRAIN; DEMENTIA; METHODOLOGY; MIDDLE AGED; NERVE CELL; PARKINSON DISEASE; PATHOLOGY; REFERENCE VALUE; ULTRASTRUCTURE;

EID: 0033621754     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7307     Document Type: Article
Times cited : (15)

References (19)
  • 1
    • 0030665870 scopus 로고    scopus 로고
    • Variable deposition of amyloid beta-protein (A beta) with the carboxy-terminus that ends at residue valine40 (A beta 40) in the cerebral cortex of patients with Alzheimer's disease: A double-labeling immunohistochemical study with antibodies specific for A beta 40 and the A beta that ends at residues alanine42/threonine43 (A beta 42)
    • Akiyama H., Mori H., Sahara N., Kondo H., Ikeda K., Nishimura T., Oda T., McGeer P L. Variable deposition of amyloid beta-protein (A beta) with the carboxy-terminus that ends at residue valine40 (A beta 40) in the cerebral cortex of patients with Alzheimer's disease: A double-labeling immunohistochemical study with antibodies specific for A beta 40 and the A beta that ends at residues alanine42/threonine43 (A beta 42). Neurochem. Res. 22:1997;1499-1506.
    • (1997) Neurochem. Res. , vol.22 , pp. 1499-1506
    • Akiyama, H.1    Mori, H.2    Sahara, N.3    Kondo, H.4    Ikeda, K.5    Nishimura, T.6    Oda, T.7    McGeer, P.L.8
  • 2
    • 0030003487 scopus 로고    scopus 로고
    • Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of β-amyloid protein
    • Akiyama H., Schwab C., Kondo H., Mori H., Kametani F., Ikeda K., McGeer P. L. Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of β-amyloid protein. Neurosci. Lett. 206:1996;169-172.
    • (1996) Neurosci. Lett. , vol.206 , pp. 169-172
    • Akiyama, H.1    Schwab, C.2    Kondo, H.3    Mori, H.4    Kametani, F.5    Ikeda, K.6    McGeer, P.L.7
  • 3
    • 0032551528 scopus 로고    scopus 로고
    • Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein
    • Bahr B. A., Hoffman K. B., Yang A. J., Hess U. S., Glabe C. G., Lynch G. Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein. J. Comp. Neurol. 397:1998;139-147.
    • (1998) J. Comp. Neurol. , vol.397 , pp. 139-147
    • Bahr, B.A.1    Hoffman, K.B.2    Yang, A.J.3    Hess, U.S.4    Glabe, C.G.5    Lynch, G.6
  • 4
    • 0029975481 scopus 로고    scopus 로고
    • Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease
    • Braak H., Braak E., Bohl J., Reintjes R. Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease. Neurosci. Lett. 210:1996;87-90.
    • (1996) Neurosci. Lett. , vol.210 , pp. 87-90
    • Braak, H.1    Braak, E.2    Bohl, J.3    Reintjes, R.4
  • 5
    • 0028986916 scopus 로고
    • Beta-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding
    • Busciglio J., Lorenzo A., Yeh J., Yanker B. A. beta-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron. 14:1995;879-888.
    • (1995) Neuron , vol.14 , pp. 879-888
    • Busciglio, J.1    Lorenzo, A.2    Yeh, J.3    Yanker, B.A.4
  • 11
    • 0026667044 scopus 로고
    • Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy
    • McGeer P. L., Akiyama H., Kawamata T., Yamada T., Walker D. G., Ishii T. Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy. J. Neurosci. Res. 31:1992;428-442.
    • (1992) J. Neurosci. Res. , vol.31 , pp. 428-442
    • McGeer, P.L.1    Akiyama, H.2    Kawamata, T.3    Yamada, T.4    Walker, D.G.5    Ishii, T.6
  • 13
    • 0031743331 scopus 로고    scopus 로고
    • Extracellular neurofibrillary tangles are immunopositive for the 40 carboxy-terminal sequence of β-amyloid protein
    • Schwab C., Akiyama H., McGeer E. G., McGeer P. L. Extracellular neurofibrillary tangles are immunopositive for the 40 carboxy-terminal sequence of β-amyloid protein. J. Neuropathol. Exp. Neurol. 57:1998;1131-1137.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 1131-1137
    • Schwab, C.1    Akiyama, H.2    McGeer, E.G.3    McGeer, P.L.4
  • 14
    • 0029164285 scopus 로고
    • Relationship of amyloid β/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia
    • Schwab C., Steele J., Akiyama H., McGeer E. G., McGeer P. L. Relationship of amyloid β/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia. Acta Neuropathol. 90:1995;287-298.
    • (1995) Acta Neuropathol. , vol.90 , pp. 287-298
    • Schwab, C.1    Steele, J.2    Akiyama, H.3    McGeer, E.G.4    McGeer, P.L.5
  • 15
    • 0031781642 scopus 로고    scopus 로고
    • Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture
    • Skovronsky D. M., Doms R. W., Lee V. M. Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture. J. Cell Biol. 141:1998;1031-1039.
    • (1998) J. Cell Biol. , vol.141 , pp. 1031-1039
    • Skovronsky, D.M.1    Doms, R.W.2    Lee, V.M.3
  • 16
    • 0025352340 scopus 로고
    • Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease
    • Spillantini M. G., Goedert M., Jakes R., Klug A. Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease. Proc. Natl. Acad. Sci. USA. 87:1990;3952-3956.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3952-3956
    • Spillantini, M.G.1    Goedert, M.2    Jakes, R.3    Klug, A.4
  • 17
    • 0025668429 scopus 로고
    • Amyloid beta/A4 protein precursor is bound to neurofibrillary tangles in Alzheimer-type dementia
    • Yamaguchi H., Ishiguro K., Shoji M., Yamazaki T., Nakazato Y., Ihara Y., Hirai S. Amyloid beta/A4 protein precursor is bound to neurofibrillary tangles in Alzheimer-type dementia. Brain Res. 537:1990;318-322.
    • (1990) Brain Res. , vol.537 , pp. 318-322
    • Yamaguchi, H.1    Ishiguro, K.2    Shoji, M.3    Yamazaki, T.4    Nakazato, Y.5    Ihara, Y.6    Hirai, S.7
  • 18
    • 0032526652 scopus 로고    scopus 로고
    • Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis
    • Yang A. J., Chandswangbhuvana D., Margol L., Glabe C. G. Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis. J. Neurosci. Res. 52:1998;691-698.
    • (1998) J. Neurosci. Res. , vol.52 , pp. 691-698
    • Yang, A.J.1    Chandswangbhuvana, D.2    Margol, L.3    Glabe, C.G.4
  • 19
    • 0342962687 scopus 로고    scopus 로고
    • Altered metabolism of the amyloid precursor protein and neurodegeneration in Down's syndrome
    • Yanker B. A., Wong C., Fernandez G., Yuan M., Mori H., Busciglio J. Altered metabolism of the amyloid precursor protein and neurodegeneration in Down's syndrome. Neurobiol. Aging. 19:1998;7.
    • (1998) Neurobiol. Aging , vol.19 , pp. 7
    • Yanker, B.A.1    Wong, C.2    Fernandez, G.3    Yuan, M.4    Mori, H.5    Busciglio, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.