Probing the salmeterol binding site on the β2-adrenergic receptor using a novel photoaffinity ligand, [125I]iodoazidosalmeterol

Biochemistry

Volumn 38, Issue 35, 1999, Pages 11278-11286

  Rong, Yajing ^a   Arbabian, Marty ^a   Thiriot, David S ^a   Seibold, Anita ^b   Clark, Richard B ^b   Ruoho, Arnold E ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ALPRENOLOL; AZIDE; BETA 2 ADRENERGIC RECEPTOR; IODINE 125; IODOAZIDOSALMETEROL; SALMETEROL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IODINATION; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

ADENYLATE CYCLASE; ALBUTEROL; ANIMALS; AZIDES; CELL LINE; CELL MEMBRANE; CELL-FREE SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; EPINEPHRINE; GUINEA PIGS; HUMANS; HYDROLYSIS; IODINE RADIOISOTOPES; LIGANDS; MUSCLE RELAXATION; PHOTOAFFINITY LABELS; RECEPTORS, ADRENERGIC, BETA-2; TRACHEA;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0033621049     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9910676     Document Type: Article

References (19)

1. Hockerman, G. H., Girvin, M. K., Malbon, C. C., and Ruoho, A. E. (1996) Mol. Pharmacol. 49, 1021-1032.
2. Johnson, M. (1995) Med. Res. Rev. 15, 225-257.
3. Clark, R. B., Allal, C., Friedman, J., Johnson, M., and Barber, R. (1996) Mol. Pharmacol. 49, 182-189.
4. January, B., Seibold, A., Allal, C., Whaley, B. S., Knoll, B. J., Moore, R. H., Dickey, B. F., Barber, R., and Clark, R. B. (1998) Br. J. Pharmacol. 123, 701-711.
5. Green, S. A., Spasoff, A. P., Coleman, R. A., Johnson, M., and Ligget, S. B. (1996) J. Biol. Chem 271, 24029-24035.
6. Anderson, G. P., Linden, A., and Rabo, K. F. (1994) Eur. Respir. J. 7, 569-578.
7. Rhodes, D. G., Newton, R., Butler, R., and Herbette, L. (1992) Mol. Pharmacol. 42, 596-602.
8. Lofdahl, C. (1990) Lung (Suppl.), 18-22.
9. Teschemacher, A., and Lemoine, H. (1999) J. Pharmacol. Exp. Ther. 288, 1084-1092.
10. Rong, Y., and Ruoho, A. E. (1999) Synth. Commun. 29, 2155.
11. Carroll, F. I., Gao, Y., Rahman, M., Abraham, P., Parham, K., Lewin, A., and Boja, J. (1991) J. Med. Chem. 34, 2719-2725.
12. Rashidbaigi, A., and Ruoho, A. E. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 1609-1613.
13. Wu, Z., and Ruoho, A. E., unpublished results.
14. Wong, L. K. F., Slaughter, C., Ruoho, A. E., and Ross, E. M. (1988) J. Biol. Chem. 263, 7925-7928.
15. Niais, A. T., Summer, M. J., Johnson, M., and Coleman, R. A. (1993) Br. J. Pharmacol. 108, 507-515.
16. Ball, D. I., Brittain, R. T., Coleman, R. A., Denyer, L. H., Jack, D., Johnson, M., Lunts, L. H. C., Nials, A. T., Sheldrick, K. E., and Skidmore, I. F. (1991) Br. J. Pharmacol. 104, 665-671.
17. Isogaya, M., Yamagiwa, Y., Fujita, S., Sugimoto, Y., Nagao, T., and Kurose, H. (1998) Mol. Pharmacol. 54, 616-622.
18. Donnelly, D., Findlay, J. B. C., and Blundell, T. L. (1994) Recept. Channels 2, 61-78.
19. Horn, F., Weare, J., Beukers, M. W., Hörsch, S., Bairoch, A., Chen, W., Edvardsen, Ø., Campagne, F., and Vriend, G. (1998) Nucleic Acids Res. 26, 277-281.