Asymmetric Solid-Phase Synthesis of (3′R,4′R)-Di-O-cis-acyl 3-Carboxyl Khellactones

Organic Letters

Volumn 1, Issue 13, 1999, Pages 2113-2115

  Xia, Yi ^a   Yang, Zheng Yu ^a   Brossi, Arnold ^a   Lee, Kuo Hsiung ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COUMARIN DERIVATIVE;

ACYLATION; ARTICLE; HYDROXYLATION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

ACYLATION; COUMARINS; HYDROXYLATION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY;

EID: 0033619848     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol991168w     Document Type: Article

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16. 3), 5.54 (d, J = 10.1 Hz, 1H, H-3), 6.36 (d. J = 8.4 Hz, 1H, H-8), 6.62 (d, J = 10.1 Hz, 1H, H-4), 7.21 (d, J = 8.4 Hz, 1H, H-7), 9.59 (s, 1H, aldehyde). Yield: 29.4%. Mp: 69-70°C.
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18. 1H NMR analysis of the bis-(-)-camphanic esters.
19. 2 for 2 h. All new compounds gave satisfactory analytical and spectroscopic data.