Serine 19 of human 6-pyruvoyltetrahydropterin synthase is phosphorylated by cGMP protein kinase II

Journal of Biological Chemistry

Volumn 274, Issue 44, 1999, Pages 31341-31348

  Scherer Oppliger, Tanja ^a   Leimbacher, Walter ^a   Blau, Nenad ^a   Thöny, Beat ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; DYSPROPTERIN; MUTANT PROTEIN; PROTEIN SERINE THREONINE KINASE; RECOMBINANT ENZYME; SERINE; SYNTHETASE; TETRAHYDROBIOPTERIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CODON; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME MODIFICATION; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING;

ALKALOIDS; AMINO ACID METABOLISM, INBORN ERRORS; AMINO ACID SEQUENCE; ANIMALS; CARBAZOLES; CONSENSUS SEQUENCE; COS CELLS; CYCLIC GMP-DEPENDENT PROTEIN KINASES; FIBROBLASTS; HUMANS; INDOLES; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORUS-OXYGEN LYASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SERINE; SKIN; STAUROSPORINE;

EID: 0033615638     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.44.31341     Document Type: Article

References (38)

1. Kaufman, S. (1993) Annu. Rev. Nutr. 13, 261-286
2. Blau, N., Thöny, B., Heizmann, C. W., and Dhondt, J.-L. (1993) Pteridines 4, 1-10
3. Scriver, C. R., Kaufman, S., Eisensmith, R. C., and Woo, S. L. C. (1995) in Metabolic and Molecular Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., eds) pp. 1015-1075, McGraw-Hill, New York
4. Blau, N., Barnes, I., and Dhondt, J. L. (1996) J. Inherited Metab. Dis. 19, 8-14
5. Thöny, B., and Blau, N. (1997) Hum. Mutat. 10, 11-20
6. Blau, N., Dhondt, J. L., Dianzani, I., and Thöny, B. (1997) in Chemistry and Biology of Pteridines and Folates (Pfleiderer, W., and Rokos, H., eds) pp. 719-726, Blackwell Science, Oxford
7. Oppliger, T., Thöny, B., Nar, H., Bürgisser, D., Huber, R., Heizmann, C. W., and Blau, N. (1995) J. Biol. Chem. 270, 29498-29506
8. Imazumi, K., Sasaki, T., Takahashi, K., and Takai, Y. (1994) Biochem. Biophys. Res. Commun. 205, 1409-1416
9. Lapize, C., Plüss, C., Werner, E. R., Huwiler, A., and Pfeilschifter, J. (1998) Biochem. Biophys. Res. Commun. 251, 802-805
10. Hesslinger, C., Kremmer, E., Hültner, L., Ueffing, M., and Ziegler, I. (1998) J. Biol. Chem. 273, 21616-21622
11. Katoh, S., Sueoka, T., Yamamoto, Y., and Takahashi, S. Y. (1994) FEBS Lett. 341, 227-232
12. Ziegler, I., Schott, K., Lübbert, M., Herrmann, F., Schwuléra, U., and Bacher, A. (1990) J. Biol. Chem. 265, 17026-17030
13. Werner, E. R., Werner-Felmayer, G., Fuchs, D., Hausen, A., Reibenegger, G., Yim, J. J., Pfleiderer, W., and Wachter, H. (1990) J. Biol. Chem. 265, 3189-3192
14. Ziegler, I., Hültner, L., Egger, D., Kemkes, B., Mailhammer, R., Gillis, S., and Rödl, W. (1993) J. Biol. Chem. 268, 12544-12551
15. Hirayama, K., and Kapatos, G. (1995) Neurochem. Int. 27, 157-161
16. D'Sa, C., Hirayama, K., West, A., Hahn, M., Zhu, M., and Kapatos, G. (1996) Mol. Brain Res. 41, 105-110
17. Stegenga, S. L., Hirayama, K., and Kapatos, G. (1996) J. Neurochem. 66, 2541-2545
18. Plüss, C., Werner, E. R., Blau, N., Wachter, H., and Pfeilschifter, J. (1996) Biochem. J. 318, 665-671
19. Zhu, M., Hirayama, K., and Kapatos, G. (1994) J. Biol. Chem. 269, 11825-11829
20. Thöny, B., Leimbacher, W., Bürgisser, D., and Heizmann, C. W. (1992) Biochem. Biophys. Res. Commun. 189, 1437-1443
21. Ruth, P., Pfeifer, A., Kamm, S, Klatt, P., Dostmann, W. R. G., and Hofmann, F. (1997) J. Biol. Chem. 272, 10522-10528
22. Bürgisser, D. M., Thöny, B., Redweik, U., Hunziker, P., Heizmann, C. W., and Blau, N. (1994) Eur. J. Biochem. 219, 497-502
23. Thöny, B., Leimbacher, W., Blau, N., Harvie, A., and Heizmann, C. W. (1994) Am. J. Hum. Genet. 54, 782-792
24. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1992) in Current Protocols in Molecular Biology, John Wiley & Sons, Inc., New York
25. Pfeifer, A., Aszodi, A., Seidler, U., Ruth, P., Hofmann, F., and Fässler, R. (1996) Science 274, 2082-2086
26. Pfeifer, A., Klatt, P., Massberg, S., Ny, L., Sausbier, M., Hirneiss, C., Wang, G.-X., Korth, M., Aszodi, A., Andersson, K.-E., Krombach, F., Mayerhofer, A., Ruth, P., Faessler, R., and Hofmann, F. (1998) EMBO J. 17, 3045-3051
27. Pearson, R. B., and Kemp, B. E. (1991) Methods Enzymol. 200, 62-81
28. Thöny, B., Leimbacher, W., Scherer-Oppliger, T., Heizmann, C. W., and Lau, N. (1997) in Chemistry and Biology of Pteridines and Folates (Pfleiderer, W., and Rokos, H., eds) pp. 713-718, Blackwell Science, Berlin, Vienna
29. Colbran, J. L., Francis, S. H., Leach, A. B., Thomas, M. K., Jiang, H., McAllister, L. M., and Corbin, J. D. (1992) J. Biol. Chem. 267, 9589-9584
30. Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murakata, C., Sato, A., and Kaneko, M. (1987) Biochem. Biophys. Res. Commun. 142, 436-440
31. Bürgisser, D., Thöny, B., Redweik, U., Hess, D., Heizmann, C. W., Huber, R., and Nar, H. (1995) J. Mol. Biol. 253, 358-369
32. Ploom, T., Thöny, B., Yim, J., Lee, S., Nar, H., Leimbacher, W., Richardson, J., Huber, R., and Auerbach, G. (1999) J. Mol. Biol. 286, 851-860
33. Hauer, C. R., Leimbacher, W., Hunziker, W., Neuheiser, F., Blau, N., and Heizmann, C. (1992) Biochem. Biophys. Res. Commun. 182, 953-959
34. Turri, M. O., Ilg, E. C., Thöny, B., and Blau, N. (1998) Biol. Chem. 379, 1441-1447
35. Lohmann, S. M., Vaandrager, A. B., Smolenski, A., Walter, U., and DeJonge, H. R. (1997) Trends Biochem. Sci. 22, 307-312
36. Fujii, M., Ogata, T., Takahashi, E., Yamada, K., Nakabayashi, K., Oishi, M., and Ayusawa, D. (1995) FEBS Lett. 375, 263-267
37. Orstavik, S., Solberg, R., Tasken, K., Nordahl, M., Altherr, M. R., Hansson, V., Jahnsen, T., and Sandberg, M. (1996) Biochem. Biophys. Res. Commun. 220, 759-765
38. Vandraager, A. B., Smolenski, A., Tilly, B. C., Houtsmuller, A. B., Ehlert, E. M. E., Bot, A. G. M., Edixhoven, M., Boomaars, W. E. M., Lohmann, S. M., and De Jonge, H. R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 1466-1471