메뉴 건너뛰기




Volumn 354, Issue 1389, 1999, Pages 1591-1599

Role of factors downstream of caspases in nuclear disassembly during apoptotic execution

Author keywords

Apoptosis; CAD; Caspases; DFF; ICAD

Indexed keywords

ANIMALIA; GALLUS GALLUS;

EID: 0033615330     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.1999.0503     Document Type: Article
Times cited : (5)

References (48)
  • 1
    • 0025247903 scopus 로고
    • Apoptosis: The role of the endonuclease
    • Arends, M. J., Morris, R. G. & Wyllie, A. H. 1990 Apoptosis: the role of the endonuclease. Am. J. Pathol. 136, 593-608.
    • (1990) Am. J. Pathol. , vol.136 , pp. 593-608
    • Arends, M.J.1    Morris, R.G.2    Wyllie, A.H.3
  • 2
    • 0030994024 scopus 로고    scopus 로고
    • Bel-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation
    • Boise, L. H. & Thompson, C. B. 1997 Bel-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation. Proc. Natl Acad. Sci. USA 94, 3759-3764.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 3759-3764
    • Boise, L.H.1    Thompson, C.B.2
  • 3
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. M. 1997 Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 4
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns, V. & Yuan, J. 1998 Proteases to die for. Genes Dev. 12, 1551-1570.
    • (1998) Genes Dev. , vol.12 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 5
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates and functions during apoptosis
    • In the press
    • Earnshaw, W. C., Martins, L. M. & Kaufmann, S. H. 1999 Mammalian caspases: structure, activation, substrates and functions during apoptosis. A. Rev. Biochem. 68. (In the press.)
    • (1999) A. Rev. Biochem. , vol.68
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 6
    • 0028805524 scopus 로고
    • Apoptosis by a cytosolic extract from Fas-activated cells
    • Enari, M., Hase, A. & Nagata, S. 1995 Apoptosis by a cytosolic extract from Fas-activated cells. EMBO J. 14, 5201-5208.
    • (1995) EMBO J. , vol.14 , pp. 5201-5208
    • Enari, M.1    Hase, A.2    Nagata, S.3
  • 7
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari, M., Sakahira, H., Yakoyama, H., Okawa, K., Iwamatsu, A. & Nagata, S. 1998 A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391, 43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yakoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 8
    • 0032493870 scopus 로고    scopus 로고
    • Differential requirement for caspase 9 in apoptotic pathways in vivo
    • Hakem, R. (and 15 others) 1998 Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94, 339-352.
    • (1998) Cell , vol.94 , pp. 339-352
    • Hakem, R.1
  • 10
    • 0028268215 scopus 로고
    • Programmed cell death and Bcl-2 protection in the absence of a nucleus
    • Jacobson, M. D., Burne, J. F. & Raff, M. C. 1994 Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J. 13, 1899-1910.
    • (1994) EMBO J. , vol.13 , pp. 1899-1910
    • Jacobson, M.D.1    Burne, J.F.2    Raff, M.C.3
  • 11
    • 0032546795 scopus 로고    scopus 로고
    • Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
    • Jänicke, R. U., Ng, P., Sprengart, M. L. & Porter, A. G. 1998a Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J. Biol. Chem. 273, 15 540-15 545.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15540-15545
    • Jänicke, R.U.1    Ng, P.2    Sprengart, M.L.3    Porter, A.G.4
  • 12
    • 0040298568 scopus 로고    scopus 로고
    • Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
    • Jänicke, R. U., Sprengart, M. L., Wati, M. R. & Porter, A. G. 1998b Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 273, 9357-9360.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9357-9360
    • Jänicke, R.U.1    Sprengart, M.L.2    Wati, M.R.3    Porter, A.G.4
  • 13
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myclogenous leukemin cells by ctoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann, S. H. 1989 Induction of endonucleolytic DNA cleavage in human acute myclogenous leukemin cells by ctoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res. 49, 5870-5878.
    • (1989) Cancer Res. , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 14
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer, G. 1997 The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Med. 3, 614-620.
    • (1997) Nature Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 15
    • 0029956641 scopus 로고    scopus 로고
    • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
    • Kuida, K., Zheng, T. S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P. & Flavell, R. A. 1996 Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384, 368-372.
    • (1996) Nature , vol.384 , pp. 368-372
    • Kuida, K.1    Zheng, T.S.2    Na, S.3    Kuan, C.4    Yang, D.5    Karasuyama, H.6    Rakic, P.7    Flavell, R.A.8
  • 17
    • 0032498630 scopus 로고    scopus 로고
    • E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk
    • Lavoic, J. N., Nguyen, M., Marcellus, R. C., Branton, P. E. & Shore, G. C. 1998 E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk. J. Cell Biol. 140, 637-645.
    • (1998) J. Cell Biol. , vol.140 , pp. 637-645
    • Lavoic, J.N.1    Nguyen, M.2    Marcellus, R.C.3    Branton, P.E.4    Shore, G.C.5
  • 18
    • 0027437541 scopus 로고
    • Nuclear events of apoptosis in vitro in cell-free mitotic extracts: A model system for analysis of the active phase of apoptosis
    • Lazebnik, V. A., Cole, S., Cooke, C. A., Nelson, W. G. & Earnshaw, W. C. 1993 Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis. J. Cell Biol. 123, 7-22.
    • (1993) J. Cell Biol. , vol.123 , pp. 7-22
    • Lazebnik, V.A.1    Cole, S.2    Cooke, C.A.3    Nelson, W.G.4    Earnshaw, W.C.5
  • 19
    • 0028102478 scopus 로고
    • Cleavage of poly(ADP-ribose) polymerase by a protease with properties like ICE
    • Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G. & Earnshaw, W. C. 1994 Cleavage of poly(ADP-ribose) polymerase by a protease with properties like ICE. Nature 371, 346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 21
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome C
    • Liu, X., Kim, C. N., Yang, J., Jemmerson, R. & Wang, X. 1996 Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome C. Cell 86, 147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 22
    • 0032555215 scopus 로고    scopus 로고
    • The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis
    • Liu, X., Li, P., Widlak, P., Zou, H., Luo, X., Garrard, W. T. & Wang, X. 1998 The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc. Natl Acad. Sci. USA 95, 8461-8466.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 8461-8466
    • Liu, X.1    Li, P.2    Widlak, P.3    Zou, H.4    Luo, X.5    Garrard, W.T.6    Wang, X.7
  • 23
    • 0030916417 scopus 로고    scopus 로고
    • DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • Liu, X., Zou, H., Slaughter C. & Wang, X. 1997 DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89, 175-184.
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4
  • 25
    • 0029802815 scopus 로고    scopus 로고
    • Phosphatidylserine externalization during cD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity
    • Martin, S. J., Finucane, D. M., Amarante-Mendes, G. P., O'Brien, G. A. & Green, D. R. 1996 Phosphatidylserine externalization during cD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity. J. Biol. Chem. 271, 28 753-28 756.
    • (1996) J. Biol. Chem. , vol.271 , pp. 28753-28756
    • Martin, S.J.1    Finucane, D.M.2    Amarante-Mendes, G.P.3    O'Brien, G.A.4    Green, D.R.5
  • 26
    • 0031033274 scopus 로고    scopus 로고
    • Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
    • McCarthy, N. J., Whyte, M. K., Gilbert, C. S. & Evan, G. I. 1997 Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell Biol. 136, 215-227.
    • (1997) J. Cell Biol. , vol.136 , pp. 215-227
    • McCarthy, N.J.1    Whyte, M.K.2    Gilbert, C.S.3    Evan, G.I.4
  • 28
    • 0028938366 scopus 로고
    • The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity
    • Nakajima, H., Golstein, P. & Henkart, P. A. 1995 The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity. J. Exp. Med. 181, 1905-1909.
    • (1995) J. Exp. Med. , vol.181 , pp. 1905-1909
    • Nakajima, H.1    Golstein, P.2    Henkart, P.A.3
  • 29
    • 0028019746 scopus 로고
    • Cell-free apoptosis in xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria
    • Newmeyer, D. D., Farschon, D. M. & Reed, J. C. 1994 Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 79, 353-364.
    • (1994) Cell , vol.79 , pp. 353-364
    • Newmeyer, D.D.1    Farschon, D.M.2    Reed, J.C.3
  • 31
    • 0031170966 scopus 로고    scopus 로고
    • Death substrates come alive
    • Porter, A. G., Ng, P. & Jänicke, R. U. 1997 Death substrates come alive. BioEssays 19, 501-507.
    • (1997) BioEssays , vol.19 , pp. 501-507
    • Porter, A.G.1    Ng, P.2    Jänicke, R.U.3
  • 32
    • 0029311281 scopus 로고
    • Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells
    • Rizzuto, R., Brini, M., Pizzo, P., Murgia, M. & Pozzan, T. 1995 Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr. Biol. 5, 635-642.
    • (1995) Curr. Biol. , vol.5 , pp. 635-642
    • Rizzuto, R.1    Brini, M.2    Pizzo, P.3    Murgia, M.4    Pozzan, T.5
  • 33
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira, H., Enari, M. & Nagata, S. 1998 Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391, 96-99.
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 34
    • 0032529915 scopus 로고    scopus 로고
    • ICAD/DFF regulator of apoptotic nuclease is nuclear
    • Samejima, K. & Earnshaw, W. C. 1998 ICAD/DFF regulator of apoptotic nuclease is nuclear. Exp. Cell Res. 243, 453-459.
    • (1998) Exp. Cell Res. , vol.243 , pp. 453-459
    • Samejima, K.1    Earnshaw, W.C.2
  • 35
    • 15644384377 scopus 로고    scopus 로고
    • Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution
    • Samejima, K. (and 10 others) 1998 Transition from caspase-dependent to caspase-independent mechanisms at the onset of apoptotic execution. J. Cell Biol. 143, 225-239.
    • (1998) J. Cell Biol. , vol.143 , pp. 225-239
    • Samejima, K.1
  • 36
    • 0028964628 scopus 로고
    • Isolation and partial characterization of a protease involved in Fas-induced apoptosis
    • Schlegel, J., Peters, I. & Orrenius, S. 1995 Isolation and partial characterization of a protease involved in Fas-induced apoptosis. FEBS Lett. 364, 139-142.
    • (1995) FEBS Lett. , vol.364 , pp. 139-142
    • Schlegel, J.1    Peters, I.2    Orrenius, S.3
  • 37
    • 0027994239 scopus 로고
    • Cell nucleus and DNA fragmentation are not required for apoptosis
    • Schulze-Osthoff, K., Walczak, H., Dröge, W. & Krammer, P. H. 1994 Cell nucleus and DNA fragmentation are not required for apoptosis. J. Cell Biol. 127, 15-20.
    • (1994) J. Cell Biol. , vol.127 , pp. 15-20
    • Schulze-Osthoff, K.1    Walczak, H.2    Dröge, W.3    Krammer, P.H.4
  • 38
    • 0027403207 scopus 로고
    • Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors
    • Solary, E., Bertrand, R., Kohn, K. W. & Pommier, Y. 1993 Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors. Blood 81, 1359-1368.
    • (1993) Blood , vol.81 , pp. 1359-1368
    • Solary, E.1    Bertrand, R.2    Kohn, K.W.3    Pommier, Y.4
  • 39
    • 0029758833 scopus 로고    scopus 로고
    • Cleavage of lamin A by MCH2α but not CPP32: Multiple ICE-related proteases with distinct substrate recognition properties are active in apoptosis
    • Takahashi, A. (and 10 others) 1996a Cleavage of lamin A by MCH2α but not CPP32: Multiple ICE-related proteases with distinct substrate recognition properties are active in apoptosis. Proc. Natl Acad. Sci. USA 93, 8395-8400.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 8395-8400
    • Takahashi, A.1
  • 40
    • 12644256886 scopus 로고    scopus 로고
    • CrmA/SPI-2 inhibition of an endogenous ICE-related protease responsible for lamin A cleavage and apoptotic nuclear fragmentation
    • Takahashi, A., Musy, P.-Y., Martins, L. M., Poirier, G. G., Turner, P. C., Moyer, R. W. & Earnshaw, W. C. 1996b CrmA/SPI-2 inhibition of an endogenous ICE-related protease responsible for lamin A cleavage and apoptotic nuclear fragmentation. J. Biol. Chem. 271, 32 487-32 490.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32487-32490
    • Takahashi, A.1    Musy, P.-Y.2    Martins, L.M.3    Poirier, G.G.4    Turner, P.C.5    Moyer, R.W.6    Earnshaw, W.C.7
  • 41
    • 0026672306 scopus 로고
    • Activation driven T cell death. H. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death
    • Ucker, D. S., Meyers, J. & Obermiller, P. S. 1992 Activation driven T cell death. H. Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death. J. Immunol. 149, 1583-1592.
    • (1992) J. Immunol. , vol.149 , pp. 1583-1592
    • Ucker, D.S.1    Meyers, J.2    Obermiller, P.S.3
  • 43
    • 15644364847 scopus 로고
    • Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
    • Woo, M. (and 13 others) 1992 Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 12, 806-819.
    • (1992) Genes Dev. , vol.12 , pp. 806-819
    • Woo, M.1
  • 44
    • 0025666621 scopus 로고
    • Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II
    • Wood, E. R. & Earnshaw, W. C. 1990 Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II. J. Cell Biol. 111, 2839-2850.
    • (1990) J. Cell Biol. , vol.111 , pp. 2839-2850
    • Wood, E.R.1    Earnshaw, W.C.2
  • 45
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie, A. H. 1980 Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 46
  • 47
    • 0029906828 scopus 로고    scopus 로고
    • BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases
    • Xiang, J., Chao, D. T. & Korsmeyer, S. J. 1996 BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases. Proc. Natl Acad. Sci. USA 93, 14 559-14 563.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 48
    • 0025255636 scopus 로고
    • The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
    • Yuan, J. Y. & Horvitz, H. R. 1990 The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev. Biol. 138, 33-41.
    • (1990) Dev. Biol. , vol.138 , pp. 33-41
    • Yuan, J.Y.1    Horvitz, H.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.