Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase

Biochemistry

Volumn 35, Issue 51, 1996, Pages 16621-16629

  Abdus Sattar, A K M ^a   Lin, Tsung Chung ^a   Jones, Christopher ^a   Konigsberg, William H ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACTERIOPHAGE; CRYSTAL STRUCTURE; DNA REPLICATION; ENZYME KINETICS; ENZYME LOCALIZATION; ESCHERICHIA COLI; GENE REARRANGEMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; BACTERIOPHAGE T4; BASE SEQUENCE; CONSERVED SEQUENCE; DNA POLYMERASE I; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; EXONUCLEASES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; ESCHERICHIA COLI; EUKARYOTA; FELIS CATUS;

EID: 0001653511     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961552q     Document Type: Article

References (42)

1. Beese, L. S., & Steitz, T. A. (1989) in Nucleic Acids & Molecular Biology (Eckstein, F., & Lilley, D. M. J., Eds.) Vol. 3, pp 28-43, Springer-Verlag, Berlin.
2. Beese, L., & Steitz, T. A. (1991) EMBO J. 10, 25-33.
3. Blanco, L., Bernad, A., Blasco, M. A., & Salas, M. (1991) Gene 100, 27-38.
4. Blanco, L., Bernad, A., & Salas, M. (1992) Gene 112, 139-144.
5. Blasco, M. A., Lazaro, J. M., Bernad, A., Blanco, L., & Salas, M. (1992) J. Biol. Chem. 267, 19427-19434.
6. Blasco, M. A., Lazaro, J. M., Blanco, L., & Salas, M. (1993a) J. Biol. Chem. 268, 16763-16770.
7. Blasco, M. A., Lazaro, J. M., Blanco, L., & Salas, M. (1993b) J. Biol. Chem. 268, 24106-24113.
8. Blasco, M. A., Mendez, J., Lazaro, J. M., Blanco, L., & Salas, M. (1995) J. Biol. Chem. 270, 2735-2740.
9. Brenowitz, S., Kwack, S., Goodman, M. F., O'Donnell, M., & Echols, H. (1991) J. Biol. Chem. 266, 7888-7892.
10. Carroll, S. S., & Benkovic, S. J. (1990) Chem. Rev. 90, 1291-1307.
11. Catalano, C. E., Allen, D. J., & Benkovic, S. J. (1990) Biochemistry 29, 3612-3621.
12. Copeland, W. C., & Wang, T. S.-F. (1993) J. Biol. Chem. 268, 11028-11040.
13. Copeland, W. C., Lam, N. K., & Wang, T. S.-F. (1993) J. Biol. Chem. 268, 11041-11049.
14. Cowart, M., Gibson, K. J., Allen, D. J., & Benkovic, S. J. (1989) Biochemistry 28, 1975-1983.
15. Derbyshire, V., Grindly, N. D. F., & Joyce, C. M., (1991) EMBO J. 10, 17-24.
16. Dong, Q., & Wang, T. S. F. (1995) J. Biol. Chem. 270, 21536-21570.
17. Dong, Q., Copeland, W. C., & Wang, T. S. F. (1993a) J. Biol. Chem. 268, 24163-24174.
18. Dong, Q., Copeland, W. C., & Wang, T. S. F. (1993b) J. Biol. Chem. 265, 24175-24182.
19. Freemont, P. S., Ollis, D. L., Steitz, T. A., & Joyce, C. M. (1986) Proteins 1, 66-73.
20. Frey, M. W., Nossal, N. G., Capson, T. L., & Benkovic, S. J. (1993) Proc. Natl. Acad Sci. U.S.A. 90, 2579-2583.
21. Goodman, M. F., Creighton, S., Bloom, L. B., & Petruska, J. (1993) CRC Crit. Rev. Biochem. Mol. Biol. 28, 83-126.
22. Gopalakrishnan, V., & Benkovic, S. J. (1994) J. Biol. Chem. 269, 21123-21126.
23. Ito, J., & Braithwaite, D. K. (1991) Nucleic Acids Res. 19, 4045-4057.
24. Joyce, C. M., & Steitz, T. A. (1994) Annu. Rev. Biochem. 63, 777-822.
25. Kunkel, T. A. (1988) Cell 53, 837-840.
26. Kunkel, T. A., & Loeb, A. (1984) J. Biol. Chem. 259, 1539-1545.
27. Kunkel, T. A., Roberts, J. D., & Zakour, R. A. (1987) Methods Enzymol. 154, 367-382.
28. Lin, T. C., Karam, G., & Konigsberg, W. H. (1994) J. Biol. Chem. 269, 19286-19294.
29. Maki, H., & Kornberg, A. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 4389-4392.
30. Morrison, A., Bill, J. B., Kunkel, T. A., & Sugino, A., (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 9473-9477.
31. Nossal, N. G. (1992) FASEB J. 3, 871-878.
32. Nossal, N., & Alberts, B. (1983) in Bacteriaphage T4 (Mathews, C. K., Kutter, E. M., Mosig, G., & Berget, P. B., Eds.) pp 71-81, American Society for Microbiology, Washington, DC.
33. Reddy, M. K., Weitzel, S. E., & von Hippel, P. H. (1992) J. Biol. Chem. 267, 14157-14166.
34. Reha-Krantz, L. J., & Nonay, R. L. (1993) J. Biol. Chem. 268, 27100-27108.
35. Sambrook, J., Fritch, E. F., & Maniatis, T. (1989) Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
36. Scheuermann, R. H., & Echols, H. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 7747-7751.
37. Spacciapoli, P., & Nossal, N. G. (1994) J. Biol. Chem. 269, 438-446.
38. Spicer, E. K., Rush, J., Fang, C., Reha-Krantz, L. J., Karam, J., & Konigsberg, W. H. (1988) J. Biol. Chem. 263, 7478-7486.
39. Wang, C. C., Yeh, L. S., & Karam, J. D. (1995) J. Biol. Chem. 270, 26558-26564.
40. Wang, J., Yu, P., Lin, T. C., Konigsberg, W. H., & Steitz, T. A. (1996) Biochemistry 35, 8110-8119.
41. Young, M. C., Reddy, M. K., & von Hippel, P. H. (1992) Biochemistry 31, 8678-8690.
42. Zhu, W., Leavitt, M. C., Jung, G., & Ito, J. (1994) Biochim. Biophys. Acta 1219, 260-266.