Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells

Blood

Volumn 90, Issue 3, 1997, Pages 1241-1245

  Longo, Giuseppe S A ^a   Gorlick, Richard ^a   Tong, William P ^a   Ercikan, Emine ^a   Bertino, Joseph R ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 [[(1,2 DIHYDRO 3 METHYL 1 OXOBENZO[F]QUINAZOLIN 9 YL)METHYL]AMINO] 1 OXO 2 ISOINDOLINYL]GLUTARIC ACID; FOLIC ACID ANTAGONIST; FOLYLPOLYGLUTAMATE SYNTHASE; METHOTREXATE; RALTITREXED; THYMIDYLATE SYNTHASE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; BINDING AFFINITY; BLAST CELL; BLAST CELL CRISIS; CYTOTOXICITY; DRUG ACCUMULATION; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL;

EID: 0030831351     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.3.1241     Document Type: Article

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