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Volumn 160, Issue 2, 1999, Pages 217-223

Antileukotriene agents in asthma: The dart that kills the elephant?

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CORTICOSTEROID; LEUKOTRIENE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; MONTELUKAST; PRANLUKAST; ZAFIRLUKAST; ZILEUTON;

EID: 0033604892     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (13)

References (60)
  • 1
    • 0023567409 scopus 로고
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma
    • 1. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987;136:225-44.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 225-244
  • 3
    • 0027535474 scopus 로고
    • Airway mucosal inflammation even in patients with newly diagnosed asthma
    • 3. Laitinen LA, Laitinen A, Haahtela T. Airway mucosal inflammation even in patients with newly diagnosed asthma. Am Rev Respir Dis 1993;147:697-704.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 697-704
    • Laitinen, L.A.1    Laitinen, A.2    Haahtela, T.3
  • 4
    • 0029961755 scopus 로고    scopus 로고
    • Canadian asthma consensus conference: Summary of recommendations
    • 4. Ernst P, FitzGerald JM, Spier S. Canadian Asthma Consensus Conference: summary of recommendations. Can Respir J 1996;3:89-100.
    • (1996) Can Respir J , vol.3 , pp. 89-100
    • Ernst, P.1    FitzGerald, J.M.2    Spier, S.3
  • 6
    • 0027177966 scopus 로고
    • Practical issues in asthma management: Correct use of inhalation devices
    • 6. Cockcroft DW. Practical issues in asthma management: correct use of inhalation devices. Ann Allergy 1993;71:83-4.
    • (1993) Ann Allergy , vol.71 , pp. 83-84
    • Cockcroft, D.W.1
  • 7
    • 0025096776 scopus 로고
    • Complications of topical steroid therapy for asthma
    • 7. Toogood JH. Complications of topical steroid therapy for asthma. Am Rev Respir Dis 1990;141(2 pt 2):S89-96.
    • (1990) Am Rev Respir Dis , vol.141 , Issue.2 PART 2
    • Toogood, J.H.1
  • 8
    • 0030859363 scopus 로고    scopus 로고
    • Use of inhaled corticosteroids and the risk of cataracts
    • 8. Cumming RG, Mitchell P, Leeder SR. Use of inhaled corticosteroids and the risk of cataracts. N Engl J Med 1997;337:8-14.
    • (1997) N Engl J Med , vol.337 , pp. 8-14
    • Cumming, R.G.1    Mitchell, P.2    Leeder, S.R.3
  • 9
    • 0027945466 scopus 로고
    • Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
    • 9. Chen XS, Sheller JR, Johnson EN, Funk CD. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature 1994;372:179-82.
    • (1994) Nature , vol.372 , pp. 179-182
    • Chen, X.S.1    Sheller, J.R.2    Johnson, E.N.3    Funk, C.D.4
  • 11
    • 84980124399 scopus 로고
    • The liberation of a slow-reacting smooth muscle-stimulating substance in anaphylaxis
    • 11. Kellaway CH, Trethewie ER. The liberation of a slow-reacting smooth muscle-stimulating substance in anaphylaxis. Q J Exp Physiol Cogn Med Sci 1940;30:121-45.
    • (1940) Q J Exp Physiol Cogn Med Sci , vol.30 , pp. 121-145
    • Kellaway, C.H.1    Trethewie, E.R.2
  • 12
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
    • 12. Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 1983;220:568-75.
    • (1983) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 16
    • 0023589276 scopus 로고
    • Leukotrienes and airway responses
    • 16. Drazen JM, Austen KF. Leukotrienes and airway responses. Am Rev Respir Dis 1987;136:985-98.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 985-998
    • Drazen, J.M.1    Austen, K.F.2
  • 17
    • 0029152856 scopus 로고
    • Cysteinyl leukotrienes in asthma: Old mediators up to new tricks
    • 17. Hay DW, Torphy TJ, Undem BJ. Cysteinyl leukotrienes in asthma: old mediators up to new tricks. Trends Pharmacol Sci 1995;16:304-9.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 304-309
    • Hay, D.W.1    Torphy, T.J.2    Undem, B.J.3
  • 19
    • 4243867643 scopus 로고    scopus 로고
    • Pranlukast (SB205312, ONO 1078), a leukotriene receptor antagonist, attenuates allergen-induced early and late phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects
    • 19. Hamilton AL, Faiferman I, Stober P, Watson PM, O'Byrne PM. Pranlukast (SB205312, ONO 1078), a leukotriene receptor antagonist, attenuates allergen-induced early and late phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects [abstract]. Eur Respir J 1997;10(Suppl 25):419s.
    • (1997) Eur Respir J , vol.10 , Issue.SUPPL. 25
    • Hamilton, A.L.1    Faiferman, I.2    Stober, P.3    Watson, P.M.4    O'Byrne, P.M.5
  • 20
    • 0026524337 scopus 로고
    • Effect of the oral leukotriene antagonist, ICI 204,219, on antigen-induced bronchoconstriction in subjects with asthma
    • 20. Findlay SR, Barden JM, Easley CB, Glass M. Effect of the oral leukotriene antagonist, ICI 204,219, on antigen-induced bronchoconstriction in subjects with asthma. J Allergy Clin Immunol 1992;89:1040-5.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 1040-1045
    • Findlay, S.R.1    Barden, J.M.2    Easley, C.B.3    Glass, M.4
  • 21
    • 0026078163 scopus 로고
    • Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients
    • 21. Hui KP, Taylor IK, Taylor GW, Rubin P, Kesterson J, Barnes NC, et al. Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients. Thorax 1991;46:184-9.
    • (1991) Thorax , vol.46 , pp. 184-189
    • Hui, K.P.1    Taylor, I.K.2    Taylor, G.W.3    Rubin, P.4    Kesterson, J.5    Barnes, N.C.6
  • 22
    • 0030033328 scopus 로고    scopus 로고
    • A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings
    • 22. Kane GC, Pollice M, Kim CJ, Cohn J, Dworski RT, Murray JJ. A controlled trial of the effect of the 5-lipoxygenase inhibitor, zileuton, on lung inflammation produced by segmental antigen challenge in human beings. J Allergy Clin Immmunol 1996;97:646-54.
    • (1996) J Allergy Clin Immmunol , vol.97 , pp. 646-654
    • Kane, G.C.1    Pollice, M.2    Kim, C.J.3    Cohn, J.4    Dworski, R.T.5    Murray, J.J.6
  • 23
    • 0027469691 scopus 로고
    • Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma
    • 23. Fujimura M, Sakamoto S, Kamio Y, Matsuda T. Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma. Respir Med 1993;87:133-8.
    • (1993) Respir Med , vol.87 , pp. 133-138
    • Fujimura, M.1    Sakamoto, S.2    Kamio, Y.3    Matsuda, T.4
  • 24
    • 0026066945 scopus 로고
    • Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and, airway hyperreactivity in atopic subjects
    • 24. Taylor IK, O'Shaughnessy KM, Fuller RW, Dollery CT. Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and, airway hyperreactivity in atopic subjects. Lancet 1991;337:690-4.
    • (1991) Lancet , vol.337 , pp. 690-694
    • Taylor, I.K.1    O'Shaughnessy, K.M.2    Fuller, R.W.3    Dollery, C.T.4
  • 26
    • 0001622954 scopus 로고    scopus 로고
    • Montelukast, leukotriene receptor antagonist, inhibits exercise induced bronchoconstriction in 6-14 year old children
    • 26. Kemp JP, Dockhorn RJ, Shapiro GG, Nguyen HH, Guerrero DA, Reiss TF. Montelukast, leukotriene receptor antagonist, inhibits exercise induced bronchoconstriction in 6-14 year old children [abstract]. J Allergy Clin Immunol 1997;99:S321.
    • (1997) J Allergy Clin Immunol , vol.99
    • Kemp, J.P.1    Dockhorn, R.J.2    Shapiro, G.G.3    Nguyen, H.H.4    Guerrero, D.A.5    Reiss, T.F.6
  • 27
    • 0001487921 scopus 로고    scopus 로고
    • Montelukast (MK-0476) inhibits exercise-induced bronchoconstriction (EIB) over 12 weeks without causing tolerance
    • 27. Leff JA, Bronsky EA, Kemp J, Pearlman DS, Hendeles L, Busse WW, et al. Montelukast (MK-0476) inhibits exercise-induced bronchoconstriction (EIB) over 12 weeks without causing tolerance [abstract]. Am J Respir Crit Care Med 1997;155:A977.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Leff, J.A.1    Bronsky, E.A.2    Kemp, J.3    Pearlman, D.S.4    Hendeles, L.5    Busse, W.W.6
  • 32
    • 0025685169 scopus 로고
    • Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor
    • 32. Knapp HR. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. N Engl J Med 1990;323:1745-8.
    • (1990) N Engl J Med , vol.323 , pp. 1745-1748
    • Knapp, H.R.1
  • 35
    • 0027762572 scopus 로고
    • The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin
    • 35. Israel E, Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Shapiro J, et al. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis 1993;148:1447-51.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1447-1451
    • Israel, E.1    Fischer, A.R.2    Rosenberg, Ma.3    Lilly, C.M.4    Callery, J.C.5    Shapiro, J.6
  • 36
    • 0032522735 scopus 로고    scopus 로고
    • Montelukast for chronic asthma in 6- to 14-year-old children: A randomized, double blind trial
    • Pediatric Montelukast Study Group
    • 36. Knorr B, Matz J, Bernstein JA, Nguyen H, Seidenberg BC, Reiss TF, et al. Montelukast for chronic asthma in 6- to 14-year-old children: a randomized, double blind trial. Pediatric Montelukast Study Group. JAMA 1998;279:1181-6.
    • (1998) JAMA , vol.279 , pp. 1181-1186
    • Knorr, B.1    Matz, J.2    Bernstein, J.A.3    Nguyen, H.4    Seidenberg, B.C.5    Reiss, T.F.6
  • 38
    • 0000869607 scopus 로고    scopus 로고
    • The effect of leukotriene antagonist pranlukast on moderate and severe persistent asthma continues more than one year
    • 38. Kohrogi H, Iwagoe H, Fujii K, Fukuda K, Kawano O, Hamamoto J, et al. The effect of leukotriene antagonist pranlukast on moderate and severe persistent asthma continues more than one year [abstract]. Am J Respir Crit Care Med 1997;155:A662.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Kohrogi, H.1    Iwagoe, H.2    Fujii, K.3    Fukuda, K.4    Kawano, O.5    Hamamoto, J.6
  • 39
    • 0028103864 scopus 로고
    • 4 receptor antagonist, in subjects with bronchial asthma
    • ACCOLATE Asthma Trialists Group
    • 4 receptor antagonist, in subjects with bronchial asthma. ACCOLATE Asthma Trialists Group. Am J Respir Crit Care Med 1994;150:618-23.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 618-623
    • Spector, S.L.1    Smith, L.J.2    Glass, M.3
  • 40
    • 0027369276 scopus 로고
    • The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma
    • 40. Israel E, Rubin P, Kemp JP, Grossman J, Pierson W, Siegel SC, et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med 1993;119:1059-66.
    • (1993) Ann Intern Med , vol.119 , pp. 1059-1066
    • Israel, E.1    Rubin, P.2    Kemp, J.P.3    Grossman, J.4    Pierson, W.5    Siegel, S.C.6
  • 41
    • 0001487922 scopus 로고    scopus 로고
    • Effect of montelukast (MK-0476) on airway eosinophilic inflammation in mildly uncontrolled asthma: A randomized placebo-controlled trial
    • 41. Leff JA, Pizzichini E, Efthimiadis A, Boulet LP, Wei LX, Weinland DE, et al. Effect of montelukast (MK-0476) on airway eosinophilic inflammation in mildly uncontrolled asthma: a randomized placebo-controlled trial [abstract]. Am J Respir Crit Care Med 1997;155:A977.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Leff, J.A.1    Pizzichini, E.2    Efthimiadis, A.3    Boulet, L.P.4    Wei, L.X.5    Weinland, D.E.6
  • 43
  • 47
    • 0001487922 scopus 로고    scopus 로고
    • Montelukast (MK-0476) allows tapering of inhaled corticosteroids (ICS) in asthmatic patients while maintaining clinical stability
    • 47. Leff JA, Israel E, Noonan MJ, Finn AF, Godard P, Lofdahl CG, et al. Montelukast (MK-0476) allows tapering of inhaled corticosteroids (ICS) in asthmatic patients while maintaining clinical stability [abstract]. Am J Respir Crit Care Med 1997;155:A976.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Leff, J.A.1    Israel, E.2    Noonan, M.J.3    Finn, A.F.4    Godard, P.5    Lofdahl, C.G.6
  • 48
    • 0030903255 scopus 로고    scopus 로고
    • Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid
    • The Tokyo Joshi-Idai Asthma Research Group
    • 48. Tamaoki J, Kondo M, Sakai N, Nakata J, Takemura H, Nagai A, et al. Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid. The Tokyo Joshi-Idai Asthma Research Group. Am J Respir Crit Care Med 1997;155:1235-40.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1235-1240
    • Tamaoki, J.1    Kondo, M.2    Sakai, N.3    Nakata, J.4    Takemura, H.5    Nagai, A.6
  • 50
    • 0000664311 scopus 로고
    • Effects of 'accolate' (zafirlukast; 20 mg bd) in permitting reduced therapy with inhaled steroids: A multicentre trial in patients with doses of inhaled steroid optimised between 800 and 2000 mcg per day
    • 50. Laitinen LA, Zetterstroem O, Holgate ST, Binks SM, Whitney JG. Effects of 'Accolate' (zafirlukast; 20 mg bd) in permitting reduced therapy with inhaled steroids: a multicentre trial in patients with doses of inhaled steroid optimised between 800 and 2000 mcg per day [abstract]. Allergy 1995;50(Suppl 26):320.
    • (1995) Allergy , vol.50 , Issue.SUPPL. 26 , pp. 320
    • Laitinen, L.A.1    Zetterstroem, O.2    Holgate, S.T.3    Binks, S.M.4    Whitney, J.G.5
  • 51
    • 0000733047 scopus 로고    scopus 로고
    • Pranlukast (Ultair) improves FEV in patients with asthma: Results of a 12 week multicenter study vs. nedocromil
    • 51. Sahn SA, Galant S, Murray J, Bronsky E, Spector S, Faiferman I, et al. Pranlukast (Ultair) improves FEV in patients with asthma: results of a 12 week multicenter study vs. nedocromil [abstract]. Am J Respir Crit Care Med 1997;155:A665.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Sahn, S.A.1    Galant, S.2    Murray, J.3    Bronsky, E.4    Spector, S.5    Faiferman, I.6
  • 52
    • 0000733048 scopus 로고    scopus 로고
    • Two weeks treatment with zafirlukast (accolate), sodium cromoglycate or placebo on exercise-induced bronchoconstriction in asthmatic adolescents
    • 52. Hofstra WB, Sterk PJ, Neijens HJ, van der Weij AM, van Zoest JGCM, Duiverman EJ. Two weeks treatment with zafirlukast (Accolate), sodium cromoglycate or placebo on exercise-induced bronchoconstriction in asthmatic adolescents [abstract]. Am J Respir Crit Care Med 1997;155:A665.
    • (1997) Am J Respir Crit Care Med , vol.155
    • Hofstra, W.B.1    Sterk, P.J.2    Neijens, H.J.3    Van Der Weij, A.M.4    Van Zoest, J.G.C.M.5    Duiverman, E.J.6
  • 53
    • 0013562459 scopus 로고
    • The comparative effects of zileuton, a 5-lipoxygenase inhibitor vs. theophylline in patients with moderate asthma: Results from a 13 week, multicenter trial
    • 53. Schwartz HJ, Petty T, Reed R, Dubé LM, Swanson LJ. The comparative effects of zileuton, a 5-lipoxygenase inhibitor vs. theophylline in patients with moderate asthma: results from a 13 week, multicenter trial [abstract] Am J Respir Crit Care Med 1995;151:A376.
    • (1995) Am J Respir Crit Care Med , vol.151
    • Schwartz, H.J.1    Petty, T.2    Reed, R.3    Dubé, L.M.4    Swanson, L.J.5
  • 55
    • 0031913201 scopus 로고    scopus 로고
    • Perception of the role and potential side effects of inhaled corticosteroids among asthmatic patients
    • 55. Boulet LP. Perception of the role and potential side effects of inhaled corticosteroids among asthmatic patients. Chest 1998;113:587-92.
    • (1998) Chest , vol.113 , pp. 587-592
    • Boulet, L.P.1
  • 56
    • 0031044230 scopus 로고    scopus 로고
    • Zileuton for asthma
    • 56. Zileuton for asthma. Med Lett Drugs Ther 1997;39:18-9.
    • (1997) Med Lett Drugs Ther , vol.39 , pp. 18-19
  • 57
    • 0030463791 scopus 로고    scopus 로고
    • Zafirlukast for asthma
    • 57. Zafirlukast for asthma. Med Lett Drugs Ther 1996;38:111-2.
    • (1996) Med Lett Drugs Ther , vol.38 , pp. 111-112
  • 58
    • 6844250776 scopus 로고    scopus 로고
    • Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast
    • 58. Wechsler ME, Garpestad E, Flier SR, Kocher O, Weiland DA, Polito AJ, et al. Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast. JAMA 1998;279:455-7.
    • (1998) JAMA , vol.279 , pp. 455-457
    • Wechsler, M.E.1    Garpestad, E.2    Flier, S.R.3    Kocher, O.4    Weiland, D.A.5    Polito, A.J.6


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