Relationship between productive HIV-1 infection of macrophages and CCR5 utilization

Virology

Volumn 264, Issue 2, 1999, Pages 278-288

  Hung, Chia Suei ^a   Pontow, Suzanne ^a   Ratner, Lee ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BINDING AFFINITY; CELL IMMORTALIZATION; CHIMERA; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACROPHAGE FUNCTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0033604647     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.0013     Document Type: Article

References (49)

1. Alkhatib G., Ahuja S. S., Light D., Mummidi S., Berger E. A., Ahuja S. K. CC chemokine receptor 5-mediated signaling and HIV-1 co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion. J. Biol. Chem. 272:1997;19771-19776.
2. Alkhatib G., Combadiere C., Broder C. C., Feng Y., Kennedy P. E., Murphy P. M., Berger E. A. CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science. 272:1996;1955-1958.
3. Benkirane M., Jin D. Y., Chun R. F., Koup R. A., Jeang K. T. Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32. J. Biol. Chem. 272:1997;30603-30606.
4. Berson J. F., Doms R. W. Structure-function studies of the HIV-1 coreceptors. Sem. Immunol. 10:1998;237-248.
5. Bieniasz P. D., Fridell R. A., Aramori I., Ferguson S. S. G., Caron M. G., Cullen B. R. HIV-1 induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. EMBO J. 16:1997;2599-2609.
6. Blauvelt A., Katz S. I. The skin as target, vector, and effector organ in human immunodeficiency virus disease. J. Inves. Dermatol. 105:1995;122S-126S.
7. Cheng-Mayer C., Liu R., Landau N. R., Stamatatos L. Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor. J. Virol. 71:1997;1657-1661.
8. Chesebro B., Wehrly K., Nishio J., Perryman S. Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell-tropic isolates: Definition of critical amino acids involved in cell tropism. J. Virol. 66:1992;6547-6554.
9. Choe H., Farzan M., Sun Y., Sullivan N., Rollins B., Ponath P. D., Wu L., Mackay C. R., LaRosa G., Newman W., Gerard N., Gerard C., Sodroski J. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 85:1996;1135-1148.
10. Choe H. R., Sodroski J. Adaptation of human immunodeficiency virus type 1 to cells expressing a binding-deficient CD4 mutant (lysine 46 to aspartic acid). J. Virol. 69:1995;2801-2810.
11. Cocchi F., DeVico A. L., Garzino-Demo A., Cara A., Gallo R. C., Lusso P. The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection. Nat. Med. 2:1996;1244-1247.
12. Crowe S. M. Role of macrophages in the pathogenesis of human immunodeficiency virus (HIV) infection. Aust. N. Z. J. Med. 25:1995;777-783.
13. Deng H., Liu R., Ellmeier W., Choe S., Unutmaz D., Burkhart M., Di Marzio P., Marmon S., Sutton R. E., Hill C. M., Davis C. B., Peiper S. C., Schall T. J., Littman D. R., Landau N. R. Identification of a major co-receptor for primary isolates of HIV-1. Nature. 381:1996;661-666.
14. Dittmar M. T., McKnight A., Simmons G., Clapham P. R., Weiss R. A., Simmonds P. HIV-1 tropism and co-receptor use [letter]. Nature. 385:1997;495-496.
15. Doms R. W., Moore J. P. HIV-1 coreceptor use: A molecular window into viral tropism. Myers G., Korber B. T., Foley B. T., Jeang K.-T., Mellors J. W., Wain-Hobson S. Human Retroviruses and AIDS 1997, A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences. 1997;III.1-12 Los Alamos National LaboratoryTheoretical Biol. and Biophysics Group, Los Alamos.
16. Dragic T., Litwin V., Allaway G. P., Martin S. R., Huang Y., Nagashima K. A., Cayanan C., Maddon P. J., Koup R. A., Moore J. P., Paxton W. A. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature. 381:1996;667-673.
17. Farzan M., Mirzabekov T., Kolchinsky P., Wyatt R., Cayabyab M., Gerard N. P., Gerard C., Sodroski J., Choe H. Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry. Cell. 96:1999;667-676.
18. Gartner S., Markovits P., Markovitz D., Kaplan M., Gallo R., Popovic M. The role of mononuclear phagocytes in HTLV-III/LAV infection. Science. 233:1986;215-219.
19. Henkel T., Westervelt P., Ratner L. HIV-1 V3 envelope sequences required for macrophage infection. AIDS. 9:1995;399-401.
20. Hesselgesser J., Liang M., Hoxie J., Greenberg M., Brass L. F., Orsini M. J., Taub D., Horuk R. Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: Ligand binding, biological activity, and HIV-1 infectivity. J. Immunol. 160:1998;877-883.
21. Hill C. M., Kwon D., Jones M., Davis C. B., Marmon S., Daugherty B. L., DeMartino J. A., Springer M. S., Unutmaz D., Littman D. R. The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins. Virol. 248:1998;357-371.
22. Hung C.-S., Vander Heyden N., Ratner L. Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization. J. Virol. 73:1999;8216-8226.
23. Hwang S. S., Boyle T. J., Lyerly H. K., Cullen B. R. Identification of envelope V3 loop as the major determinant of CD4 neutralization sensitivity of HIV-1. Science. 257:1992;535-537.
24. Kato K., Sato H., Takebe Y. Role of naturally occurring basic amino acid substitutions in the human immunodeficiency virus type 1 subtype E envelope V3 loop on viral coreceptor usage and cell tropism. J. Virol. 73:1999;5520-5526.
25. Kimpton J., Emerman M. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene. J. Virol. 66:1992;2232-2239.
26. Koyanagi Y., Miles S., Mitsuyasu R. T., Merrill J. E., Vinters H. V., Chen I. S. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science. 236:1987;819-822.
27. Kozak S. L., Platt E. J., Madani N., Ferro F. E. Jr., Peden K., Kabat D. CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1. J. Virol. 71:1997;873-882.
28. Kwong P. D., Wyatt R., Robinson J., Sweet R. W., Sodroski J., Hendrickson W. A. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature. 393:1998;648-659.
29. Lee B., Sharron M., Blainpai C., Doranz B., Vakili J., Seto P., Parmentier M., Chang C.-N., Tsang M., Doms R. W. 6th Conference on Retroviruses and Opportunistic Infections, Chicago, IL USA. 1999.
30. Levy J. A. Pathogenesis of human immunodeficiency virus infection. Microbiol. Rev. 57:1993;183-289.
31. Mosier D., Sieburg H. Macrophage-tropic HIV: Critical for AIDS pathogenesis. Immunol. Today. 15:1994;332-339.
32. Naif H. M., Li S., Alali M., Sloane A., Wu L., Kelly M., Lynch G., Lloyd A., Cunningham A. L. CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infection. J. Virol. 72:1998;830-836.
33. Nussbaum O., Broder C. C., Berger E. A. Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation. J. Virol. 68:1994;5411-5422.
34. Platt E. J., Wehrly K., Kuhmann S. E., Chesebro B., Kabat D. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophage isolates of human immunodeficiency virus type 1. J. Virol. 72:1998;2855-2864.
35. Rana S., Besson G., Cook D. G., Rucker J., Smyth R. J., Yi Y., Turner J. D., Guo H. H., Du J. G., Peiper S. C., Lavi E., Samson M., Libert F., Liesnard C., Vassart G., Doms R. W., Parmentier M., Collman R. G. Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: Resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation. J. Virol. 71:1997;3219-3227.
36. Rizzuto C. D., Wyatt R., Hernández-Ramos N., Sun Y., Kwong P. D., Hendrickson W. A., Sodroski J. A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding. Science. 280:1998;1949-1953.
37. Ross T. M., Bieniaz P. D., Cullen B. R. Multiple residues contribute to the inability of murine CCR-5 to function as a coreceptor for macrophage-tropic human immunodeficiency virus type 1 isolates. J. Virol. 72:1998;1918-1924.
38. Schmidtmayerova H., Alfano M., Nuovo G., Bukrinsky M. Human immunodeficiency virus type 1 T-lymphotropic strains enter macrophages via a CD4- and CXCR4-mediated pathway: Replication is restricted at a postentry level. J. Virol. 72:1998;4633-4642.
39. Schuitemaker H. Macrophage-tropic HIV-1 variants: Initiators of infection and AIDS pathogenesis. J. Leukocyte Biol. 56:1994;218-224.
40. Simmons G., Reeves J. D., McKnight A., Dejucq N., Hibbitts S., Power C. A., Aarons E., Schols D., De Clercq E., Proudfoot A. E., Clapham P. R. CXCR4 as a functional coreceptor for human immunodeficiency virus type 1 infection of primary macrophages. J. Virol. 72:1998;8453-8457.
41. Stanley S. K., Fauci A. S. Detection assays for HIV proteins. Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. Current Protocols in Molecular Biology. 1993;12.5.1-15 John Wiley & Sons, New York.
42. Tuttle D. L., Harrison J. K., Anders C., Sleasman J. W., Goodenow M. M. Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1. J. Virol. 72:1998;4962-4969.
43. Verani A., Pesenti E., Polo S., Tresoldi E., Scarlatti G., Lusso P., Siccardi A. G., Vercelli D. CXCR4 is a functional coreceptor for infection of human macrophages by CXCR4-dependent primary HIV-1 isolates. J. Immunol. 161:1998;2084-2088.
44. Westervelt P., Gendelman H. E., Ratner L. Identification of a determinant within the HIV-1 surface envelope glycoprotein critical for productive infection of cultured primary monocytes. Proc. Natl. Acad. Sci.USA. 88:1991;3097-3101.
45. Wrischnik L. A., Higuchi R. G., Stoneking M., Erlich H. A., Arnheim N., Wilson A. C. Length mutations in human mitochondrial DNA: Direct sequencing of enzymatically amplified DNA. Nucleic Acids Res. 15:1987;529-542.
46. Wu L., LaRosa G., Kassam N., Gordon C. J., Heath H., Ruffing N., Chen H., Humblias J., Samson M., Parmentier M., Moore J. P., Mackay C. R. Interaction of chemokine receptor CCR5 with its ligands: Multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding. J. Exp. Med. 186:1997a;1373-1381.
47. Wu L., Paxton W. A., Kassam N., Ruffing N., Rottman J. B., Sullivan N., Choe H., Sodrosky J., Newman W., Koup R. A., Mackay C. R. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Ex. Med. 185:1997b;1681-1691.
48. Wyatt R., Kwong P. D., Desjardins E., Sweet R. W., Robinson J., Hendrickson W. A., Sodroski J. G. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature. 393:1998;705-711.
49. Yi Y., Rana S., Turner J. D., Gaddis N., Collman R. G. CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1. J. Virol. 72:1998;772-777.