Use of a peptide mimotope to guide the humanization of MRK-16, an anti- P-glycoprotein monoclonal antibody

Journal of Biological Chemistry

Volumn 274, Issue 39, 1999, Pages 27371-27378

  Tang, Ying ^a   Beuerlein, Greg ^a   Pecht, Gerlinde ^a   Chilton, Todd ^a   Huse, William D ^a   Watkins, Jeffry D ^a  

^a Ixsys Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT; GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; HYBRID PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; PEPTIDE LIBRARY;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; DNA TEMPLATE; GENETIC ENGINEERING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; TUMOR CELL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; COLORECTAL NEOPLASMS; EPITOPES; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; P-GLYCOPROTEIN; PEPTIDE LIBRARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TUMOR CELLS, CULTURED;

EID: 0033600861     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.39.27371     Document Type: Article

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