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Volumn 292, Issue 3, 1999, Pages 669-684

Recruiting Zn2+ to mediate potent, specific inhibition of serine proteases

Author keywords

pH dependence; Specificity; Structure based drug design; Zn2+ affinity; Zn2+ mediated serine protease inhibitors

Indexed keywords

BENZIMIDAZOLE; CARBONYL DERIVATIVE; NITROGEN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; TRYPSIN INHIBITOR; WATER; ZINC ION; BENZIMIDAZOLE DERIVATIVE; BIS(5 AMIDINO 2 BENZIMIDAZOLYL)METHANE; BIS(5-AMIDINO-2-BENZIMIDAZOLYL)METHANE; THROMBIN; TRYPSIN; ZINC;

EID: 0033600606     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3071     Document Type: Article
Times cited : (33)

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