Fatty acid induced insulin resistance in rat-1 fibroblasts overexpressing human insulin receptors: Impaired insulin-stimulated mitogen-activated protein kinase activity

Diabetologia

Volumn 40, Issue 8, 1997, Pages 894-901

  Usui, I ^a   Takata, Y ^a   Imamura, T ^a   Morioka, H ^a   Sasaoka, T ^a   Sawa, T ^a   Ishihara, H ^a   Ishiki, M ^a   Kobayashi, M ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Glucose transport; Insulin receptor; Insulin resistance; MAP kinase; Non esterified fatty acid

Indexed keywords

CYCLIC AMP; INSULIN; INSULIN RECEPTOR; PALMITIC ACID; PROTEIN KINASE; SATURATED FATTY ACID; SATURATED NONESTERIFIED FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FIBROBLAST; GLUCOSE TRANSPORT; INSULIN RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTIBODIES, MONOCLONAL; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; FIBROBLASTS; GLUCOSE TRANSPORTER TYPE 1; HUMANS; IMMUNE SERA; IMMUNOBLOTTING; INSULIN; INSULIN RESISTANCE; IODINE RADIOISOTOPES; MICE; MONOSACCHARIDE TRANSPORT PROTEINS; PALMITATES; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PRECIPITIN TESTS; PROTEIN-TYROSINE KINASES; PROTEINS; RABBITS; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 0030871965     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050765     Document Type: Article

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