Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 15, 1999, Pages 8591-8596

  Lode, Holger N ^a   Xiang, Rong ^a   Duncan, Steven R ^a   Theofilopoulos, Argyrios N ^a   Gillies, Stephen D ^b   Reisfeld, Ralph A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Lexigen Pharmaceuticals Corp   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GANGLIOSIDE ANTIBODY; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RECOMBINANT INTERLEUKIN 12; RECOMBINANT INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW METASTASIS; CANCER GENETICS; CANCER PREVENTION; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE TARGETING; GENE THERAPY; LIVER METASTASIS; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINATION;

ANIMALS; ANTIBODIES, NEOPLASM; ANTINEOPLASTIC AGENTS; CANCER VACCINES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GANGLIOSIDES; GENE THERAPY; IMMUNOTHERAPY; INTERLEUKIN-12; INTERLEUKIN-2; MICE; NEOPLASM TRANSPLANTATION; NEUROBLASTOMA; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; VACCINATION;

ANIMALIA; MURINAE;

EID: 0033587757     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.15.8591     Document Type: Article

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