T cell receptor biases and clonal proliferations among lung transplant recipients with obliterative bronchiolitis

Journal of Clinical Investigation

Volumn 97, Issue 11, 1996, Pages 2642-2650

  Duncan, Steven R ^a   Valentine, Vincent ^b   Roglic, Mihovil ^a   Elias, Darlene J ^a   Pekny, Katherine W ^a   Theodore, James ^b   Kono, Dwight H ^a   Theofilopoulos, Argyrios N ^a,c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^c IMM3 ^*  (United States)

Author keywords

allograft rejection, chronic; organ transplantation; T cell antigen receptors,

Indexed keywords

ALLOANTIGEN; AZATHIOPRINE; CYCLOSPORIN A; GLUCOCORTICOID; T LYMPHOCYTE RECEPTOR;

ADULT; ARTICLE; BRONCHIOLITIS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE SEQUENCE; GRAFT REJECTION; HUMAN; HUMAN CELL; IMMUNOTHERAPY; LUNG BIOPSY; LUNG LAVAGE; LUNG TRANSPLANTATION; MONOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPIROMETRY; T LYMPHOCYTE;

EID: 0029938464     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118714     Document Type: Article

References (39)

1. Duncan, S.R., I.L. Paradis, S. Similo, S.A. Yousem, P. Williams, W. Grugrich, J.P. Dauber, and B.P. Griffith. 1992. Sequelae of cytomegalovirus pulmonary infections in lung allograft recipients. Am. Rev. Resp. Dis. 146:1419-1425.
2. Theodore, J., V.A. Starnes, and N.J. Lewiston. 1990. Obliterative bronchiolitis. Clin. Chest. Med. 11:309-322.
3. Azuma, H., and N.L. Tilney. 1994. Chronic graft rejection. Curr. Opin. Immunol. 6:770-776.
4. Panzara, M.A., J.R. Oksenberg, and L. Steinman. 1992. The polymerase chain reaction for detection of T-cell antigen receptor expression. Curr. Opin. Immunol. 4:205-210.
5. Theofilopoulos, A.N., R. Baccala, R. Gonzalez-Quintial, D.H. Kono, R.S. Balderas, R. MacPhee, S.R. Duncan, and M. Roglic. 1995. T-cell repertoires in health and disease. Ann. NY Acad. Sci. 756:53-65.
6. Theofilopoulos, A.N., R.S. Balderas, R. Baccala, and D.H. Kono. 1992. T-cell receptor genes in autoimmunity. Ann. NY Acad. Sci. 681:53-65.
7. Krensky, A.M., A. Weiss, G. Crabtree, M.M. Davis, and P. Parham. 1990. T-lymphocyte-antigen interactions in transplant rejection. N. Engl. J. Med. 322: 510-517.
8. Colvin, R.B. 1990. Cellular and molecular mechanisms of allograft rejection. Annu. Rev. Med. 41:361-375.
9. Adorini, L., J.C. Guery, G. Rodriguez-Tarduchy, and S. Trembleau. 1993. Selective immunosuppression. Immunol. Today. 14:285-289.
10. Gaur, A., and C.G. Fathman. 1994. Immunotherapeutic strategies directed at the trimolecular complex. Adv. Immunol. 56:219-265.
11. Yousem, S.A., G.J. Berry, E.M. Brunt, D. Chamberlain, R.H. Hruban, R.K. Sibley, S. Stewart, and H.D. Tazelaar. 1990. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: lung rejection study group. J. Heart Transplant. 9:593-601.
12. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid quanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
13. Plaza, A., D.H. Kono, and A.N. Theofilopoulos. 1991. New human Vβ genes and polymorphic variants. J. Immunol. 147:4360-4365.
14. Kono, D.H., R. Baccala, R.S. Balderas, S.J. Kovac, P.W. Heald, R.I. Edelson, and A.N. Theofilopoulos. 1992. Application of a multiprobe RNase protection assay and junction sequences to define Vβ gene diversity in Sezary Syndrome. Am. J. Pathol. 140:823-830.
15. Warrens, A.N., G. Lombardi, and R.I. Lechler. 1994. MHC and alloreactivity. Transplant. Immunol. 2:103-107.
16. Matzinger, P., and M.H. Bevan. 1977. Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens. Cell Immunol. 29:1-5.
17. Miceli, M.C., and O.J. Finn. 1989. T cell receptor β-chain selection in human allograft rejection. J. Immunol. 142:81-86.
18. Frisman, D.M., A.A. Hurwitz, W.T. Bennett, G.W. Dec, L.A. Boyle, J.T. Fallon, R.B. Colvin, and J.T. Kurnick. 1990. Clonal analysis of graft-infiltrating lymphocytes from renal and cardiac biopsies. Hum. Immunol. 28:208-215.
19. Hand, S.L., B.L. Hall, and O.J. Finn. 1990. T-cell receptor gene usage and expression in renal allograft-derived T-cell lines. Hum. Immunol. 28:82-95.
20. Shirwan, H., D. Chi, L. Makowa, and D.V. Cramer. 1993. Lymphocytes infiltrating rat cardiac allografts express a limited repertoire of T cell receptor β genes. J. Immunol. 151:5228-5238.
21. Goss, J.A., R. Pyo, M.W. Glye, J.M. Connolly, and T.H. Hansen. 1993. Major histocompatibility complex-specific prolongation of murine skin and cardiac allograft survival after in vivo depletion of Vβ+ T cells. J. Exp. Med. 177: 35-44.
22. Krensky, A.M., and C. Clayberger. 1994. The induction of tolerance to alloantigens using HLA-base synthetic peptides. Curr. Opin. Immunol. 6:791-796.
23. Shoskes, D.A., and K.J. Wood. 1994. Indirect presentation of MHC antigens in transplantation. Immunol. Today. 15:32-38.
24. Bradley, J.A., A.M. Mowat, and E.M. Bolton. 1992. Processed MHC class I alloantigens as lhe stimulus for CD4+ T-cell dependent antibody-mediated graft rejection. Immunol. Today. 13:434-438.
25. Benchelou, G., P.A. Takizawa, C.A. Olson, M. McMillin, and E.E. Sercarz. 1992. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J. Exp. Med. 175: 305-308.
26. Lee, R.S., M.J. Grusby, L.H. Glimcher, H.J. Winn, and H. Auchincloss. 1994. Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo. J. Exp. Med. 179:865-872.
27. Fangman, J.R., R. Dalchau, and J.W. Fabre. 1992. Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides. J. Exp. Med. 175:1521-1529.
28. Dalchau, R., J.R. Fangman, and J.W. Fabre. 1992. Allorecognition of isolated, denatured chains of class I and class II major histocompatibility complex molecules: evidence for an important role for indirect allorecognition in transplantation. Eur. J. Immunol. 22:669-677.
29. Liu, Z., Y.K. Sun, Y.P. Xi, A. Faffei, E.F. Reed, P. Harris, and N. Suciu-Foca. 1993. Contribution of direct and indirect recognition pathways to T cell alloreactivity. J. Exp. Med. 177:1643-1650.
30. Liu, Z., Y.K. Sun, Y.P. Xi, B. Hong, P. Harris, E.F. Reed, and N. Suciu-Foca. 1993. Limited usage of T cell receptor Vβ genes by allopeptide-specific T cells. J. Immunol. 150:3180-3186.
31. Hedrick, S.M., I. Engel, D.L. McElligott, P.J. Fink, M.L. Hsu, D. Hansburg, and L.A. Matis. 1988. Selection of amino acid sequences in the beta chain of the T cell antigen receptor. Science (Wash. DC). 239:1541-1544.
32. McHeyzer-Williams, M.G., and M.M. Davis. 1995. Antigen-specific development of primary and memory T-cells. Science (Wash. DC). 268:106-111.
33. Heber-Katz, E., and H. Acha-Orbea. 1989. The V-region disease hypothesis: evidence from autoimmune encephalomyelitis. Immunol. Today. 10: 164-169.
34. Duncan, S.R. 1993. Pulmonary complications of transplantation. In Current Pulmonology, Vol. 14. D.F. Tierney, editor. Mosby: Year Book Inc., St. Louis. 199-241.
35. Burke, C.M., J. Theodore, K.D. Dawkins, S.A. Yousem, N. Blank, M.E. Billingham, A. Van Kessel, S.A. Jamieson, P.E. Oyer, J.C. Baldwin, et al. 1984. Post-transplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation. Chest. 86:824-829.
36. Argaet, V.P., C.W. Schmidt, S.R. Burrows, S.L. Silins, M.G. Kurilla, D.L. Doolan, A. Suhrbier, D.J. Moss, E. Kieff, T.B. Sculley, and I.S. Misko. 1994. Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. J. Exp. Med. 180:2335-2340.
37. Morely, J.K., F.M. Batliwalla, R. Hingorani, and P.K. Gregersen. 1995. Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset. J. Immunol. 154:6182-6190.
38. Gonzalez-Quintial, R., R. Baccala, R.M. Pope, and A.N. Theofilopoulos. 1996. Identification of clonally-expanded T cells in rheumatoid arthritis using a sequence enrichment nuclease assay. J. Clin. Invest. 97:1335-1343.
39. Duncan, S.R., K.W. Pekny, M. Roglic, D.J. Elias, and A.N. Theofilopoulos. 1995. T cell Vβ repertoire biases and clonal proliferation in malignant pleural effusions. Am. J. Respir. Crit. Care Med. 151:A212. (Abstr.)