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Volumn 2, Issue 12, 1996, Pages 1951-1959

Activation of human effector cells by a tumor reactive recombinant anti-ganglioside GD2 interleukin-2 fusion protein (ch14.18-IL2)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC ANTIBODY; GANGLIOSIDE GD2 ANTIBODY; HYBRID PROTEIN; RECOMBINANT FUSION PROTEIN; RECOMBINANT INTERLEUKIN 2; UNCLASSIFIED DRUG;

EID: 0030470861     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (73)

References (29)
  • 2
    • 0025342187 scopus 로고
    • Natural killer cells activated by Interleukin-2 treatment in vivo respond to Interleukin-2 primarily through the p75 receptor and maintain the p55 (TAC) negative phenotype
    • Weil-Hillman, G., Voss, S. D., Finch, P., Schell, K., Hank, J. A., Sosman, J. A., Sugamura, K., and Sondel, P. M. Natural killer cells activated by Interleukin-2 treatment in vivo respond to Interleukin-2 primarily through the p75 receptor and maintain the p55 (TAC) negative phenotype. Cancer Res., 50: 2683-2691, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 2683-2691
    • Weil-Hillman, G.1    Voss, S.D.2    Finch, P.3    Schell, K.4    Hank, J.A.5    Sosman, J.A.6    Sugamura, K.7    Sondel, P.M.8
  • 3
    • 0023804208 scopus 로고
    • Repetitive weekly cycles of interleukin-2. II. Clinical and immunologic effects of dose, schedule, and indomethacin
    • Sosman, J. A., Kohler, P C., Hank, J. A., Moore, K. H., Bechhofer, R., Storer, B., and Sondel, P M. Repetitive weekly cycles of interleukin-2. II. Clinical and immunologic effects of dose, schedule, and indomethacin. J. Natl. Cancer Inst., 80: 1451-1460, 1988.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 1451-1460
    • Sosman, J.A.1    Kohler, P.C.2    Hank, J.A.3    Moore, K.H.4    Bechhofer, R.5    Storer, B.6    Sondel, P.M.7
  • 5
    • 0023485232 scopus 로고
    • In vivo and in vitro activation of natural killer cells in advanced cancer patients undergoing recombinant interleukin-2 and LAK cell therapy
    • Phillips, J. H., Gernlo, B. T., Myers, W. W., Rayner, A. A., and Lanier, L. L. In vivo and in vitro activation of natural killer cells in advanced cancer patients undergoing recombinant interleukin-2 and LAK cell therapy. J. Clin. Oncol., 5: 1933-1941, 1987.
    • (1987) J. Clin. Oncol. , vol.5 , pp. 1933-1941
    • Phillips, J.H.1    Gernlo, B.T.2    Myers, W.W.3    Rayner, A.A.4    Lanier, L.L.5
  • 6
    • 0023868619 scopus 로고
    • In vivo effects of recombinant IL-2. I. Isolation of circulating leul9+ lymphokine-activated killer effector cells from cancer patients receiving recombinant IL-2
    • McMannis, J. D., Fisher, R. I., Creekmore, S. P., Braun, D. P., Harris, J. E., and Ellis, T. M. In vivo effects of recombinant IL-2. I. Isolation of circulating leul9+ lymphokine-activated killer effector cells from cancer patients receiving recombinant IL-2 J. Immunol., 140: 1335-1340, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 1335-1340
    • McMannis, J.D.1    Fisher, R.I.2    Creekmore, S.P.3    Braun, D.P.4    Harris, J.E.5    Ellis, T.M.6
  • 8
    • 0027052069 scopus 로고
    • Phase I trial of murine monoclonal antibody L6 in combination with subcutaneous interleukin-2 in patients with advanced carcinoma of the breast, colorectum, and lung
    • Ziegler, L. D., Palazzolo, P., Cunningham, J., Janus, M., Itoh, K., Hayakawa, K., Hellstrom, J., Hellstrom, K. E., Nicaise, C., and Dennin, R. Phase I trial of murine monoclonal antibody L6 in combination with subcutaneous interleukin-2 in patients with advanced carcinoma of the breast, colorectum, and lung J. Clin. Oncol., 10: 1470-1478, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1470-1478
    • Ziegler, L.D.1    Palazzolo, P.2    Cunningham, J.3    Janus, M.4    Itoh, K.5    Hayakawa, K.6    Hellstrom, J.7    Hellstrom, K.E.8    Nicaise, C.9    Dennin, R.10
  • 9
    • 0024308235 scopus 로고
    • Lymphokine-activated killer activity induced by in vivo interleukin 2 therapy: Predominant role for lymphocytes with increased expression of CD2 and Leu19 antigens but negative expression of CD16 antigens
    • Weil-Hillman, G., Fisch, P., Prieves, A. F. Sosman, J. A., Hank, J. A., and Sondel, P. M. Lymphokine-activated killer activity induced by in vivo interleukin 2 therapy: predominant role for lymphocytes with increased expression of CD2 and Leu19 antigens but negative expression of CD16 antigens. Cancer Res., 49: 3680-3688, 1989
    • (1989) Cancer Res. , vol.49 , pp. 3680-3688
    • Weil-Hillman, G.1    Fisch, P.2    Prieves, A.F.3    Sosman, J.A.4    Hank, J.A.5    Sondel, P.M.6
  • 10
    • 0026572996 scopus 로고
    • Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells
    • Gillies, S D , Reilly, E. B., Lo, K M., and Reisfeld, R. A. Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells. Proc. Natl. Acad. Sci USA, 89: 1428-1432, 1992.
    • (1992) Proc. Natl. Acad. Sci USA , vol.89 , pp. 1428-1432
    • Gillies, S.D.1    Reilly, E.B.2    Lo, K.M.3    Reisfeld, R.A.4
  • 11
    • 0028060152 scopus 로고
    • A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice
    • Sabzevari, H., Gillies, S. D., Mueller, B. M., Pancook, I. D., and Reisfeld, R. A. A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice. Proc. Natl. Acad. Sci. USA, 91: 9626-9630, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9626-9630
    • Sabzevari, H.1    Gillies, S.D.2    Mueller, B.M.3    Pancook, I.D.4    Reisfeld, R.A.5
  • 12
    • 0029866441 scopus 로고    scopus 로고
    • Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins
    • Becker, J. C., Pancook, J. D., Gillies, S. D., Mendelsohn, J., Reisfeld, R. A. Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins. Proc. Natl Acad. Sci. USA, 93: 2702-2707, 1996.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 2702-2707
    • Becker, J.C.1    Pancook, J.D.2    Gillies, S.D.3    Mendelsohn, J.4    Reisfeld, R.A.5
  • 13
    • 0029890827 scopus 로고    scopus 로고
    • T cell mediated eradication of murine metastatic melanoma Induced by targeted Interleukin 2 therapy
    • Becker, J. C., Pancook, J. D., Gillies, S. D., Furukawa, K., and Reisfeld, R. A. T cell mediated eradication of murine metastatic melanoma Induced by targeted Interleukin 2 therapy. J. Exp. Med., 183: 2361-2366, 1996.
    • (1996) J. Exp. Med. , vol.183 , pp. 2361-2366
    • Becker, J.C.1    Pancook, J.D.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 14
    • 0023821499 scopus 로고
    • The international standard for human interleukin-2. Calibration by international collaborative study
    • Gearing, A. J. H., and Thorpe. R The international standard for human interleukin-2. Calibration by international collaborative study. J. Immunol. Methods, 114: 3-9, 1988.
    • (1988) J. Immunol. Methods , vol.114 , pp. 3-9
    • Gearing, A.J.H.1    Thorpe, R.2
  • 15
    • 0025021639 scopus 로고
    • Enhancement of antibody-dependent cytotoxicity with chimeric anti-GD2 antibody
    • Mueller, B. M., Romberdahl, C. A., Gillies, S. D., and Reisfeld, R. A. Enhancement of antibody-dependent cytotoxicity with chimeric anti-GD2 antibody. J. Immunol., 144: 1282-1286, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 1282-1286
    • Mueller, B.M.1    Romberdahl, C.A.2    Gillies, S.D.3    Reisfeld, R.A.4
  • 16
    • 0025891798 scopus 로고
    • Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody
    • Gillies, S. D., Young, D., Lo, K-M., Foley, S. F., and Reisfeld, R. A. Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody. Hybridoma, 10: 347-356, 1991.
    • (1991) Hybridoma , vol.10 , pp. 347-356
    • Gillies, S.D.1    Young, D.2    Lo, K.-M.3    Foley, S.F.4    Reisfeld, R.A.5
  • 17
    • 0023890374 scopus 로고
    • Clinical and immunological effects of recombinant Interleukin-2 given by repetitive weekly cycles to patients with cancer
    • Sondel, P. M., Kohler, P. C., Hank, J. A., Moore, K. H., Rosenthal, N., Sosman, J., Bechhofer, R , and Storer, B. Clinical and immunological effects of recombinant Interleukin-2 given by repetitive weekly cycles to patients with cancer. Cancer Res., 48: 2561-2567, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 2561-2567
    • Sondel, P.M.1    Kohler, P.C.2    Hank, J.A.3    Moore, K.H.4    Rosenthal, N.5    Sosman, J.6    Bechhofer, R.7    Storer, B.8
  • 19
    • 3042932317 scopus 로고
    • Characterization of the interleukin 2 receptor B chain using 3 distinct monoclonal antibodies
    • Tsudo, M., Kitamura, F., and Miyasaka, M. Characterization of the interleukin 2 receptor B chain using 3 distinct monoclonal antibodies. Proc. Natl. Acad. Sci. USA. 86: 1982-1986, 1989.
    • (1989) Proc. Natl. Acad. Sci. USA. , vol.86 , pp. 1982-1986
    • Tsudo, M.1    Kitamura, F.2    Miyasaka, M.3
  • 20
    • 0027177881 scopus 로고
    • Humanized Mik β 1: A humanized antibody to the IL-2 receptor beta-chain that acts synersistically with humanized anti-TAC
    • Hakimi, J., Ha, V. C., Lin, P., Campbell, E., Gately, M. K., Tsudo, M., Payne, P. W., Waldman, T. A., Grant, A, J., and Tsien, W. H. Humanized Mik β 1: a humanized antibody to the IL-2 receptor beta-chain that acts synersistically with humanized anti-TAC. J. Immunol., 151: 1075-1085, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 1075-1085
    • Hakimi, J.1    Ha, V.C.2    Lin, P.3    Campbell, E.4    Gately, M.K.5    Tsudo, M.6    Payne, P.W.7    Waldman, T.A.8    Grant, A.J.9    Tsien, W.H.10
  • 21
    • 0026734981 scopus 로고
    • Characterization of the Interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: Association of the p64 IL-2R γ chain with the IL-2R γ chain with the Il-2R β chain in functional intermediate-affinity IL-2R
    • Voss, S. D., Sondel, P. M., and Robb, R. J. Characterization of the Interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R γ chain with the IL-2R γ chain with the Il-2R β chain in functional intermediate-affinity IL-2R. J. Exp. Med., 176: 531-541, 1992.
    • (1992) J. Exp. Med. , vol.176 , pp. 531-541
    • Voss, S.D.1    Sondel, P.M.2    Robb, R.J.3
  • 22
    • 0025877853 scopus 로고
    • Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab′) with specificity for carcinomas and human IL-2
    • Fell, H. P., Gayle, M. A., Grosmaire, L., and Ledbetter, J. A. Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab′) with specificity for carcinomas and human IL-2. J. Immunol., 146: 2446-2452, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 2446-2452
    • Fell, H.P.1    Gayle, M.A.2    Grosmaire, L.3    Ledbetter, J.A.4
  • 23
    • 0025093462 scopus 로고
    • Depressed in vitro T cell responses concomitant with augmented Interleukin-2 responses by lymphocytes from cancer patients following in vivo treatment with interleukin-2
    • Hank, J. A., Sosman, J. A., Kohler, P. C., Bechhofer, R., Storer, B., and Sondel, P. M. Depressed in vitro T cell responses concomitant with augmented Interleukin-2 responses by lymphocytes from cancer patients following in vivo treatment with interleukin-2. J. Biol. Response Modif., 9: 5-14, 1990.
    • (1990) J. Biol. Response Modif. , vol.9 , pp. 5-14
    • Hank, J.A.1    Sosman, J.A.2    Kohler, P.C.3    Bechhofer, R.4    Storer, B.5    Sondel, P.M.6
  • 24
    • 0025091247 scopus 로고
    • Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant Interleukin-2
    • Hank, J. A. Robinson, R. R., Surfus, J., Mueller, B. M., Reisfeld, R. A., Cheung, N-K., and Sondel, P. M. Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant Interleukin-2. Cancer Res., 50: 5234-5239, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 5234-5239
    • Hank, J.A.1    Robinson, R.R.2    Surfus, J.3    Mueller, B.M.4    Reisfeld, R.A.5    Cheung, N.-K.6    Sondel, P.M.7
  • 25
    • 0023549559 scopus 로고
    • Interleukin-2 enhancement of monoclonal antibody mediated cellular cytotoxicity against human melanoma
    • Munn, D. H., and Cheung, N. K. V. Interleukin-2 enhancement of monoclonal antibody mediated cellular cytotoxicity against human melanoma. Cancer Res., 47: 6600-6605, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 6600-6605
    • Munn, D.H.1    Cheung, N.K.V.2
  • 27
    • 0027598183 scopus 로고
    • Biological activity and in vivo clearance of antitumor antibody/cytokine fusion proteins
    • Gillies, S. D, Young, D., Lo, K-M., and Roberts, S. Biological activity and in vivo clearance of antitumor antibody/cytokine fusion proteins. Bioconjugate Chem., 4: 230-235, 1993.
    • (1993) Bioconjugate Chem. , vol.4 , pp. 230-235
    • Gillies, S.D.1    Young, D.2    Lo, K.-M.3    Roberts, S.4


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