Lack of responsiveness to TGF-β1 in a thyroid carcinoma cell line with functional type I and type II TGF-β receptors and Smad proteins, suggests a novel mechanism for TGF-β insensitivity in carcinoma cells

Molecular and Cellular Endocrinology

Volumn 153, Issue 1-2, 1999, Pages 79-90

  Heldin, Nils Erik ^a   Bergström, Daniel ^a   Hermansson, Annika ^a   Bergenstråhle, Annika ^a   Nakao, Atsuhito ^b   Westermark, Bengt ^a   Ten Dijke, Peter ^b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Anaplastic; SMADs; TGF receptors; TGF signalling; Thyroid carcinoma

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANAPLASTIC CARCINOMA; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER RESISTANCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RECEPTOR BINDING; SIGNAL TRANSDUCTION; THYROID CARCINOMA;

ACTIVIN RECEPTORS, TYPE I; CARCINOMA; CELL DIVISION; DNA-BINDING PROTEINS; GENE EXPRESSION; GENES, MYC; HUMANS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD6 PROTEIN; SMAD7 PROTEIN; THYROID NEOPLASMS; TRANS-ACTIVATORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0033587629     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00086-6     Document Type: Article

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