ITM2A is induced during thymocyte selection and T cell activation and causes downregulation of CD8 when overexpressed in CD4+CD8+ double positive thymocytes

Journal of Experimental Medicine

Volumn 190, Issue 2, 1999, Pages 217-228

  Kirchner, Jacqueline ^a   Bevan, Michael J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

ITM2A; Positive selection; T cell activation; T cell development; Thymocyte

Indexed keywords

CD8 ANTIGEN;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CELL MATURATION; CELL SELECTION; CELL SURFACE; CELLULAR DISTRIBUTION; CYTOPLASM VESICLE; GENE LOCATION; GENE OVEREXPRESSION; GOLGI COMPLEX; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; THYMOCYTE; THYMUS;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; CELL DIFFERENTIATION; DNA PRIMERS; DNA-BINDING PROTEINS; DOWN-REGULATION; FEMALE; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; T-LYMPHOCYTE SUBSETS;

EID: 0033584235     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.2.217     Document Type: Article

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