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19
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0013577618
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note
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Other examples of tethered RCM reactions using substrates i-iv have been described. (Formula presented)
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24
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85022455957
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e) Forbes, M. D. E.; Patton, J. T.; Myers, T. L.; Maynard, H. D.; Smith, D. W.; Schulz, G. R.; Wagener, K. B. J. Am. Chem. Soc. 1992, 114, 10978-10980.
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Wagener, K.B.7
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26
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0013628341
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note
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2 or pyridine in toluene (DMAP was used to catalyze the formation of the hindered ketal 4g) The yields of silaketal formation were: 4a (84%), 4b (82%), 4c (60%), 4d (55%), 4e (73%), 4f (60%), 4g (75%), 10a (60%), and 10b (60%).
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27
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0000420768
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Gillard, J. W.; Fortin, R.; Morton, H. E.; Yoakim, C.; Quesnelle, C. A.; Daignault, S.; Guindon, Y. J. Org. Chem. 1988, 53, 2602-2608.
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37049074175
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31
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0013605008
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note
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We have observed other instances in which slow addition of initiator carbene was advantageous and will report on these observations elsewhere.
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32
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0000681082
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t-Butylethylene also shows a negligible rate of reaction with 2: Ulman, M.; Grubbs, R. H. Organometallics 1998, 17, 2484-2489.
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Ulman, M.1
Grubbs, R.H.2
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33
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0013601164
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note
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2.
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34
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0013613702
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note
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1H NMR resonances for the minor isomer in each case indicated that it was a symmetrical structure, thereby ruling out the possibility of regioisomeric alkenes.
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36
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0030786787
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These previous examples of formation of cyclic alkenes having one fewer carbon than expected were proposed to have been preceded by alkene isomerizalion. Our experimental evidence now directly supports that suggestion. Also, the earlier examples were obtained using a Schrock molybdenum carbene; the observations described here are to our knowledge the first example where a ruthenium carbene has induced this event.
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b) Joe, D.; Overman, L. E. Tetrahedron Lett. 1997, 38, 8635-8638. These previous examples of formation of cyclic alkenes having one fewer carbon than expected were proposed to have been preceded by alkene isomerizalion. Our experimental evidence now directly supports that suggestion. Also, the earlier examples were obtained using a Schrock molybdenum carbene; the observations described here are to our knowledge the first example where a ruthenium carbene has induced this event.
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Tetrahedron Lett.
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Joe, D.1
Overman, L.E.2
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