An unexpected product arising from metal alkylidene mediated ring-closing diene metathesis

Tetrahedron Letters

Volumn 38, Issue 50, 1997, Pages 8635-8638

  Joe, Daisy ^a   Overman, Larry E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENE;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; ISOMERISM; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS;

EID: 0030786787     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)10373-2     Document Type: Article

References (31)

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15. 2, M).
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19. Extensive investigation of reaction conditions was precluded by the limited amounts of 3 that were available. Qualitatively similar results were seen in metathesis reactions of 3 employing 20 mol% of 8.
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26. 6 at 70 °C. b Only definite connectivities are reported; numbers refer to hydrogens. c Assignments for H-4 and H-10 may be interchanged. d The homonuclear correlation is due to allylic coupling.
27. 1HNMR. At short reaction times, the ratio of 9:10 was -1:1.
28. 23
29. 24
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31. Such processes are precedented with tantalum and niobium alkylidene complexes, see, for example: Schrock, R. R. In Inorganic Chemistry: Toward the 21st Century; Chisholm, M. H., Ed.; ACS Symposium Series 211; American Chemical Society: Washington, DC, 1983; Chapter 25.